Results 21 to 30 of about 18,346 (122)

Endogenous/Exogenous Dual‐Responsive Bimetallic Hollow Nanozyme for Photothermal/Nanocatalysis/Immune Synergistic Tumor Therapy

open access: yesRare Metals, Volume 45, Issue 1, January 2026.
ABSTRACT Nanozymes have attracted considerable attention in cancer therapy due to their adjustable enzyme activity and high catalytic efficiency. However, they still face a major challenge from tumor metastasis. In this work, endogenous/exogenous dual‐responsive bimetallic hollow PdRu (termed HPdRu) nanozymes were prepared.
Nan‐Nan Zheng, Xin Hu, Jun‐Qing Hu
wiley   +1 more source

Developing a Linguistically Valid Japanese Version of the Chronic Pain Attribution Scale: Translation and Cultural Adaptation Process

open access: yesNeuropsychopharmacology Reports, Volume 45, Issue 4, December 2025.
This study reports the development and linguistic validation of the Japanese version of the Chronic Pain Attribution Scale. The tool captures culturally nuanced beliefs about chronic pain causes and provides a foundation for research on treatment responses in Japanese‐speaking populations.
Keiko Yamada   +8 more
wiley   +1 more source

Fcγ受体与特发性膜性肾病相关性研究进展

open access: yesZhongguo shiyan zhenduanxue, 2018
特发性膜性肾病(IMN)是一种器官特异性的自身免疫性疾病,其特征性病理特征为肾脏足细胞损伤、上皮下免疫复合物的沉积、基底膜增厚。细胞表面的IgG的受体(FcγR)是一种膜结合糖蛋白,属于免疫球蛋白超家族,是负责调控体液免疫和细胞免疫的关键免疫受体。近年来研究表明FcγR在自身免疫性疾病中起着重要作用,参与多种免疫复合物(IC)所致的肾脏疾病 ...
范卉   +4 more
doaj  

Satisfaction With Health Services During the COVID‐19 Pandemic: Results From a Population‐Based Survey in a Municipality in Southeastern Brazil

open access: yesWorld Medical &Health Policy, Volume 17, Issue 4, Page 912-920, December 2025.
ABSTRACT In Brazil, the healthcare system is based on the provision of a public system that offers free and universal services to all citizens, supplemented by private initiative. Evaluating user satisfaction plays an important role in identifying improvements and promoting organizational changes that benefit everyone involved.
Patrícia Silva Bazoni   +8 more
wiley   +1 more source

大肠杆菌类脂A及抗类脂A抗体的制备及鉴定

open access: yesZhongguo shiyan zhenduanxue, 2004
目的 比较不同剂量抗原、不同免疫途径类脂A抗体的产生。方法 应用水解法制备出大肠杆菌的类脂A作为抗原 ,分别进行皮下免疫和静脉注射免疫。结果 两种免疫方法所获得的抗血清效价相同 ,静脉免疫途径获得抗体历程时间短 ,抗原制备相对简单。结论 就获得同等效价抗类脂A抗体的方法而言 ,静脉免疫途径较皮下免疫途径简易 ...
于艳辉   +3 more
doaj  

World Association for Veterinary Dermatology Consensus Statement for Diagnosis, and Evidence‐Based Clinical Practice Guidelines for Treatment and Prevention of Canine Leishmaniosis

open access: yesVeterinary Dermatology, Volume 36, Issue 6, Page 723-787, December 2025.
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis   +9 more
wiley   +1 more source

动物园圈养野生禽类H5亚型禽流感疫苗免疫后抗体水平研究

open access: yes野生动物学报, 2013
为研究动物园圈养野生禽类高致病性禽流感疫苗免疫后的抗体水平,本文以雉鸡、缅甸鹦鹉、原鸡、蓝孔雀、白鸽为研究对象,接种H5亚型禽流感灭活油乳剂疫苗,利用禽流感血凝及血凝抑制试验,分别在首免日、免疫后21 d、30 d、60 d、120 d和180 d监测禽流感免疫抗体变化。结果表明5组禽类均在疫苗接种后产生禽流感抗体,当30 d加强免疫后,第60 d抗体达到峰值,120 d后抗体开始下降。通过研究,证实商品化疫苗对动物园圈养野生禽类有效,同时提出圈养野生禽类的高致病性禽流感免疫程序 ...
马萍   +6 more
doaj  

First report of indolent cutaneous T‐cell lymphoma in a fennec fox (Vulpes zerda)

open access: yesVeterinary Dermatology, Volume 36, Issue 5, Page 707-711, October 2025.
A 10‐year‐old fennec fox (Vulpes zerda) was presented for multifocal regions of chronic alopecia and crusting. Cutaneous lymphocytosis was diagnosed through histopathological examination and immunohistochemical investigation. Clonal rearrangement of the T‐cell receptor gamma locus supports that lymphocytosis in this case is an indolent lymphoma ...
Kristen L. Shekelle   +5 more
wiley   +1 more source

免疫固定电泳及免疫球蛋白定量在多发性骨髓瘤诊断和分型中的应用

open access: yesZhongguo shiyan zhenduanxue, 2016
目的探讨免疫固定电泳和免疫球蛋白定量在多发性骨髓瘤诊断和分型中的应用。方法采用血清蛋白电泳技术、免疫固定电泳技术、免疫比浊法对87例多发性骨髓瘤患者进行分析。结果 87例患者血清蛋白电泳77例检出M蛋白,阳性率为88.5%,免疫固定电泳均为阳性,免疫分型IgGκ29例,占33.3%;IgGλ22例,占25.3%;IgAκ10例,占11.5%;IgAλ12例,占13.8%;IgMκ4例,占4.6%;IgMλ3例,占3.4%;κ轻链2例,占2.3%;λ轻链5例,占5.7 ...
陈云峰, 葛亮, 沈建江
doaj  

The Reality of Contingency: Implications for Crisis Management

open access: yesRisk, Hazards &Crisis in Public Policy, Volume 16, Issue 3, September 2025.
ABSTRACT We live in a time of overwhelming uncertainty. Whether it is the consequences of the 2025 global trade war, the war in Ukraine, the outbreak of new pandemics, the validity of knowledge, or the possible extinction of humans as a species, the power of contingency has never been so profound.
Simon Hollis, Magnus Ekengren
wiley   +1 more source

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