Results 51 to 60 of about 25,949 (219)

The preliminary study on the relationship of PAHs contamination and metabolic enzyme gene polymorphisms and adverse pregnancy outcomes [PDF]

open access: yes, 2011
目的通过流行病学调查,掌握厦门地区妊娠妇女妊娠结局分布情况,并探讨多环芳烃污染等环境对妊娠结局的影响,结合多环芳烃代谢酶基因多态性分析,评价多环芳烃暴露对胎儿健康的危害。 方法利用问卷形式收集804例孕妇流行病学资料,以了解环境因素对妊娠妇女妊娠结局的影响。同时采用气相串联质谱(GC-MS)技术测定73例孕妇外周静脉血、新生儿脐带血中多环芳烃含量,同时应用聚合酶链反应一限制性片段长度多态性(PCR-RFLP)技术分析多环芳烃代谢酶基因多态性,以分析多环芳烃暴露对胎儿健康的危害。 结果 1 ...
杨帆
core  

Correlation of Genetic Polymorphism, Alcoholic Beverage Type and Ethanol Metabolism [PDF]

open access: yes, 2018
Objective To explore the effects of ADH1B and ALDH2 gene polymorphism and type of alcoholic beverage on ethanol metabolism, to provide data support for cases involving the interpretation of ethanol metabolism or back calculation of blood ethanol ...
YE Yi, CHEN Fan, LU Xiang, et al
core   +1 more source

Importance of connectivity for carnivore richness and occupancy in fragmented biodiversity hotspots

open access: yesConservation Biology, Volume 39, Issue 6, December 2025.
Abstract Structural connectivity affects wildlife movement between habitat patches, contributing to the persistence of wildlife populations and their resilience to human‐induced and environmental changes. However, its importance to wildlife population persistence remains unclear, particularly in fragmented landscapes, where there are additional co ...
Cindy M. Hurtado   +12 more
wiley   +1 more source

白介素8-251 位点基因多态性与我国高低发区胃癌关系 [PDF]

open access: yes, 2005
【目的】研究白介素(interleukin, IL)-8 基因- 251A/T 位点多态性在中国高、低发区普通人群和胃癌 (gastric cancer , GC)患者中的分布, 并探讨其基因多态性与我国胃癌的关系。【方法】用聚合酶链反应- 反向杂 交法(polymerase chain reaction and reverse dot blot, PCR-RDB)检测我国胃癌低发区( 广东省) 104 例健康人和 104 例胃癌患者和胃癌高发区( 陕西省) 102 例健康人和102 ...
周韶璋   +6 more
core  

Coexistence and habitat restoration planning for the reintroduction of Spix's macaw

open access: yesConservation Biology, Volume 39, Issue 6, December 2025.
Abstract Spix's macaw (Cyanopsitta spixii) is one of the world's most endangered species. Native to the Caatinga of northeastern Brazil—a region marked by significant socioeconomic vulnerability—the species was considered extinct in the wild in 2000. A reintroduction project, however, returned it to its natural habitat in 2022. The long‐term success of
Ugo Eichler Vercillo   +3 more
wiley   +1 more source

中国汉族群体 D4S111 位点的遗传多态性研究

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 1998
目的: 研究中国汉族群体中 α -艾杜糖苷酶基因 D4S111 位点的遗传多态性 。方法: 采用扩增片段长度多态性 (Amp-FLP)分析技术,检测了广州地区汉族无血缘关系健康个体 97 名。结果: D4S111 位点, 在 97 名无关个体中发现 5 个等 位基因和 9 种基因型,等位基因片段长度为 830~ 510 bp, 基因频率为 0. 0 052~ 0. 3 608, PIC 为 0. 5 966,杂合性为 0.
光 炜 郭奕斌 林群娣 杜传书
doaj  

MDR1基因多态性与肝癌易感性的关系 [PDF]

open access: yes, 2009
目的:探讨MDR1基因位点单核苷酸多态性与肝癌易感性的关系。方法:采用病例对照研究,应用聚合酶链反应限制性片段长度多态性(PCR-RFLP)基因型分析技术测定原发性肝癌组及正常健康对照组各100例MDR1基因G2677T/A位点。以χ2检验比较MDR1多态基因型及相关危险在病例与对照之间分布的差异,采用非条件Logistic回归分析多态基因型与肝癌发生危险度的关系。结果:肝癌组MDR1基因2677A携带型低于健康对照组 ...
冯水土, 张永兴, 杨芳, 陈毅德
core  

Accounting for human–nature linkages in area‐based conservation monitoring through social–ecological indicator bundles

open access: yesConservation Biology, Volume 39, Issue 6, December 2025.
Abstract As the coverage of area‐based conservation increases across the globe, it is critical to improve understanding of the social and ecological outcomes of such measures and the pathways to their outcomes. A social–ecological systems approach to monitoring and evaluation is increasingly advocated; yet, applications remain scarce.
Natalie C. Ban   +21 more
wiley   +1 more source

The effect of pentosan polysulfate on diabetic nephropathy renal tubular epithelial cells injury through regulating p38 MAPK signaling pathway [PDF]

open access: yes, 2016
目的:观察戊糖多硫酸钠是否通过调控P38MAPK干预糖尿病肾病肾小管上皮细胞的损伤。方法:利用不同浓度(10mmol/L~50mmol/L)葡萄糖刺激肾小管上皮细胞(HK-2)48h,应用CCK-8比色法检测肾小管上皮细胞增殖的改变。利用不同时间段(0h~48h)葡萄糖刺激细胞,用Westernblot法检测P38MAPK蛋白的表达水平。分为正常对照组(control组)、高糖组(HG组,葡萄糖30mmol/L)、戊糖多硫酸钠(PPS)组(PPS200µg/mL)、高糖+戊糖多硫酸钠组(HG+
张天英
core  

[Research advances in genetic polymorphisms in Kawasaki disease]. [PDF]

open access: yesZhongguo Dang Dai Er Ke Za Zhi, 2023
Dong MX, Wang XX, Jiao FY, Zhang WH.
europepmc   +1 more source

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