World Medical &Health Policy, Volume 17, Issue 3, Page 510-528, September 2025.ABSTRACT The COVID‐19 pandemic precipitated a global emergency and governments employed various strategies to increase COVID‐19 vaccine coverage across the population, including vaccine mandates. No comparative study has evaluated the development, implementation, and structure of COVID‐19 mandatory vaccination policies in the Southeast Asia region ...
Nor Kamila Kamaruzaman +9 more
wiley +1 more source
Updated insights into the molecular pathogenesis of canine atopic dermatitis
Veterinary Dermatology, Volume 36, Issue 4, Page 375-384, August 2025.Abstract Atopic dermatitis (AD) is a common and chronic inflammatory skin disease with frequent relapses. The genomics revolution has greatly contributed and revolutionised our knowledge of human AD; understanding the molecular skin fingerprint of AD and associated pathogenic immune pathways has led to preclinical assessments of several novel ...
Frane Banovic
wiley +1 more source
The Th cell subsets analysis of syphilis patients and mechanism of Treponema pallidum infection [PDF]
, 2016 梅毒是由梅毒螺旋体引起的性传播疾病。梅毒螺旋体可侵入人体各个组织器官，引起各种临床表现。目前机体对梅毒螺旋体的免疫机制尚不清楚。本课题分别从体内和体外实验分析梅毒螺旋体引起的初始Th细胞分化，初步探讨梅毒螺旋体细胞免疫机制。我们分析32例梅毒患者外周血辅助性T细胞（Th）亚群含量变化；通过兔皮内接种模型，分析梅毒螺旋体感染后局部炎症反应中IFN-γ和IL-4mRNA的表达随时间变化情况。体内研究发现梅毒螺旋体感染后细胞免疫应答在人外周血和兔皮损中IFN-γ含量明显升高，Th1型细胞增多 ...
张巧
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Image analysis of the nuclear characteristics of emerin protein and the correlation with nuclear grooves and intranuclear cytoplasmic inclusions in lung adenocarcinoma [PDF]
, 2019 学位記番号 ...
Kobayashi, Sayaka +2 more
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Testicular fine needle aspirations cause histological injuryand immunological response in mouse testis [PDF]
, 2008 The purpose of this study was to define the histopathological change and immunological response occurring as a result of testicular fine needle aspirations (TEFNAs) in C3H/HeN mice.
Tsuboi, Hiromu
core +1 more source
N-methyl-D-aspartate receptor mediates X-irradiation-induced decrease of drebrin accumulation in dendritic spines [PDF]
, 2018 学位記番号 ...
Shuchuan, Miao +1 more
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気管支喘息患者における細胞性免疫,ガンジダ抗原に対する遅延型反応の抑制 [PDF]
, 1992 Delayed cutaneous hypersensitivity towards Candida albicans was examined in 200 patients with bronchial asthma in relation to patient age and the level of total IgE. 1.
Harada, Hideo +7 more
core +1 more source
Heat shock-induced HIKESHI protects cell viability via nuclear translocation of heat shock protein 70 [PDF]
, 2018 学位記番号 ...
Yanoma, Toru +2 more
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Establishment of An Effective System to Develop Avian Polyclonal Antibodies and Its Primary Application [PDF]
, 2016 小鼠单克隆抗体技术已成为生物医药领域不可或缺的研究工具，在疾病的诊断和治疗领域也得到广泛应用。然而，由于小鼠自身免疫系统的局限，某些抗原或表位，特别是同为哺乳动物的人体抗原在小鼠体内可能因为种属相近而不易产生好的免疫应答，给制备相应的小鼠单克隆抗体造成一定的困难。因此，有必要基于其它种属动物开发新的抗体制备技术。禽源抗体技术也称卵黄抗体技术（简称IgY技术），是用免疫原刺激禽类动物，产生相应的特异性抗体，该抗体会转运、储存在卵黄中，经特殊的提取技术，可从卵黄中获得大量特异性的多克隆抗体的一种抗体制备技术。
康雅虹
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Histological changes of human alveolar bone periosteal cell spheroids upon exposure to low-intensity pulsed ultrasound [PDF]
, 2016 我々は，イヌの実験的骨欠損部に低出力超音波パルス（LIPUS）を照射すると，歯周組織の治癒が促進されることを報告した。しかし，その詳細なメカニズムは明らかでないため，今回は，ヒト歯槽骨骨膜由来細胞（HABPCs）の細胞凝集塊(スフェロイド)を作製して LIPUS を照射し，スフェロイド内の細胞形態および骨基質タンパク発現に与える LIPUS の影響を経時的に検索した。1 日，3，7，および 14 日間，LIPUS を照射したスフェロイドに対し，トルイジンブルーを用いた組織学的検索と，抗オステオポンチン ...
川津 布美
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