[Traditional Chinese medicine for regulating glycolysis to remodel the tumor immune microenvironment: research progress and future prospects]. [PDF]
He S +8 more
europepmc +1 more source
中国南方地区人群FCGR2A基因多态性与强直性脊柱炎的相关性
【目的】 验证中国南方地区人群的FCGR2A基因多态性与强直性脊柱炎(AS)易感性是否相关。【方法】 共纳入350例AS患者及295例健康志愿者,采用盐析法全血中抽提样本基因组DNA,分别在患者及健康志愿者中随机抽取58例病人和90例对照者,采用外显子测序法筛选FCGR2A基因单核苷酸多态性(SNP),然后针对筛选出来的SNP 在剩余的292例患者及205例健康志愿者中采用飞行质谱方法进行验证。【结果】 通过外显子测序,一共在FCGR2A基因外显子区域筛选出了7个SNP位点,其中有5个SNP ...
doaj
[Research progress on mechanisms and clinical management of comorbid constipation in children with autism spectrum disorder]. [PDF]
Ding JJ, DU DY, Li P.
europepmc +1 more source
[Research progress of molecular imprinting technology in the field of disease diagnosis and therapy]. [PDF]
Zhu R, Cai GP, Zheng HJ, Jia Q.
europepmc +1 more source
【目的】 SLC33A1基因已被报道是我国北方一个HSP家系的致病基因,但研究未发现在欧洲的HSP患者中有该基因的突变。本研究的目的是检测SLC33A1是否为中国南方人群中遗传性痉挛性截瘫患者的致病性基因之一。【方法】 对收集到的70例中国南方散发遗传性痉挛性截瘫的患者,提取基因组DNA,并进行SLC33A1基因所有编码外显子及外显子-内含子交界区域的直接测序;鉴定所发现的遗传变异,并同我们所收集到的57例无血缘关系的正常人进行比对,以及生物信息学分析。【结果】我们只发现 ...
doaj
[Comprehensive analytical chemistry experiment: analysis of non-covalent interactions between double-stranded deoxyribonucleic acid and a natural drug by electrospray ionization mass spectrometry]. [PDF]
Ma L, Wang YH, Yuan YL, Wang SS.
europepmc +1 more source
[Research progress on lactylation modification in pathogenesis of osteoarthritis]. [PDF]
Wu Y +7 more
europepmc +1 more source
[Correlation analysis of cell-free DNA in gingival crevicular fluid with periodontal clinical indicators and cyclic guanosine phosphate-adenosine phosphate synthase-stimulator of interferon genes signaling pathway]. [PDF]
Chen L, Zhu X, Zhou J, Li J, Zhao L.
europepmc +1 more source
[Resistance to thyroid hormone syndrome with developmental disorders in two children]. [PDF]
Liao LY, Li XF, Zhang XX.
europepmc +1 more source

