Results 61 to 70 of about 25,245 (172)

Global Research Trends in Dietary Polyphenols for Preventing Non‐Communicable Chronic Diseases: A Bibliometric Study

open access: yesFood Science &Nutrition, Volume 14, Issue 3, March 2026.
This graphical abstract summarizes a bibliometric study on dietary polyphenols for preventing non‐communicable chronic diseases. It shows publication growth from 1998 to 2024, highlights core themes (oxidative stress, inflammation) and hotspots (metabolic syndrome, gut microbiota), and outlines future priorities like long‐term human studies.
Xinjiang Huang   +4 more
wiley   +1 more source

不同尺寸生物材料应用于实体肿瘤过继细胞免疫疗法研究进展

open access: yes浙江大学学报. 医学版
过继细胞输注(ACT)疗法在血液系统肿瘤的治疗中疗效显著,但在实体瘤的治疗中存在归巢不良、免疫抑制及潜在毒副作用等问题。近年来,不同尺寸的生物材料(如纳米粒、微球/微贴片和水凝胶)在细胞体外工程化、在体递送及肿瘤微环境调控等方面展现出独特优势。纳米粒可用于基因递送、人工抗原呈递系统构建和免疫微环境重塑;微球和微贴片增强了免疫细胞的扩增、靶向激活及局部滞留;水凝胶则通过在体基因工程化、三维培养支持和细胞因子共递送等方式提升ACT疗效。本文综述了ACT中不同尺寸生物材料在提升递送效率 ...
陈 佳新   +3 more
doaj   +1 more source

Traditional Chinese Medicine nursing by regulating Liver for patients with hyperthyroidism (甲状腺功能亢进症的中医从肝护理)

open access: yes中西医结合护理, 2022
Hyperthyroidism, as known as goiter in Traditional Chinese Medicine (TCM), is a common endocrine disease which mainly affecting the thyroid gland. According to TCM theorysyndrome of liver-qi stagnation may be the main factor leading to the occurrence of ...
ZHANG Xixia (章细霞)   +2 more
doaj   +1 more source

The effects of Tao-Hong-Si-Wu on hepatic necroinflammatory activity and fibrosis in murine model of chronic liver disease [PDF]

open access: yes, 2016
背景:桃红四物汤原名加味四物汤,载于《医垒元戎》,录自《玉机微义》,是在四物汤的基础上加桃仁、红花而成,是活血养血之代表方。桃红四物汤在临床上应用广泛,诸多研究表明桃红四物汤对多种慢性肝病有一定的治疗作用。慢性肝损伤伴肝纤维化发展过程中存在明显的病理性血管生成与重构,阻碍了肝纤维化的逆转与恢复。通过桃红四物汤对病理性血管生成作用的研究,发现部分活血化瘀中药具有抑制病理性血管生成的作用,抗病理性血管生成可能是活血化瘀药的现代药理作用之一 ...
史萌萌
core  

Astragalus Polysaccharides Can Effectively Alleviate Cognitive Impairment in Mice With Alzheimer's Disease by Regulating the Gut Microbiota

open access: yesFood Science &Nutrition, Volume 14, Issue 3, March 2026.
This schematic diagram illustrates that Astragalus polysaccharides improve cognitive dysfunction in 3xTg AD mice by regulating the gut‐brain axis. APS ameliorates gut microbiota and enhances intestinal barrier function, thereby reducing systemic and central inflammation, inhibiting microglial overactivation, and alleviating Aβ deposition and Tau ...
Xilian Wang   +13 more
wiley   +1 more source

敲低核蛋白1通过抑制软骨细胞铁死亡延缓骨关节炎病理进展

open access: yes浙江大学学报. 医学版
目的研究核蛋白(Nupr)1调控软骨细胞铁死亡在骨关节炎进展中的作用及机制。方法将小鼠膝关节软骨细胞分为小干扰RNA(siRNA)对照组、靶向Nupr1的siRNA(siNupr1)组、siRNA对照+IL-1β组(siRNA对照干扰24 h后再加入10 ng/mL IL-1β)和siNupr1+IL-1β组(siNupr1干扰24 h后再加入10 ng/mL IL-1β)。采用蛋白质印迹法和定量逆转录聚合酶链反应法分别检测Nupr1蛋白及其信使RNA(mRNA)表达。采用细胞计数试剂盒(CCK ...
廖 太阳   +6 more
doaj   +1 more source

Clinical application of the three-step auricular acupoint therapy for 23 patients with primary tinnitus (耳穴”三序”疗法治疗原发性耳鸣23例)

open access: yes中西医结合护理, 2022
Objective To investigate the effect of a three-step auricular acupoint therapy in the treatment of primary tinnitus. Methods The clinical data of 23 patients with primary tinnitus were retrospectively analyzed.
LIU Qing (刘青)   +7 more
doaj   +1 more source

Preparation and Application of Monoclonal Antibody against Puerarin [PDF]

open access: yes, 2012
葛根为豆科植物野葛或粉葛的干燥根,为常用中药之一,具有解肌退热、生津、透疹、升阳止泻的功效,多用于治疗外感发热、头痛、项强、消渴、麻疹不透、热痢、泄泻、高血压等症状。葛根素(Puerarin,PU)是葛根的主要活性成分,属于黄酮类化合物,药理作用广泛,是一种很有开发前景的药物。 本实验采用杂交瘤技术制备葛根素的单克隆抗体,在此基础上建立葛根素的酶联免疫吸附分析法检测技术,对葛根中药及中成药中葛根素的含量进行检测和评价。 主要的实验结果如下: (1)采用高碘酸钠法合成免疫人工抗原PU ...
吴俊杰
core  

“Not a Single Leaf Is Meant to be Taken With You”: Conservation Motivations and Belief Systems in a Khasi Sacred Landscape of Meghalaya, India “一片叶子都不许带走”:印度梅加拉亚邦卡西族神圣景观中的保护动机与信仰体系

open access: yesIntegrative Conservation, Volume 5, Issue 1, Page 5-9, March 2026.
This study examines the Mawphlang Sacred Forest in Meghalaya as a culturally embedded model of community‐led conservation. Drawing on qualitative fieldwork, it highlights how spiritual reverence, sacred taboos, and ancestral authority shape ecological stewardship, complementing formal governance systems.
Mrinal Saikia
wiley   +1 more source

茯苓酸可促进前脂肪细胞棕色化及脂代谢

open access: yes浙江大学学报. 医学版
目的:探究茯苓酸对前脂肪细胞棕色化及脂代谢的影响。方法:采用棕色鸡尾酒法诱导3T3-L1 MBX细胞向米色脂肪细胞分化,建立棕色化体系。利用CCK-8法检测不同浓度茯苓酸对3T3-L1 MBX细胞存活率的影响;油红O染色观察茯苓酸作用后脂滴形成情况;定量逆转录聚合酶链反应检测棕色化关键基因解偶联蛋白(Ucp)1、过氧化物酶体增殖物激活受体γ辅激活子(Pgc)-1α、含PR结构域16转录因子(Prdm16),脂肪生成相关基因固醇调节元件结合蛋白(Srebp)1c、乙酰辅酶A羧化酶(Acc)、脂肪酸合酶 ...
陈 坤铃   +5 more
doaj   +1 more source

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