Results 21 to 30 of about 1,258,759 (164)
ABSTRACT Esophageal squamous cell carcinoma (ESCC) remains associated with frequent local recurrence and distant metastasis despite advances in radiochemotherapy and immunotherapy, highlighting the need for therapeutic strategies that improve both local tumor control and systemic antitumor immune responses.
Dongdong Wang +7 more
wiley +1 more source
ABSTRACT Confrontational violence still puts catastrophic burdens on children, with 2024 being the highest recorded levels of displacement, malnutrition, injury, and deprivation in contemporary humanitarian history. Children's surgical care is still grossly underrepresented in health responses worldwide in the prevention of avoidable deaths and long ...
Gaurav Chanderprakash Mittal +4 more
wiley +1 more source
ABSTRACT The integration of artificial intelligence (AI) in healthcare is rapidly evolving, offering immense potential to transform service delivery, diagnostics, and health systems governance. However, Sub‐Saharan Africa faces significant readiness challenges due to limited infrastructure, capacity gaps, and fragmented digital strategies.
Said Baadel +3 more
wiley +1 more source
ABSTRACT The regeneration of osteoporotic bone defects is severely hampered by compromised endogenous healing capacity, demanding advanced strategies that actively orchestrate pro‐osteogenic microenvironments. Here, we report an integrated, self‐powered osteo‐regenerative system that uniquely leverages a dual ultrasound‐responsive piezoelectric ...
Bing Tan +6 more
wiley +1 more source
本研究自1985年4月至1991年8月对25例卵巢癌患者应用顺铂腹腔化疗为主,配合其他药物全身化疗,同时静脉注射硫代硫酸钠,无1例发生肾脏中毒。3例病人用顺铂腹腔化疗1小时组织铂的总浓度比血清升高17.3~199.3倍,并发现卵巢癌Ⅱ期中有6/12例能存活5年,其存活率为50.0%,6例死亡占总数的24.0%。167个疗程中,因毒性反应而延期化疗者有26个疗程占15.6%
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ABSTRACT Esophageal cancer is the seventh leading cause of cancer death, and the energy depletion in cancer cells can be achieved through synergistic therapy. The integration of sonodynamic therapy and chemotherapy offers a promising comprehensive treatment strategy for esophageal cancer.
Mengya Li +4 more
wiley +1 more source
ABSTRACT Due to their exceptional porosity, structural versatility, and modular coordination chemistry, metal–organic frameworks (MOFs) have emerged as versatile platforms for targeted drug delivery. These structures enable fine‐tuning of pore size, surface activity, and framework stability for the encapsulation of a broad range of therapeutics ...
Rui Hua +9 more
wiley +1 more source
随着我国医疗保险制度的建立健全,形成了城镇职工基本医疗保险、新型农村合作医疗和城镇居民医疗保险三种各自运行的保险制度,造成了我国医疗保险领域碎片化的现实。本文通过探讨碎片化的原因、危害 ...
梁晓庆
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ABSTRACT Infected bone defects represent a dual therapeutic challenge demanding concurrent infection inhibition and osteogenesis promotion. Systemic antibiotic administration is taken as a classical treatment protocol but often yields inadequate local antibiotic concentrations and delayed bone repair.
Xucai Wang +8 more
wiley +1 more source
较早期乳腺癌的治疗,公认以手术切除为主要治疗手段,因为它有较好的治疗效果,但对于一些病情较晚不宜于立即手术或放射治疗(如肿瘤巨大)的病人,以及术后局部大面积复发或有远处转移的病人,应如何治疗?这是急待我们去解决的一个大问题。仅从本院10年间外科治疗乳腺癌1,101例中,便有114例(10.6%)局部复发,360例(33.5%)发生远处转移。近年来,在同道们的努力下,运用细胞动力学的原理,设计出各种联合化疗的方案,为解决上述问题向前跨进了一大步。本文结合国产化疗药物的供应情况,设计应用长春新硷、噻替派 ...
刘广森
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