Results 21 to 30 of about 29,509 (170)

小剂量化疗与手术治疗儿童孤立性骨嗜酸性肉芽肿的效果比较

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2017
【目的】探讨小剂量化疗、手术及手术加术后辅助小剂量化疗这三种不同的方法在儿童孤立性骨嗜酸性肉芽肿 (SBL-EG)治疗上的有效性及可行性。【方法】回顾性分析了149例SBL-EG的儿童患者,其中86例接受小剂量化疗,33例行 手术治疗,30例接受手术及术后辅助小剂量化疗。比较三组患者的住院时间、症状缓解时间、恢复时间、治疗费用、并发 症及无复发生存时间(RFS)。【结果】小剂量化疗组的住院时间、症状缓解时间、恢复时间及治疗费用均低于手术或手术加 化疗组(P < 0.05 ...
利洪艺   +6 more
doaj  

The role of hedgehog pathway and autophagy in the mechanism of acquired chemoresistance in multiple myeloma [PDF]

open access: yes, 2015
在多发性骨髓瘤的临床治疗中,化疗耐药现象仍然是治疗失败的主要原因之一。为了更好地了解多发性骨髓瘤的化疗耐药性及相关的机制,我们建立了阿霉素(doxorubicin,DOX)耐药的细胞系多发性骨髓瘤细胞系RPMI8226/R(doxorubicin-resistantcellline),DOX对8226/R的半数抑制率(IC50)是对DOX敏感的细胞系RPMI8226/S(chemosensitivecellline)的5~6倍。我们发现在多发性骨髓瘤耐药性的诱导过程中存在Hedgehog(Hh ...
黄潇
core  

American Society of Clinical Oncology Clinical Practice Guideline Update on Chemotherapy for Stage IV Non–Small-Cell Lung Cancer [PDF]

open access: yes, 2009
The purpose of this article is to provide updated recommendations for the treatment of patients with stage IV non-small-cell lung cancer. A literature search identified relevant randomized trials published since 2002.
AZZOLI, Christopher G   +21 more
core   +1 more source

A Novel Topical Emollient Plus for Canine Atopic Dermatitis: A Clinical Trial Assessing Efficacy and User Acceptance

open access: yesVeterinary Dermatology, Volume 37, Issue 2, Page 293-305, April 2026.
Background: Canine atopic dermatitis (cAD) is a common, chronic skin condition characterised by epidermal barrier dysfunction, immune dysregulation and cutaneous dysbiosis. While “emollient plus” formulations are widely used in human atopic dermatitis, their role in cAD remains underexplored. Hypothesis/Objectives: To evaluate the clinical efficacy and
Beatriz Fernandes   +8 more
wiley   +1 more source

Ib2-IIa期巨块型宫颈癌热疗联合同步放化疗与同步放化疗的疗效比较

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2016
【目的】 比较早期巨块型宫颈癌腹盆腔深部热疗联合同步放化疗和同步放化疗的疗效和安全性之间的差异。【方法】 收集2005年3月16日至2009年5月20日经中山大学附属第五医院治疗的ⅠB2期和巨块型ⅡA期的宫颈癌82例,随机分为腹盆腔热疗加同步放化疗组(42例)和同步放化疗组(40例)。两组放化疗方案一致:盆腔外照射(30Gy/15F)+腔内放疗(A点剂量36Gy/6F),同期静脉TP方案化疗2周期。热放化疗组采用区域深部热疗,2次/周,每次60 min,每次热疗均在放疗前1h内进行。【结果 ...
徐西伟
doaj  

Clinical Observation of Erlotinib in the Treatment of Advanced Non-small Cell Lung Cancer: A Report of 92 Eases [PDF]

open access: yes, 2009
Background and objective Erlotinib, a selective inhibitor of epidermal growth factor receptor tyrosine kinase, has been approved effective in local advanced or metastatic non-small cell lung cancer (NSCLC).
Aiqin GU   +5 more
core  

Europeanization and Health Policy in the European Union During Covid‐19 Pandemic: The Case of Greece

open access: yesEuropean Policy Analysis, Volume 12, Issue 2, Spring 2026.
ABSTRACT The main purpose of this paper is to study and evaluate the efforts to respond to the covid‐19 pandemic in the EU and Greece, and to understand the capacity of the Greek health system to deal with such crises. The main questions we are called to answer are: What initiatives have been developed at EU level to address the covid‐19 pandemic? Have
Georgios Maris, Foteini Koulouri
wiley   +1 more source

非小细胞肺癌患者化疗前后血清VEGF/血小板数和TGF-β1检测的临床意义

open access: yesZhongguo shiyan zhenduanxue, 2017
目的探讨非小细胞肺癌(NSCLC)患者化疗前后血清VEGF/血小板数和TGF-β1浓度的变化,探讨两者在病情监测中的临床价值。方法 72例NSCLC患者化疗前采用酶联免疫法测定血清VEGF/血小板数和TGF-β1浓度,化疗采用GP方案,连用2周期,治疗结束后1周再次测定血清VEGF/血小板数和TGF-β1浓度,并行胸部CT检查,根据CT结果分为化疗有效组(完全缓解+部分缓解)和无效组(病情稳定+疾病进展),组间比较采用t检验 ...
顾涛   +6 more
doaj  

Effect of Ciji Hua’ai Baosheng Formula on tumor microvessel density and pathological angiogenesis factors of mice receiving chemotherapy for the treatment of H22 hepatocellular carcinoma [PDF]

open access: yes, 2016
研究目的: 研究及证实慈济化癌保生方(CijiHua’aiBaoshengFormula,CHBF)对肝癌H22荷瘤小鼠化疗后肿瘤微血管的影响。通过观察小鼠一般生存状况、测量体重、瘤重和计算抑瘤率,观察肿瘤微血管密度(microvesseldensity,MVD)以及对血清与肿瘤组织血管内皮生长因子(vascularendothelialgrowthfactor,VEGF)、VEGF受体-含激酶插入结构域的受体(kinaseinsertdomain-containingreceptor,KDR ...
赵心悦
core  

Investigating Drivers of Tiger Bone Glue Consumption in Vietnam 调查越南虎骨胶消费的驱动因素 Điều Tra Nguyên Nhân Dẫn Đến Tình Trạng Tiêu Thụ Cao Hổ Cốt Tại Việt Nam

open access: yesIntegrative Conservation, Volume 5, Issue 1, Page 115-124, March 2026.
We found the estimated use of tiger bone glue within the last 12 months to be 6.9%. We found a stated motivation of taking TBG to improve health, and by the suggestion of one's social group. We suggest reducing the acceptability of TBG as medicine and encouraging non‐animal‐based medicinal alternatives.
Elizabeth Oneita Davis   +5 more
wiley   +1 more source

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