Results 11 to 20 of about 1,459,652 (163)

肾素-血管紧张素系统基因多态性与慢性心力衰竭的关系 [PDF]

Zhongshan Daxue xuebao. Yixue kexue ban, 2006
[目的]探讨中国南方汉族人群中,血管紧张素转换酶（ACE）及血管紧张素原（AGT）双基因多态性与慢性心力衰竭发病的关系.[方法]用聚合酶链反应及限制性片段长度多态性技术检测111例慢性心力衰竭患者和110例健康者的ACE基因I/D及AGT基因M235T的多态性.[结果]①慢性心力衰竭组DD基因型与D等位基因的频率均高于对照组.DD基因型0.468比0.227,P＜0.01;D等位基因0.667比0.436,P＜0.01.②AGT基因M235T多态性在慢性心力衰竭组及对照组的分布无统计学差异 ...
doaj   +1 more source

汉族人群Y染色体多拷贝基因座DYS464遗传多态性 [PDF]

Zhongshan Daxue xuebao. Yixue kexue ban, 2006
【目的】 研究Y染色体多拷贝基因座DYS464遗传多态性在汉族群体中的分布规律。【方法】 选择106例汉族无亲缘关系男性个体作为研究对象，荧光标记引物PCR扩增DYS464基因座片段，ABl377自动测序仪上变性聚丙烯酰胺凝胶电泳分析PCR产物，并对不同重复序列分别测序。【结果】 DYS464基因座在106例汉族男性无关个体中发现有8种片段。变异11～18次。根据其中任意4种片段的组合，即片段大小和峰高的比率来命名等位基因，E-型命名方法，观察到61种等位基因，其中36种等位基因只出现1次 ...
黄艳梅, 区敬华, 朱伟锋, 曾艳红, 伍新尧   +4 more
doaj   +1 more source

Survivin基因启动子区-31C/G多态性与散发性 结直肠癌遗传易感性的关系

Zhongshan Daxue xuebao. Yixue kexue ban, 2010
【目的】 探讨生存素Survivin基因启动子区-31C/G单核苷酸多态性与中国华南地区散发性结直肠癌(CRC)遗传易感性的关系65377; 【方法】 采用聚合酶链反应-限制性片段长度多态性法(PCR-RFLP)检测华南地区711例健康人和702例CRC的Survivin基因-31C/G位点单核苷酸多态性65377;【结果】 结直肠癌患者CC基因型的频率明显高于对照人群(36.35% vs.
doaj   +1 more source

遗传性多发性骨软骨瘤致病基因EXT1和EXT2的多态性研究

Zhongshan Daxue xuebao. Yixue kexue ban, 2011
【目的】研究EXT1与EXT2基因在我国南方正常人及致病性突变已明确的遗传性多发性骨软骨瘤病人中的多态性。【方法】 选取50例中国南方健康汉族个体及13例致病突变已明确的遗传性多发性骨软骨瘤病人，提取基因组DNA，对包含5’UTR区、编码区、外显子-内含子交界区及3’UTR区的PCR产物进行直接测序。 鉴定基因内的遗传变异，并将结果和国际数据库中的数据进行对比。【结果】 在所有研究对象中共发现15个不同的EXT1基因的单核苷酸多态性(SNPs)：3个在编码区，为同义突变，11个在内含子区，1个在3 ...
doaj   +1 more source

Organ‐specific ozone and nitrogen legacies strengthen substrate control over litter decomposition

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Elevated tropospheric ozone (O3) and nitrogen (N) deposition are concurrent atmospheric changes that strongly influence terrestrial carbon cycling, yet their combined effects on below‐ground decomposition remain poorly understood.
Xiaofan Hou, Pin Li, Yuqian Sun, Chenhan Ma, Yushu Tian, Qiannan Lin, Yun Li, Lijuan Yin, Dongmei Zhang   +8 more
wiley   +1 more source

Alleviation of phosphorus rather than nitrogen limitation driven by permafrost and landscape effects on Dahurian larch forests

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Permafrost thaw is reshaping nutrient dynamics in boreal forests, but its impacts on tree nutrient limitation and functional strategies remain poorly understood. Clarifying these responses is crucial for predicting the response of boreal forests to climate change.
Qiyue Fu, Liang Shi, Zhaopeng Song, Boyi Liang, Honglin He, Kun Yang, Weihua Zhang, Lisha Lyu, Anatoly S. Prokushkin, Hongyan Liu   +9 more
wiley   +1 more source

Inferring alternative ecosystem states with field survey data

Methods in Ecology and Evolution, EarlyView.
Abstract Many ecosystems potentially exhibit alternative stable states, where distinct states can coexist under identical environmental conditions. While simulation models have generated key hypotheses in alternative stable states theory, they often rely on scale‐free parameters disconnected from real ecosystems.
Ning Chen, Xiaoxue Dong, Xinwei Li, Lei Huang, Heng Huang, Changjia Li, Yanchuang Zhao, Chi Xu, Miaojun Ma, Zak Ratajczak, Changming Zhao   +10 more
wiley   +1 more source

Advancing conservation breeding programs for marine invertebrates

Conservation Biology, EarlyView.
Abstract In the face of ecosystem change and biodiversity loss caused by climate change and other stressors, conservation breeding, or captive breeding, with the aim of reintroduction for wild population recovery, is an emerging tool for preventing species’ extinction and rehabilitating ecosystems.
Elora H. López‐Nandam, Bart Shepherd, Kylie Lev, Rebecca Albright   +3 more
wiley   +1 more source

Centering geospatial data uncertainty and the potential for injustice in pastoralist rangeland conservation prioritization

Conservation Biology, EarlyView.
Abstract Procedural, distributional, recognitional, and epistemic justice aspects of conservation interventions are well documented in contexts where pastoralism is a key livelihood and way of life. Geospatial analyses and representations of wildlife conservation and restoration that are increasingly applied in pastoralist rangeland socioecological ...
Ryan R. Unks
wiley   +1 more source

Assessing differences among elasmobranch nurseries to aid conservation based on a genomics framework

Conservation Biology, EarlyView.
Abstract Elasmobranch nurseries often differ in environmental conditions, demographics, and use patterns. These differences affect the distribution of genetic variation among nurseries. However, conservation and management strategies often fail to account for such differences because they are difficult to characterize.
Dominic G. Swift, Amanda M. Barker, William B. Driggers III, Bryan S. Frazier, Douglas H. Adams, James J. Gelsleichter, Dana M. Bethea, Bethany M. Deacy, David S. Portnoy   +8 more
wiley   +1 more source