Results 51 to 60 of about 1,407,805 (180)

The rapid antidepressant effect of acupuncture on two animal models of depression by increasing the expression of synaptic proteins in the prefrontal cortex

open access: yesWorld Journal of Acupuncture - Moxibustion
Objective: To investigate the effect of acupuncture onset time and synaptic structure in two different models of depression. Methods: A total of 150 healthy male adult SPF C57BL/6J mice were divided into five time-point groups: 1 h, 3 h, 6 h, 12 h and 24
Bai-le NING   +11 more
doaj   +1 more source

Advance in the clinical studies on Traditional Chinese Medicine hot ironing compress therapy (中药热熨敷技术的临床研究进展)

open access: yes中西医结合护理, 2021
Traditional Chinese Medicine (TCM) hot ironing compress therapy is a common external intervention of Traditional Chinese Medicine nursing techniques.
DENG Jianhua (邓建华)   +5 more
doaj   +1 more source

Harnessing Trace Elements: Novel Radiosensitization Strategies for Enhanced Cancer Radiotherapy

open access: yesRare Metals, Volume 45, Issue 6, June 2026.
ABSTRACT Radiotherapy (RT) is one of the core methods of comprehensive cancer treatment. Globally, more than 40% of cancer patients rely on radiotherapy to achieve tumor control, cure or palliative relief. However, radiation resistance, immunosuppression and normal tissue injury limit its clinical application.
Yuhuan Zhang   +6 more
wiley   +1 more source

不同尺寸生物材料应用于实体肿瘤过继细胞免疫疗法研究进展

open access: yes浙江大学学报. 医学版
过继细胞输注(ACT)疗法在血液系统肿瘤的治疗中疗效显著,但在实体瘤的治疗中存在归巢不良、免疫抑制及潜在毒副作用等问题。近年来,不同尺寸的生物材料(如纳米粒、微球/微贴片和水凝胶)在细胞体外工程化、在体递送及肿瘤微环境调控等方面展现出独特优势。纳米粒可用于基因递送、人工抗原呈递系统构建和免疫微环境重塑;微球和微贴片增强了免疫细胞的扩增、靶向激活及局部滞留;水凝胶则通过在体基因工程化、三维培养支持和细胞因子共递送等方式提升ACT疗效。本文综述了ACT中不同尺寸生物材料在提升递送效率 ...
陈 佳新   +3 more
doaj   +1 more source

Evaluating Ballot Initiative Results for Adult‐Use Marijuana in Ohio: Understanding County‐Level Support

open access: yesPolitics &Policy, Volume 54, Issue 3, June 2026.
ABSTRACT In the 2023 November election, Ohioans voted in favor of Issue 2—the Marijuana Legalization Initiative. The successful passing of this initiative at the ballot box made Ohio the 24th state and largest Republican voting state to adopt a recreational adult‐use marijuana policy. Issue 2 was voted in favor of by a margin of 57% to 43%.
Gideon Cunningham   +2 more
wiley   +1 more source

敲低核蛋白1通过抑制软骨细胞铁死亡延缓骨关节炎病理进展

open access: yes浙江大学学报. 医学版
目的研究核蛋白(Nupr)1调控软骨细胞铁死亡在骨关节炎进展中的作用及机制。方法将小鼠膝关节软骨细胞分为小干扰RNA(siRNA)对照组、靶向Nupr1的siRNA(siNupr1)组、siRNA对照+IL-1β组(siRNA对照干扰24 h后再加入10 ng/mL IL-1β)和siNupr1+IL-1β组(siNupr1干扰24 h后再加入10 ng/mL IL-1β)。采用蛋白质印迹法和定量逆转录聚合酶链反应法分别检测Nupr1蛋白及其信使RNA(mRNA)表达。采用细胞计数试剂盒(CCK ...
廖 太阳   +6 more
doaj   +1 more source

Clinical application of the three-step auricular acupoint therapy for 23 patients with primary tinnitus (耳穴”三序”疗法治疗原发性耳鸣23例)

open access: yes中西医结合护理, 2022
Objective To investigate the effect of a three-step auricular acupoint therapy in the treatment of primary tinnitus. Methods The clinical data of 23 patients with primary tinnitus were retrospectively analyzed.
LIU Qing (刘青)   +7 more
doaj   +1 more source

A Population‐Based Nomogram for Predicting Overall Survival in Pulmonary Sarcomatoid Carcinoma With Real‐World External Validation

open access: yesCancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background Pulmonary sarcomatoid carcinoma (PSC) is a rare and highly aggressive tumor. This study aimed to investigate the prognostic factors of PSC and develop a new risk classifier to predict patients' overall survival (OS). Methods This retrospective study consisted of 675 PSC patients registered in the Surveillance, Epidemiology, and End ...
Shuwen Cui   +13 more
wiley   +1 more source

茯苓酸可促进前脂肪细胞棕色化及脂代谢

open access: yes浙江大学学报. 医学版
目的:探究茯苓酸对前脂肪细胞棕色化及脂代谢的影响。方法:采用棕色鸡尾酒法诱导3T3-L1 MBX细胞向米色脂肪细胞分化,建立棕色化体系。利用CCK-8法检测不同浓度茯苓酸对3T3-L1 MBX细胞存活率的影响;油红O染色观察茯苓酸作用后脂滴形成情况;定量逆转录聚合酶链反应检测棕色化关键基因解偶联蛋白(Ucp)1、过氧化物酶体增殖物激活受体γ辅激活子(Pgc)-1α、含PR结构域16转录因子(Prdm16),脂肪生成相关基因固醇调节元件结合蛋白(Srebp)1c、乙酰辅酶A羧化酶(Acc)、脂肪酸合酶 ...
陈 坤铃   +5 more
doaj   +1 more source

Precise Engineering of Fluorescent Covalent Organic Frameworks Nanoenzymes for Synergistic Enhancement of Monitoring and Photocatalytic Degradation of Mesotrione

open access: yesRare Metals, Volume 45, Issue 5, May 2026.
ABSTRACT The residue of mesotrione poses an increasingly serious threat to the environment and human health. Thus, it is essential to establish a platform that integrates rapid detection and efficient degradation. Covalent organic frameworks (COFs) materials have garnered significant attention owing to their designability.
Yong Xie   +3 more
wiley   +1 more source

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