Results 141 to 150 of about 38,507 (214)
Zhongguo shiyan zhenduanxue, 2008 目的探讨FⅫ基因exon146C/T基因多态性与血栓形成的关联性。方法采用PCR-RFLP法鉴定了92例血栓性脑梗塞患者和87例静脉血栓患者及129例健康人的FⅫ基因exon146C/T基因型及C、T等位基因分布频率,采用多元Logistic非条件回归分析方法,进行多因素分析,解析FⅫ基因46C/T多态性与血栓性脑梗塞、静脉血栓形成的关联性。结果血栓性脑梗塞组和静脉血栓组的C等位基因分布频率均高于对照组,血栓性脑梗塞组的C/C基因型在血栓形成中的危险性是T/T基因型的14.533倍,具有统计学意义 ...
张玲 +5 more
doaj
血管紧张素转换酶、内皮型一氧化氮合酶和载脂蛋白E基因多态性与冠心病的相关性
Zhongshan Daxue xuebao. Yixue kexue ban, 2006 [目的]研究血管紧张素转换酶（ACE）基因插入/缺失多态性、内皮型一氧化氮合酶（eNOS）基因G894T多态性和载脂蛋白E（ApoE）基因多态性与冠状动脉粥样硬化性心脏病（冠心病）的关系.[方法]应用基因芯片技术分析133例冠心病患者和122例对照者ACE、eNOS和ApoE基因多态性,对比两组基因型及等位基因频率.[结果]冠心病组ACE DD基因型频率比对照组显著升高,28.6% vs 13.1%,P＜0.01,ACE基因多态性与冠心病危险性相关.两组eNOS和ApoE基因型频率差异无统计学意义（P ...
梁茜 +4 more
doaj
Zhongguo shiyan zhenduanxue, 2008 目的探讨缺氧诱导因子（HIF-1α）基因治疗家兔肢体缺血模型的疗效。方法在家兔缺血模型的肢体内注射携带/HIF-1α基因的重组腺病毒AdHIF-1α,检测HIF-1α基因在缺血肌组织中表达情况,并观察其生物学特点。实验以携带GFP基因的重组腺病毒AdGFP为对照。结果免疫组化染色均检测到HIF-1α的表达。转AdHIF-1α基因治疗组毛细血管计数及小动脉计数均高于AdGFP转导的对照组 ...
孙晓峰 +5 more
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[Diagnostic value of intestinal tissue metagenomic next-generation sequencing in severe diarrhea following haploidentical hematopoietic stem cell transplantation]. [PDF]
Zhonghua Xue Ye Xue Za ZhiLin QX +10 more
europepmc +1 more source
[Application value of metagenomic next-generation sequencing for pathogen detection in childhood agranulocytosis with fever]. [PDF]
Zhongguo Dang Dai Er Ke Za Zhi, 2022 Zhu S +5 more
europepmc +1 more source
[Diagnosis of mucormycosis in three children following hematopoietic stem cell transplantation using metagenomic next-generation sequencing]. [PDF]
Zhongguo Dang Dai Er Ke Za ZhiLi Y +5 more
europepmc +1 more source
Efficient genome editing in medaka (Oryzias latipes) using a codon-optimized SaCas9 system. [PDF]
J Zhejiang Univ Sci BJiang Y +5 more
europepmc +1 more source
Global analysis of DNA methylation changes during experimented lingual carcinogenesis. [PDF]
Hua Xi Kou Qiang Yi Xue Za ZhiLiu H +5 more
europepmc +1 more source