Results 51 to 60 of about 22,208 (188)
Correlation of Genetic Polymorphism, Alcoholic Beverage Type and Ethanol Metabolism [PDF]
, 2018 Objective To explore the effects of ADH1B and ALDH2 gene polymorphism and type of alcoholic beverage on ethanol metabolism, to provide data support for cases involving the interpretation of ethanol metabolism or back calculation of blood ethanol ...
YE Yi, CHEN Fan, LU Xiang, et al
core +1 more source
Synthesizing Empirical Research on Learner Metacognition in Second Language Writing
International Journal of Applied Linguistics, EarlyView.ABSTRACT Despite considerable research interest in learner metacognition in second language (L2) writing, there is not yet a review that synthesizes the existing empirical findings and discusses their implications. To fill the void, this systematic review synthesized 39 empirical studies on learner metacognition in L2 writing and examined their salient
Chen Li, Icy Lee, Zhicheng Mao
wiley +1 more source
基于多色探针熔解曲线分析技术的华法林个体化用药相关基因多态性快速检测方法 [PDF]
, 2019 华法林是一种广泛使用的抗凝剂，其治疗窗口较窄，患者间达到抗凝所需剂量的变异性大。已有研究表明CYP2C9*3 (rs1057910)、CYP2C9 IVS3-65G>C (rs9332127)、VKORC1 c.-1639G>A (rs9923231)和CYP4F2*3 (rs2108622)的单核苷酸多态性（SNP）是影响中国人群华法林敏感性的主要遗传因素。该研究利用多色探针熔解曲线（MMCA）技术，建立可同时检测4个华法林敏感性基因多态性的单管PCR反应体系，可在2.5 h内完成检测，能检测低至50
夏众敏 +3 more
core +3 more sources
Zhongguo shiyan zhenduanxue, 2013 目的探讨原发性宫颈癌人群中NF-κB信号传导通路相关基因多态性与宫颈癌发生发展的关系。方法以广西壮族自治区肿瘤医院2008年9月-2009年9月收治的宫颈癌患者与健康体检者各100名为研究对象,利用限制性片段长度多态性检测法检测研究对象该通路相关基因的基因多态性,进行对比分析。结果 NF-κB信号传导通路相关基因多态性型别在两组研究对象中出现的频率无显著性差别,P>0.05;变异等位基因出现频率与以往结果相一致。结论 NF-κB信号传导通路相关基因多态性与宫颈癌的发生发展无明确的相关关系。
宋红林, 张洁清
doaj
白介素8-251 位点基因多态性与我国高低发区胃癌关系 [PDF]
, 2005 【目的】研究白介素(interleukin, IL)-8 基因- 251A/T 位点多态性在中国高、低发区普通人群和胃癌 (gastric cancer , GC)患者中的分布, 并探讨其基因多态性与我国胃癌的关系。【方法】用聚合酶链反应- 反向杂 交法(polymerase chain reaction and reverse dot blot, PCR-RDB)检测我国胃癌低发区( 广东省) 104 例健康人和 104 例胃癌患者和胃癌高发区( 陕西省) 102 例健康人和102 ...
周韶璋 +6 more
core
Genomic responses to increased temperature and pollinator selection in Brassica rapa L.
New Phytologist, EarlyView.Summary Rapid environmental change reshapes both abiotic stress and biotic interactions, yet it remains unclear how these combined forces structure plants' genomic adaptation. In particular, the joint influence of temperature and pollinator identity, two ecological axes undergoing simultaneous global shifts, has rarely been quantified at genomic ...
Yanqian Ding, Florian P. Schiestl
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2012 目的探讨原发性肝细胞癌人群中谷胱甘肽巯基转移酶基因多态性与肝癌发生、发展的关系。方法我院2008年10月-2010年4月收治的原发性肝癌患者与健康体检者各150名,提取血样,利用多重PCR和限制性片段长度多态性检测法分别检测肝癌人群与体检健康者的谷胱甘肽巯基转移酶基因多态性,并进行对比分析。结果该肝癌人群中:谷胱甘肽巯基转移酶基因多态性型别在病例和对照组研究对象中出现的频率无显著性差别,P>0.05;GSTM1-null、GSTT1-null、GST01-Ala140Asp、GSTP1 ...
唐耘天 +5 more
doaj
Association between Methylenetetrahydrofolate Reductase Gene Single Nucleotide Polymorphisms and Lower Extremity Atherosclerotic Disease [PDF]
, 2016 目的:研究汉族人群中亚甲基四氢叶酸还原酶(methylene-tetrahydrofolate reductase,MTHFR)基因多态性与下肢动脉粥样硬化(lower extremity atherosclerotic disease,LEAD)的相关性。方法:收集福建省闽南地区384例(LEAD者224例,健康者160例)的临床资料及外周血;LEAD检查采用踝肱指数(ABI)、趾肱指数(TBI)、多普勒彩超和其他影像学检查等手段;选取MTHFR基因rs1801133、rs1801131 ...
李红娜 +5 more
core
Coalition Opportunity Structures and Advocacy Coordination in Consensus and Majoritarian Democracies
Policy Studies Journal, EarlyView.ABSTRACT Research on advocacy coalitions suggests that belief homophily—the tendency of actors to coordinate based on shared policy beliefs—drives coalition formation. However, coalition opportunity structures, which are shaped by institutional contexts, may influence the extent to which belief homophily matters.
Keiichi Satoh +7 more
wiley +1 more source
TLR-9 rs187084基因多态性与山东汉族人群系统性红斑狼疮的相关性研究
Zhongguo shiyan zhenduanxue, 2009 目的研究山东地区汉族人群TLR-9基因rs187084单核苷酸多态性,探讨其与系统性红斑狼疮易感性之间的关系。方法采用聚合酶链反应和限制性片段长度多态性等方法对92例系统性红斑狼疮患者和88名健康对照TLR-9基因rs187084C/T多态性进行分析,计算基因型和等位基因频率。结果（1）SLE患者TLR-9基因rs187084CC、CT、TT基因型频率分别是0.185、0.413和0.402,与对照组相比没有统计学差异（χ2=2.99,P>0.05）;（2）SLE患者TLR-9基因rs187084C ...
宋卫青 +4 more
doaj