Results 71 to 80 of about 1,407,805 (180)

Bacteriophage and Fusidic Acid Have Synergistic Effect Against Meticillin‐Resistant Staphylococcus pseudintermedius in Ex Vivo Canine Dermis Model

open access: yesVeterinary Dermatology, Volume 37, Issue 2, Page 200-210, April 2026.
Background: Antimicrobial stewardship has become vital given the progressive emergence of multidrug‐resistant bacteria, and novel approaches to the treatment of bacterial infections are needed. Recently, reported synergistic effects of antibacterial drugs and bacteriophage therapy have revealed promising applications for the management of meticillin ...
Sarah Ehling   +9 more
wiley   +1 more source

从单方成药到“分子中药学”和“组合中药学”

open access: yes, 2002
对中药现代化的问题进行评述 ,从中药研究的现代基础理论到方法学所提出的一系列创新的观点和方法进行了系统的阐述。主张从 3个方向对中药进行现代化研究 ,三方面同时进行 ,不要只顾一方面而忽视其他 ,不要互相排斥 ,生药、单方颗粒和组合中药 3种产品同时进入市场。一方面直接使用生药 ,完全保留传统中药的处方、煎药和服用的治疗方法 ,仅仅加强生药的质量研究和管理 ,定点栽培中药 ,制定中药饮片的质量标准 ;另一方面保留中药的全成分 ,用现代制药技术将中药制备为单方颗粒 ,并以此进行复方的配制 ,做到质量可控
吴凤锷
core  

Analysis of key therapeutic elements in acupuncture therapy and placebo acupuncture controls

open access: yesWorld Journal of Acupuncture - Moxibustion
Identifying key acupuncture elements is essential for optimizing sham acupuncture controls. Based on the characteristics and current state of acupuncture therapy, this paper categorizes key acupuncture elements into types and contents.
Jian-fei NIU   +5 more
doaj   +1 more source

Efficacy of Der f 2/Zen 1‐LAMP1 Plasmid‐Based Vaccine Immunotherapy in Dogs With Atopic Dermatitis: A Proof‐of‐Concept Study

open access: yesVeterinary Dermatology, Volume 37, Issue 2, Page 306-318, April 2026.
Background: DNA‐based vaccination rapidly induces strong cellular and humoral immune responses, which may be enhanced by inclusion of lysosomal‐associated membrane protein‐1 (LAMP). Objectives: This proof‐of‐concept study evaluated the efficacy and safety of a Der f 2/Zen 1‐LAMP‐based DNA vaccine immunotherapy in client‐owned dogs with nonseasonal AD ...
Petra Bizikova   +6 more
wiley   +1 more source

通过共有化合物建立中药药效和现代药理间的联系

open access: yes, 2005
共有化合物是一类同时存在于多种具有相同药效的中药中的化合物。本研究寻找并分析了“泻下”、“止痛”和“清热”3类共有化合物 ,发现其现代药理活性与所属中药药效类别有很强的联系 ...
刘海波, 陆爱军, 刘冰, 周家驹
core  

Study on the formula of Traditional Chinese Medicine diet for perianal abscess based on ancient books (基于古籍挖掘的肛周脓肿中医药膳组方研究)

open access: yes中西医结合护理
Objective To analyze the prescription rules of traditional Chinese medicinal diet for perianal abscess by data mining technology, so as to provide theoretical guidance for the individualized dietary care and the development of medicinal diet for ...
HAN Peiqi (韩珮琦)   +4 more
doaj   +1 more source

Global Research Trends in Dietary Polyphenols for Preventing Non‐Communicable Chronic Diseases: A Bibliometric Study

open access: yesFood Science &Nutrition, Volume 14, Issue 3, March 2026.
This graphical abstract summarizes a bibliometric study on dietary polyphenols for preventing non‐communicable chronic diseases. It shows publication growth from 1998 to 2024, highlights core themes (oxidative stress, inflammation) and hotspots (metabolic syndrome, gut microbiota), and outlines future priorities like long‐term human studies.
Xinjiang Huang   +4 more
wiley   +1 more source

浅谈中成药的合理运用

open access: yes, 1995
中成药在临床多应用于常见病和多发病,具有疗效好、服用方便、便于携带、便于保存的优点。但要充分发挥药效,又不产生毒副作用,应遵循,①根据疾病性质选择不同剂型;②根据不同剂型的特性选择药物;③便于患者服用;④中成药与西药应合理配用 ...
陈谦信, 韩秀珍
core  

泻下药和解表药的现代药理解释

open access: yes, 2007
目的在中药现代化的进程中,对中医药体系中的传统药效的现代药理学解释是一项有深远意义的工作。本实验设计了3种方法,在总体上对中药的传统药效与中药的现代药理活性进行对比分析,从中发现规律,对被研究的中药药效给出言之有据的解释。方法收集大量中药传统药效、中药现代药理活性和中药所含活性化合物现代药理活性数据,通过统计方法寻找特定中药药效类别(泻下和解表)的现代药理学的特征,从而得到其现代药理学解释。结果使用的3种方法都能够给出与2种药效相关的现代药理活性。汇总3种结果得到,泻下与导泄、兴奋胃肠平滑肌 ...
刘海波, 周家驹, 乔颖欣
core  

髓源性抑制细胞是乳腺癌进展的潜在因素和重要靶点

open access: yes浙江大学学报. 医学版
由于缺乏有效的治疗手段,复发转移仍然是乳腺癌患者死亡的主要原因。在转移发生之前,远处器官内已经形成了适合乳腺癌细胞生长的微环境——转移前生态位(PMN)。髓源性抑制细胞(MDSC)是一类具有免疫抑制作用的异质性未成熟髓系细胞群,可在乳腺癌患者体内大量扩增,参与PMN的形成。MDSC不仅支持乳腺癌细胞免疫逃逸,而且还可通过重塑肺血管内皮细胞外基质、招募癌症干细胞来促进乳腺癌转移的发生。此外,MDSC还能通过削弱免疫疗法的抗肿瘤效率来降低药物的治疗效果。因此 ...
杜 楠楠   +4 more
doaj   +1 more source

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