Results 61 to 70 of about 4,516 (129)
Research and Application Progress of Dual-energy CT in Prostate Lesions [PDF]
Prostate lesions are common in middle-aged and elderly men. Dual-energy CT (DECT) can capture projection data at high and low X-ray energies in a single scan, significantly enhancing its ability to differentiate substances compared with traditional CT ...
Luyao ZHANG +3 more
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Zhongguo shiyan zhenduanxue, 2001 目的 评价ＰＳＡ、ＰＳＡＤ、Ｆ－ＰＳＡ／ＰＳＡ在Ｐｃａ诊断中的价值。方法 采用放射免疫分析方法测定２０例Ｐｃａ和６０例ＢＰＨ患者血清中的ＰＳＡ、ＰＳＡＤ、Ｆ－ＰＳＡ，用ＲＯＣ曲线评价它们在厌诊断中的价值。结果Ｐｃａ患者血清中ＩＳＡ、ＰＳＡＤ明显高于 ＢＰＨ，Ｆ－ＰＳＡ／ＰＳＡ明显低于 ＢＰＨ，存在统计学意义的差异（Ｐ＜０．０１）；以 ＰＳＡ＞４．０μｍｏｌ／Ｌ、ＰＳＡＤ＞０．２、Ｆ－ＰＳＡ ／ＰＳＡ＜０．１５，为临界值，ＰＳＡ的敏感性高于 ＰＳＡＤ、Ｆ－ＰＳＡ／ＰＳＡ，而特异性、诊断指数、诊断效率 ...
邓家德, 万建新, 陈蕃
doaj
RJUA-QA: A Comprehensive QA Dataset for Urology
We introduce RJUA-QA, a novel medical dataset for question answering (QA) and reasoning with clinical evidence, contributing to bridge the gap between general large language models (LLMs) and medical-specific LLM applications.
Cai, Hongbo +16 more
core
Interpretation on Cancer Statistics, 2024 and Comparison of Cancer Prevalence Between China and America [PDF]
In January 2024, Cancer Statistics, 2024 was published in CA: A Cancer Journal for Clinicians. This report estimated cancer cases and deaths in 2024 and described the secular trends of major cancers over recent decades.
Wenjing ZHAO +3 more
core +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2008 [目的]探讨前列腺特异膜抗原单克隆抗体7E11C5.3介导铼-188和平阳霉素（PYM）导向治疗前列腺癌细胞系LNCaP的体外作用。[方法]以葡聚糖为中介体制备7E11C5.3-PYM偶联物，间接ELISA法测定免疫活性，2,3,5-氯化三苯基四氮唑（TTC）法测定抑菌活性。采用2-巯基乙醇直接还原法制备188Re-7E11C5.3标记物，纸层析法测定标记率和放化纯度，直线回归外推法测定免疫活性分数。四唑盐（MTT）法测定体外细胞毒作用。[结果]7E11C5.3-PYM偶联物中7E11C5 ...
张勇 +5 more
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PI-RADS 3分与4分患者中血清学指标诊断效能及联合决策模型研究
Zhongguo shiyan zhenduanxue目的探讨前列腺癌相关检验指标在多参数磁共振成像（mp-MRI）检查中前列腺影像报告和数据系统（PI-RADS）评分为3分或4分患者中的诊断效能，并构建临床决策模型以优化穿刺策略。方法回顾性分析89例接受mpMRI检查且PI-RADS评分为3分或4分、并接受经会阴途径前列腺穿刺活检的病例资料。收集患者年龄、合并症、血清学指标及病理结果。通过受试者工作特征（ROC）曲线评估各指标的诊断效能，并利用决策曲线分析（DCA）计算基于最佳截断值的穿刺模型的临床净获益。结果PI-RADS 3分与4分两组患者在年龄 ...
杨添尹, 刘娜, 张曼
doaj
Expert consensus of 177Lu-labeled PSMA radioligand therapy for clinical practice of prostate cancer (2024 edition) [PDF]
177Lu-labeled prostate-specific membrane antigen radioligand therapy (177Lu-PSMA-RLT) is an innovative treatment approach that precisely delivers β radiation emitted by 177Lu to prostate cancer cells, causing radiation damage to the tumor cells’ DNA and ...
Cancer Nuclear Medicine Committee of China Anti-Cancer Association, Chinese Association of Nuclear Medicine Physicians
core +1 more source
AGR2: A New Biomarker of Cancer Diagnosis [PDF]
, 2013 Agr2(AnTErIOr grAdIEnT-2)是一种分泌蛋白,广泛存在于前列腺、乳腺、肺和胰腺等腺体组织,并在这些腺体的肿瘤组织过量表达,与肿瘤细胞的存活、生长和转移相关。临床上,Agr2的表达与乳腺癌、前列腺癌、胰腺癌等癌症的发展和预后相关,被认为是一个很有前途的早期诊断和判定预后的标志性基因。该文就目前Agr2的研究现状,尤其是肿瘤相关的功能、机制和临床调查上的最新研究进展加以综述。AGR2 is a secreted protein and widely found in the ...
吕忠显 +3 more
core
Zhongguo shiyan zhenduanxue目的 探讨前列腺疾病诊断中人附睾蛋白4(human epididymal protein 4,HE4)的早筛效果。方法 选取2021年6月至2022年6月张家口市第一医院收治的疑似前列腺疾病的患者共计200例，所有入组患者进行病理诊断。并以病检结果为金标准，观察HE4对前列腺疾病的诊断效能，包括敏感度，特异度，准确度指标。化学发光法测定患者HE4、前列腺血清酸性磷酸酶(prostatic serum acid phosphatase, PSAP)以及前列腺特异性抗原(prostate specific ...
董存元 +4 more
doaj
Zhongguo shiyan zhenduanxue, 2005 目的 探讨复合型PSA（CPSA）与总PSA（TPSA）比值在前列腺癌（PCa）诊断的应用价值。方法 采用化学发光免疫分析法（CLIA）测定2 78例患者（其中PCa 6 3例,BPH2 15例）与112例正常健康体检男性的血清TPSA、CPSA水平,并计算TPSA/CPSA（C/T）比值。结果 BPH组、PCa组TPSA、CPSA水平均显著高于正常对照组（P
陈斌鸿, 陈社安
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