Results 61 to 70 of about 4,193 (142)

Research and Application Progress of Dual-energy CT in Prostate Lesions [PDF]

open access: yes
Prostate lesions are common in middle-aged and elderly men. Dual-energy CT (DECT) can capture projection data at high and low X-ray energies in a single scan, significantly enhancing its ability to differentiate substances compared with traditional CT ...
Luyao ZHANG   +3 more
core   +1 more source

PSA、PSAD、F-PSA/PSA在前列腺癌诊断中的价值

open access: yesZhongguo shiyan zhenduanxue, 2001
目的 评价PSA、PSAD、F-PSA/PSA在Pca诊断中的价值。方法 采用放射免疫分析方法测定20例Pca和60例BPH患者血清中的PSA、PSAD、F-PSA,用ROC曲线评价它们在厌诊断中的价值。结果Pca患者血清中ISA、PSAD明显高于 BPH,F-PSA/PSA明显低于 BPH,存在统计学意义的差异(P<0.01);以 PSA>4.0μmol/L、PSAD>0.2、F-PSA /PSA<0.15,为临界值,PSA的敏感性高于 PSAD、F-PSA/PSA,而特异性、诊断指数、诊断效率 ...
邓家德, 万建新, 陈蕃
doaj  

铼-188和平阳霉素联合导向治疗前列腺癌的体外作用

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2008
[目的]探讨前列腺特异膜抗原单克隆抗体7E11C5.3介导铼-188和平阳霉素(PYM)导向治疗前列腺癌细胞系LNCaP的体外作用。[方法]以葡聚糖为中介体制备7E11C5.3-PYM偶联物,间接ELISA法测定免疫活性,2,3,5-氯化三苯基四氮唑(TTC)法测定抑菌活性。采用2-巯基乙醇直接还原法制备188Re-7E11C5.3标记物,纸层析法测定标记率和放化纯度,直线回归外推法测定免疫活性分数。四唑盐(MTT)法测定体外细胞毒作用。[结果]7E11C5.3-PYM偶联物中7E11C5 ...
张勇   +5 more
doaj  

RJUA-QA: A Comprehensive QA Dataset for Urology

open access: yes
We introduce RJUA-QA, a novel medical dataset for question answering (QA) and reasoning with clinical evidence, contributing to bridge the gap between general large language models (LLMs) and medical-specific LLM applications.
Cai, Hongbo   +16 more
core  

Interpretation on Cancer Statistics, 2024 and Comparison of Cancer Prevalence Between China and America [PDF]

open access: yes
In January 2024, Cancer Statistics, 2024 was published in CA: A Cancer Journal for Clinicians. This report estimated cancer cases and deaths in 2024 and described the secular trends of major cancers over recent decades.
Wenjing ZHAO   +3 more
core   +1 more source

Expert consensus of 177Lu-labeled PSMA radioligand therapy for clinical practice of prostate cancer (2024 edition) [PDF]

open access: yes
177Lu-labeled prostate-specific membrane antigen radioligand therapy (177Lu-PSMA-RLT) is an innovative treatment approach that precisely delivers β radiation emitted by 177Lu to prostate cancer cells, causing radiation damage to the tumor cells’ DNA and ...
Cancer Nuclear Medicine Committee of China Anti-Cancer Association, Chinese Association of Nuclear Medicine Physicians
core   +1 more source

人附睾蛋白4在前列腺疾病中的诊断效果探讨

open access: yesZhongguo shiyan zhenduanxue
目的 探讨前列腺疾病诊断中人附睾蛋白4(human epididymal protein 4,HE4)的早筛效果。方法 选取2021年6月至2022年6月张家口市第一医院收治的疑似前列腺疾病的患者共计200例,所有入组患者进行病理诊断。并以病检结果为金标准,观察HE4对前列腺疾病的诊断效能,包括敏感度,特异度,准确度指标。化学发光法测定患者HE4、前列腺血清酸性磷酸酶(prostatic serum acid phosphatase, PSAP)以及前列腺特异性抗原(prostate specific ...
董存元   +4 more
doaj  

复合型PSA与总PSA比值在前列腺癌诊断中的应用

open access: yesZhongguo shiyan zhenduanxue, 2005
目的 探讨复合型PSA(CPSA)与总PSA(TPSA)比值在前列腺癌(PCa)诊断的应用价值。方法 采用化学发光免疫分析法(CLIA)测定2 78例患者(其中PCa 6 3例,BPH2 15例)与112例正常健康体检男性的血清TPSA、CPSA水平,并计算TPSA/CPSA(C/T)比值。结果 BPH组、PCa组TPSA、CPSA水平均显著高于正常对照组(P
陈斌鸿, 陈社安
doaj  

AGR2: A New Biomarker of Cancer Diagnosis [PDF]

open access: yes, 2013
Agr2(AnTErIOr grAdIEnT-2)是一种分泌蛋白,广泛存在于前列腺、乳腺、肺和胰腺等腺体组织,并在这些腺体的肿瘤组织过量表达,与肿瘤细胞的存活、生长和转移相关。临床上,Agr2的表达与乳腺癌、前列腺癌、胰腺癌等癌症的发展和预后相关,被认为是一个很有前途的早期诊断和判定预后的标志性基因。该文就目前Agr2的研究现状,尤其是肿瘤相关的功能、机制和临床调查上的最新研究进展加以综述。AGR2 is a secreted protein and widely found in the ...
吕忠显   +3 more
core  

前列腺特异性抗原测定PCA3基因表达在前列腺癌诊断中的应用价值

open access: yesZhongguo shiyan zhenduanxue, 2017
中国前列腺癌发病率呈现为持续增长的趋势,根据流行病学调查数据显示[1],自1993年的每10万男性人口1.71人逐渐增长到了2010年每10万男性人口14.2人,年增长幅度达到了13%。根据该增长比例推算,预计到2020年,我国前列腺癌的发病率将超过40/10万人 ...
钱磊, 孙静, 陈瑞萍
doaj  

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