基因多态性 - Open Access .click

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Zhongshan Daxue xuebao. Yixue kexue ban, 2004
【目的】研究血管紧张素转换酶(ACE)基因插入/缺失(ID)多态性与血浆PAI-1活性的关系。【方法】用PCR方法扩增93例心肌梗死患者及87例健康体检者ACE基因特异性片段,同时应用发色底物法测定PAI-1活性。【结果】①心肌梗死组ACEDD基因型频率32.3%和D等位基因频率54.3%,高于对照组12.6%和37.4 ...
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[Effect of interleukin-17 gene polymorphism on susceptibility to cow's milk protein allergy in infants and its association with gut microbiota]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Hao WY, Zhu C, Lu S, Wang H.
europepmc +1 more source

甘肃地区人群雌激素受体α-29位基因多态性与HBV感染转归的关系

, 2014
ZHOU Ning
openalex +2 more sources

Correlation between polymorphisms of SIRT2 gene and renal injury in patients with type 2 diabetes mellitus. [PDF]

Zhong Nan Da Xue Xue Bao Yi Xue Ban
Wu S, Yi B, Dai Y, Liao X, Peng J, Li A.
europepmc +1 more source

中国南方汉族人群9个STR基因座多态性分析

Zhongshan Daxue xuebao. Yixue kexue ban, 2009
【目的】分析中国南方汉族人群9个STR基因座的遗传多态性65377; 【方法】用STR_Typer_10_v1荧光标记试剂盒,对1 619例中国南方汉族无关个体的9个STR基因座(D11S2368,D12S391,D13S325 D18S1364,D22-GATA198B05,D6S1043,D2S1772,D7S3048,D8S1132)进行扩增,用AB公司3100遗传分析仪和GeneMapper 3.1v软件作STR分型,用PowerState V12 ...
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[Effects of MTHFR and GGH gene polymorphisms on plasma concentrations and toxicity following high-dose methotrexate therapy in children with acute lymphoblastic leukemia]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Teng LX +13 more
europepmc +1 more source

Chronic inflammation, the tumor microenvironment and carcinogenesis [PDF]

, 2009
Shuiping Tu, Tamas A. Gonda, Timothy C. Wang +2 more
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HPA3和传统危险因素在急性心肌梗死的交互作用

Zhongshan Daxue xuebao. Yixue kexue ban, 2013
【目的】探讨人类血小板抗原(HPA3)基因多态性与传统危险因素在急性心肌梗死(AMI)的交互作用?【方法】选择215例AMI患者和210例健康体检者作为研究对象,采用序列特异性引物-多聚酶链反应(SSP-PCR)技术扩增目的基因,进行HPA基因分型,分析其在AMI中的危险因素,使用叉生分析法分析HPA3基因与传统危险因素在AMI中的交互作用?【结果】 ①HPA3基因多态性在AMI组和对照组的分布差异无统计学意义(P > 0.05);②HPA3b等位基因与年龄≤60岁对AMI发病不存在交互作用(OR =
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[Maternal MTR gene polymorphisms and their interactions with periconceptional folic acid supplementation in relation to offspring ventricular septal defects]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Ruan XR +7 more
europepmc +1 more source

ＮＡＤＰＨ氧化酶ｐ２２ｐｈｏｘ亚基基因Ｈｉｓ７２Ｔｙｒ与脂联素基因启动子－１１３９１Ｇ／Ａ多态性的交互作用以及与大肠癌及其分化程度的关系

Zhongshan Daxue xuebao. Yixue kexue ban, 2016
摘要：【目的】探讨烟酰胺腺嘌呤二核苷酸磷酸（ＮＡＤＰＨ）氧化酶ｐ２２ｐｈｏｘ亚基基因Ｈｉｓ７２Ｔｙｒ与脂联素基因启动子－１１３９１Ｇ／Ａ多态性的交互作用以及与大肠癌及其分化程度的关系。【方法】选择我院２００９年７月至２０１４年１２月收治的大肠癌患者６６８例，分为高分化组、中分化组、低分化组、未分化组各１６２例，以１６２例健康体检者作为对照组，各组在年龄、性别、民族、籍贯和生活习惯方面无显著性差异，以上述各组患者的外周血白细胞为样本，利用聚合酶链反应－限制性片段长度多态性（ＰＣＲ－ＲＦＬＰ ...
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