Results 11 to 20 of about 29,104 (123)
ABSTRACT Surface‐enhanced Raman scattering (SERS) has emerged as a highly sensitive and specific technique for tumor imaging, owing to its narrow spectral features, resistance to photobleaching, and capability for multiplexed detection. However, its clinical translation remains limited by poor tissue penetration and the absence of intrinsic anatomical ...
Xinyu Miao +7 more
wiley +1 more source
Chemotherapy is a common treatment for cancer, but the impact of side effects on the quality of life of patients is also the main problem that needs attention.
MEI Yuwei (梅雨薇) +4 more
doaj +1 more source
Engineering Photothermal Nanoplatforms for Multimodal Theranostics and Biosensing
ABSTRACT Photothermal platforms bridge materials science and biomedicine, emerging as a transformative frontier in biomedical applications. They offer spatiotemporally precise, noninvasive modalities with cell‐type‐independent efficacy for treating a range of diseases.
Xiao Han +3 more
wiley +1 more source
ABSTRACT Gram‐negative (G−) bacterial infections, fueled by intrinsic antibiotic resistance stemming from their unique outer membrane architecture, pose a critical global clinical challenge. This study introduces a pioneering dual‐enzyme‐mimetic nanotherapy based on NaYbF4 nanoparticles (NaYbF4 NPs) that achieves synergistic antibacterial and anti ...
Yuxiang Zhang +6 more
wiley +1 more source
ABSTRACT Calcium overload‐induced immunogenic cell death (ICD) holds great potential in antitumor immunotherapy, and it is a critical strategy for regulating multiple intracellular Ca2+ channels through inhibiting the endogenous Ca2+ efflux and promoting the exogenous Ca2+ influx.
Xingguo Xu +9 more
wiley +1 more source
目的观察化肝汤1号对酒精性肝纤维化转化生长因子β1和透明质酸水平的影响。方法对临床确诊的60例肝纤维化患者,随机单盲分为治疗组和对照组,每组30人,治疗组用自制方剂化肝汤1号治疗,对照组用凯西莱治疗,疗程12周。结果 TGFβ1变化,治疗组治疗前为164.83±6.50,治疗后为119.70±5.14,对照组治疗前为162.07±4.55,治疗后为132.07±4.44,治疗组与对照组治疗前后比较 ...
郝彦开 +4 more
doaj
ABSTRACT Pyritum can eliminate blood stasis and promote the healing of muscles and bones, which has been used as a traditional mineral medicine in China for thousands of years. However, the mechanisms of action and processing methods of Pyritum were not illustrated.
Mingxia Li +8 more
wiley +1 more source
【目的】探讨小剂量化疗、手术及手术加术后辅助小剂量化疗这三种不同的方法在儿童孤立性骨嗜酸性肉芽肿 (SBL-EG)治疗上的有效性及可行性。【方法】回顾性分析了149例SBL-EG的儿童患者,其中86例接受小剂量化疗,33例行 手术治疗,30例接受手术及术后辅助小剂量化疗。比较三组患者的住院时间、症状缓解时间、恢复时间、治疗费用、并发 症及无复发生存时间(RFS)。【结果】小剂量化疗组的住院时间、症状缓解时间、恢复时间及治疗费用均低于手术或手术加 化疗组(P < 0.05 ...
利洪艺 +6 more
doaj
ABSTRACT Esophageal squamous cell carcinoma (ESCC) remains associated with frequent local recurrence and distant metastasis despite advances in radiochemotherapy and immunotherapy, highlighting the need for therapeutic strategies that improve both local tumor control and systemic antitumor immune responses.
Dongdong Wang +7 more
wiley +1 more source
非小细胞肺癌患者化疗前后血清VEGF/血小板数和TGF-β1检测的临床意义
目的探讨非小细胞肺癌(NSCLC)患者化疗前后血清VEGF/血小板数和TGF-β1浓度的变化,探讨两者在病情监测中的临床价值。方法 72例NSCLC患者化疗前采用酶联免疫法测定血清VEGF/血小板数和TGF-β1浓度,化疗采用GP方案,连用2周期,治疗结束后1周再次测定血清VEGF/血小板数和TGF-β1浓度,并行胸部CT检查,根据CT结果分为化疗有效组(完全缓解+部分缓解)和无效组(病情稳定+疾病进展),组间比较采用t检验 ...
顾涛 +6 more
doaj

