Results 21 to 30 of about 9,333 (168)

Sleeve gastrectomy improved microvascular phenotypes from obesity cohort, detected with optical coherence tomography angiography 通过光学相干断层扫描血管成像检测发现袖状胃切除术改善肥胖队列的微血管表型

Journal of Diabetes, Volume 15, Issue 4, Page 313-324, April 2023., 2023
Highlights Different microvascular phenotypes were detected by noninvasive optical coherence tomography angiography (OCTA) in metabolically healthy obesity and metabolic syndrome patients. Baseline blood pressure and insulin status may be key determinants for vascular benefit from bariatric surgery.
Yaying Chen, Yanyang Liu, Lin Cong, Ailin Liu, Xiangyuan Song, Wenting Liu, Rong Hua, Qiwei Shen, Yikai Shao, Yiwen Xue, Qiyuan Yao, Yuyan Zhang   +11 more
wiley   +1 more source

Fasting and refeeding triggers specific changes in bile acid profiles and gut microbiota 禁食和再进食触发胆汁酸谱和肠道微生物群的特异性变化

Journal of Diabetes, Volume 15, Issue 2, Page 165-180, February 2023., 2023
Highlights For the first time, our study contributed a systematic evaluation of bile acid (BA) profiles in plasma, feces and liver tissue and gut microbiota changes triggered by fasting‐refeeding cycle in mice. Our work clearly demonstrated that overnight fasting leads to significant, but reversible changes in BA profiles and gut microbiota composition.
Yi Zhang, Hongyan Qi, Long Wang, Chunyan Hu, Aibo Gao, Qihan Wu, Qiaoling Wang, Huibin Lin, Banru Chen, Xingyu Wang, Shuangyuan Wang, Hong Lin, Weiqing Wang, Yufang Bi, Jiqiu Wang, Jieli Lu, Ruixin Liu   +16 more
wiley   +1 more source

Reproductive factors and metabolic syndrome among Chinese women aged 40 years and older 中国40岁及以上妇女生殖影响因素与代谢综合征

Journal of Diabetes, Volume 15, Issue 1, Page 36-46, January 2023., 2023
Highlights Reproductive variables are associated with metabolic syndrome (MetS) and its components, but the results are conflicting. In this cross‐sectional study involving 4453 women over 40, we found that reproductive variables, including menarche, pregnancy, childbirth, breastfeeding, and menopause, may play a role in modulating the risk of MetS ...
Ling Bai, Xi Yang, Ziyi Sun, Zuojie Luo, Li Li, Xinghuan Liang, Jia Zhou, Liheng Meng, Yang Peng, Yingfen Qin   +9 more
wiley   +1 more source

Association between early life famine exposure and risk of metabolic syndrome in later life 生命早期饥荒暴露与晚年代谢综合征风险之间的关联

Journal of Diabetes, Volume 14, Issue 10, Page 685-694, October 2022., 2022
Highlights In a community‐dwelling Chinese population, famine exposure in early life, especially during the fetal and childhood stages, has an association with an increased risk of metabolic syndrome (MetS) in later life, but the above findings only applied to females, not males.
Yi Zhang, Hongyan Qi, Chunyan Hu, Shuangyuan Wang, Yuanyue Zhu, Hong Lin, Lin Lin, Jie Zhang, Tiange Wang, Zhiyun Zhao, Mian Li, Yu Xu, Min Xu, Yufang Bi, Weiqing Wang, Yuhong Chen, Jieli Lu, Guang Ning   +17 more
wiley   +1 more source

Metabolomic Study on the Advanced Pancreatic Cancer Model in Nude Mouse [PDF]

, 2016
胰腺癌是一种恶性程度极高的消化道类恶性肿瘤，早期无显著病征，病人在确诊时病情基本已处于中晚期，而研究显示，直径小于2cm和1cm的胰腺癌术后5年生存率分别可达30%-60%和超过75%，远高于中晚期术后5年生存率。 本文为课题“基于核磁共振的代谢组学技术发现胰腺癌的生物标志物及早期诊断应用”的一部分。整个课题目的在于通过系统分析动物和人类胰腺癌中晚期模型代谢通道的异同点，然后通过构建动物早期胰腺癌模型，并结合中晚期动物与人类胰腺癌代谢通路的共同点 ...
李志水
core  

Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment

Rare Metals, Volume 45, Issue 2, February 2026.
ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang, Jiatong Lin, Yi Peng, Zehua Wu, Yingying Liu, Wei Duan, Qiaolin Wei, Jia‐Wei Shen, Jiang‐Xing Chen, Yong Guo   +9 more
wiley   +1 more source

Malignancy-associated metabolic profiling of human glioma cell lines using 1H NMR spectroscopy [PDF]

, 2015
胶质瘤恶性转化的原因和机制不明，给临床诊疗带来极大困难。越来越多的研究表明肿瘤恶性转化与细胞代谢紊乱密切相关，但胶质瘤恶性转化相关的细胞代谢特点目前尚不清楚。因此，探寻不同恶性程度胶质瘤细胞的代谢轮廓，将有助于开发监测胶质瘤恶性进展的非入侵式生物标志物和靶向代谢通路的治疗策略。本研究收集5种不同病理级别瘤组织来源的人脑胶质瘤细胞系（CHG5／SHG44／U118／U87／U251），其中CHG5和SHG44为WHOII级来源；U118,U87和U251为WHOIV级来源。体外培养后，首先通过侵袭能力 ...
邵巍
core  

Contrasting light demands determine the coordination of plants' non‐structural carbohydrates and economic strategy over the range of solar spectral composition

Functional Ecology, Volume 40, Issue 2, Page 534-552, February 2026.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Non‐structural carbohydrates (NSC) are critical mediators of plant adaptation to fluctuating light environments. They are tightly coordinated with plant economic strategy, that is, leaf economics spectrum (LES) and root economics spectrum (RES).
Lulu Xie, Jingran Ma, Jiaojiao Deng, Thomas Matthew Robson, Dapao Yu, Li Zhou, Qing‐Wei Wang   +6 more
wiley   +1 more source

Advances and challenges in plant spatial metabolomics research(植物空间代谢组学研究的进展与挑战)

浙江大学学报. 农业与生命科学版
Since the emergence of omics technologies, the metabolomics has been widely applied in the identification of metabolites in plants. However, the traditional metabolomics methods face limitations in uncovering the spatiotemporal distribution ...
张韵千(ZHANG Yunqian), 蔡圣冠(CAI Shengguan)   +1 more
doaj   +1 more source

The application of NMR techniques in origin characterization and adulteration identification of honey [PDF]

, 2016
随着生活条件的不断提升，人们对食品品质的要求越来越高。蜂蜜作为一种天然甜味剂，可以为人体提供丰富的营养成分。而植物来源不同，产地不同的蜂蜜成分存在差异，其中糖类、氨基酸等成分含量上的差异，会带来蜂蜜甜度，气味等性状的不同，而这些通常是蜂蜜等级的标志。此外，近几年掺假蜂蜜在市场上不断出现也给人民群众的健康和生命安全带来威胁。所以，有效地对蜂蜜进行溯源分析和掺假鉴别成为消费者和食品企业的必然要求，这既是国际科学研究的前沿，也是与人类健康和生活密切相关的重要社会问题。然而传统的鉴别方法，过于耗费人力物力 ...
郑馨
core