Results 41 to 50 of about 29,509 (170)
Rare Metals, Volume 45, Issue 3, March 2026.ABSTRACT Lung cancer remains the leading cause of cancer‐related deaths worldwide, yet immune checkpoint blockade (ICB) is often compromised by an immunosuppressive tumor microenvironment (TME) with acidosis, hypoxia, and poor T cell infiltration. Here, we develop a TME‐responsive nanoplatform (MgH2@Lip/PD‐L1) that couples hydrogen gas therapy with PD ...
Xuyu Gu +5 more
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2008 【目的】 探讨新辅助化疗对Ⅰb2 ～ Ⅲb期宫颈癌的近期临床疗效? 【方法】 选择我院2003年6月～2007年9月收治的经病理确诊的28例Ⅰb2 ～ Ⅲb期宫颈癌患者,动脉介入化疗18例,化疗方案:卡铂(300 mg/m2)+博来霉素(45 mg);静脉化疗10例,化疗方案:卡铂(AUC 6)+5*9鄄FU(4 000 mg/m2 > 96 h)?化疗10 ～ 14 d重新评估,化疗2 ～ 3周行广泛全子宫切除术+盆腔淋巴结清扫术,观察近期临床疗效?【结果】 化疗有效率82.1%(23/28 ...
温国群
doaj
Involvement of Abnormal MicroRNA Expression in the Mechanism of Drug Resistance with Acute Myeloid Leukemia [PDF]
, 2016 目的：分析miRNA-98的表达异常在急性髓系白血病化疗耐药机制的作用，通过靶向过表达miRNA-98的表达水平探讨以miRNA-98为靶点增加化疗药物敏感性的可能性并分析其可能作用的机制。评价异常表达的血清miRNA-155是否可作为急性髓系白血病的预后标志。 方法：离体实验中，采用qRT-PCR方法检测K562和其耐药株K562/A02中miR-98、E2F1基因表达情况。通过瞬时转染miR-98mimic处理耐药细胞K562/A0248h后，通过qRT-PCR法检测miR-98表达情况；通过qRT-
黄英丹
core
World Medical &Health Policy, Volume 18, Issue 1, March 2026.ABSTRACT Population aging is a problem that countries around the globe are facing; it comes with complex healthcare needs. Different countries take different approaches to solving these issues. In the United States, proposed legislation related to hospice and palliative care emerged from a history of hospice fraud and specialty physician shortages.
Edith‐Marie Green
wiley +1 more source
Nursing care of a case with hypertension induced by paclitaxel chemotherapy
Huli yanjiu, 2004 为探讨紫杉醇化疗毒副反应之一高血压的护理 ,对门诊接受紫杉醇化疗的病人在化疗期间加强心理护理和生命体征监测 ,去除焦虑因素 ,并对化疗过程中发生高血压的病人给予对症处理并严密观察 ,使病人顺利完成了化疗。
高瑞珍 +3 more
doaj
Down-regulation of GRP78 Enhances Chemotherapy Sensitivity to VP-16 in Lung Adenocarcinoma [PDF]
, 2009 Background and objective GRP78, a member of GRPs, plays a critical role in chemotherapy resistance in some cancers. To investigate the relationship between the expression of GRP78 and resistance to anti-cancer drug VP-16 in vitro in lung adenocarcinoma ...
Li JIANG +3 more
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World Medical &Health Policy, Volume 18, Issue 1, March 2026.ABSTRACT This systematic review examines the digital health interventions for inclusive and equitable solutions for transforming healthcare access and delivery in Nepal. The research focuses on improving digital health accessibility among marginalized and rural populations of Nepal.
Manoj Kumar Dahal, Gary L. Kreps
wiley +1 more source
BSD2000 Deep Hyperthermia Combined with Chemotherapy of PT regimen in Patients with Non-small Cell Lung Cancer [PDF]
, 2010 Background and objective The aim of this study is to determine the short-term efficacy, toxicity and the rate of life-quality improvement of BSD2000 deep hyperthermia combined with chemotherapy of PT regimen in patients with non-small cell lung cancer ...
Jun ZHAO, Mengxiang YANG, Yanwen WANG
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A Tale of Two Programs? Stigma and Administrative Burdens in CHIP and Medicaid
World Medical &Health Policy, Volume 18, Issue 1, March 2026.ABSTRACT One contributing factor to undersubscriptions is administrative burdens. To explore whether program stigma affects attitudes about administrative burdens, a survey (N = 2204) was fielded to assess differences in attitudes about seven policies decreasing administrative burdens and two policies increasing administrative burdens.
Simon F. Haeder
wiley +1 more source
Novel Manganese Dioxide Nanoparticles Enhance Chemotherapy Response by Priming Tumor-Associated Macrophages toward M1-like Phenotype and Attenuating Tumor Hypoxia [PDF]
, 2016 缺血乏氧是肿瘤微环境的重要特征之一，肿瘤的缺血乏氧不仅促进了肿瘤细胞的侵袭转移，同时还增强肿瘤对化疗药物的耐药性。肿瘤相关巨噬细胞（Tumor-associatedmacrophages，TAMs）浸润在肿瘤微环境之中，通常在肿瘤缺血乏氧区域富集。肿瘤相关巨噬细胞作为肿瘤微环境的重要功能细胞，其在肿瘤细胞的增殖、侵袭、转移、化疗耐药等肿瘤进展的各个阶段均发挥着重要作用。鉴于此，我们提出一种新型的肿瘤治疗策略，以期改变肿瘤微环境的同时，增强实体瘤对化学治疗的疗效 ...
宋曼莉
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