Autophagy and androgen signaling pathway in the benign prostatic hyperplasia of castrated rat caused by androgen [PDF]
, 2015 实验目的：本实验为研究雄激素诱导去势大鼠发生前列腺增生过程中雄激素作用是否与PI3K/AKt/mTOR通路有关，以及细胞自噬水平的高低能否影响雄激素诱导的去势大鼠前列腺增生水平。 研究方法：80只SD大鼠（8周龄，250±10g）随机分为4组。3组为实验组，大鼠行去势手术后给予睾酮诱导大鼠前列腺增生，实验组中两组大鼠同时分别予雷帕霉素和3-MA。分别在术后1、4、9、14、28天处死大鼠获取大鼠前列腺组织。排水法测前列腺体积，称取前列腺湿重以及计算前列腺指数。采用PCR、Westblot、HE ...
付国
core
Research and Application Progress of Dual-energy CT in Prostate Lesions [PDF]
Prostate lesions are common in middle-aged and elderly men. Dual-energy CT (DECT) can capture projection data at high and low X-ray energies in a single scan, significantly enhancing its ability to differentiate substances compared with traditional CT ...
Luyao ZHANG +3 more
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Disease-related Metabonomics Research using Ultra-performance Liquid Chromatography – Mass Spectrometry [PDF]
, 2009 代谢组学是功能基因组学和系统生物学研究的重要组成部分。作为一个发展中的代谢组学分析工具，超高效液相色谱正受到越来越多的重视。本文以UPLC/MS的代谢组学研究为中心，开展了以下几方面的工作： 我们针对8例糖尿病肾病患者、33例2型糖尿病患者和25例正常人发展了基于UPLC/MS的代谢组学研究方法。患者和正常人之间可以得到明显的区分，而且两种疾病患者都可以投影到不同的区间得到较好的区分。通过精确分子量、同位素分布、MS/MS信息和标准品对照，我们初步鉴定了亮氨酸、4-羟双氢鞘氨醇和二氢鞘氨醇等标志物 ...
张洁
core
Factors associated with depressive symptoms, anxiety symptoms, and comorbidities in the elderly population of Jiangsu province: an analysis based on data from the Elderly Psychological Care Action Project [PDF]
Objective To analyze the depressive symptoms, anxiety symptoms, and comorbidities among the elderly in Jiangsu province and their influencing factors, thus providing data support for the prevention and control of depression and anxiety in the elderly ...
Jian SU, Wencong DU, Xun WU
core +1 more source
经直肠超声检测前列腺体积结合PSA检测对于前列腺癌诊断的意义
Zhongguo shiyan zhenduanxue, 2015 目的探讨经直肠超声检测前列腺体积结合前列腺特异性抗原检测对于前列腺癌的诊断价值。方法回顾性分析我院2011年1月-2013年12月间收治的52例前列腺疾病患者的临床资料,入院后均给予经直肠超声检查,后经过前列腺穿刺活检或术后病理证实,其中有21例确诊为前列腺癌设为PCa组,中重度前列腺增生31例设为BPH组,比较两组经直肠超声检测的声像特点及其PSA水平。结果 PCa组患者前列腺体积相比于BPH患者明显减小,t=3.901 ...
胡剑, 任魁, 艾清秀, 王湘玉
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Zhongguo shiyan zhenduanxue, 2021 肾细胞癌又名肾癌,约占肾脏恶性疾病的80%-90%,是泌尿系统中发病率仅次于前列腺癌、膀胱癌的恶性肿瘤[1]。肾癌的早期临床症状较为隐匿,发病原因尚未明确[2]。因此寻找到新的生物学标志物对肾癌的诊断、治疗及预后都尤为重要[3]。本文探讨了蛋白质二硫键异构酶A3(PDIA3)在肾癌组织中的表达量,以验证其是否可以成为诊断肾癌的新候选标志物。
杨旭, 崔璨璨, 杨照微, 徐飞
doaj
Research progress on the occurrence and surgical treatment of urethral stricture after transurethral resection of prostate for benign prostatic hyperplasia [PDF]
Transurethral resection of prostate （TURP） is the main method for retreating benign prostatic hyperplasia （BPH）， and urethral stricture is the main reason for readmission after TURP. No matter what surgical method is used to treat BPH， urethral stricture
CAI Jiale, WEN Liping, HE Min
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Preparation and Stability Evaluation of Pumpkin Seed Oil Microcapsules Using Pumpkin Seed Protein-Modified Flaxseed Gum as Wall Material [PDF]
Using pumpkin seed oil (PSO) as the core material, pumpkin seed protein nanoparticles (PSP) and modified flaxseed gum (MFG) as the wall materials of microcapsules, pumpkin seed oil microcapsules were prepared by freeze-drying method through different ...
Hongbin WU, Zhanxia LIU
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Zhongguo shiyan zhenduanxue, 2013 慢性前列腺炎（chronic prostatitis,CP）是成年男性常见的泌尿系统感染性疾病病之一,近年来,CP的发病率呈现不断增高的趋势,严重地影响了患者的生活质量[1]。由于对CP缺乏深入全面的了解和研,到目前为止,对CP的发病机理仍然不是很清楚[2]。故了解CP病原体的感染、分布规律、及对药物的敏感情况,对临床治疗有着重要的指导意义。我们对2009年6月至2011年12月434例在我院门诊就诊的慢性细菌性前列腺炎患者的前列腺液病原菌培养结果和药敏试验数据进行了回顾性分析,
李春光, 王松岩, 陈岐辉
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