Results 21 to 30 of about 32,642 (169)
为认识我国淡水鱼类烂鳃病的病原以及柱形病在我国的发生情况,实验从发生烂鳃病的病鱼中分离细菌性病原,经过生理生化特性分析以及是否在含托普霉素的Shieh培养基中生长并形成黄色假根状菌落,是否产生降解明胶和硫酸软骨素的酶类等特性的鉴定,并结合16SrDNA序列分析,证实柱状黄杆菌(Flavobacterium columnare)是所分离的烂鳃病的病原。同时,研究也证实20世纪曾经命名为烂鳃(Gill-rot)病病原的鱼害黏球菌(Myxococcus piscicola Lu,Nie & Ko,1975 ...
姚卫建 +7 more
core
Plant phenomics is under rapid development in recent years, a research field that is progressing towards integration, scalability, multi-perceptivity and high-throughput analysis.
Guohui, Ding +6 more
core +1 more source
ABSTRACT Although the use of AI technologies (e.g., chatbots and automated writing evaluations (AWE)) has gained considerable attention in language learning fields in recent years, how AI technologies have been designed and implemented in language learning education, as well as their effectiveness, is understudied.
Shen Qiao +2 more
wiley +1 more source
膀胱移行细胞癌组织基因的P14ARF、DAPK、RARβ甲基化变异分析
目的通过检测新鲜冰冻膀胱癌组织中P14ARF、DAPK、RARβ基因的启动子CpG岛基因的甲基化状态,探讨P14ARF、DAPK、RARβ在膀胱癌发生过程中的作用及诊断意义。方法采用甲基化特异性PCR技术检测48例手术切除的膀胱癌组织和其中13例相应癌旁组织标本、17例非肿瘤患者正常膀胱组织中DAPK、RARβ、P14ARF基因的甲基化情况。结果 48例膀胱癌组织中发现P14ARF基因异常甲基化13例(27.0%),DAPK基因异常甲基化13例(27.0%);RARβ基因异常甲基化44例(91.6 ...
王凯臣 +5 more
doaj
Exomic somatic variation of esophageal squamous cell carcinoma [PDF]
目的:食管鳞状细胞癌(esophagealsquamouscellcarcinoma,ESCC)是全球常见的致死性恶性肿瘤。为进一步探讨其分子机制,我们利用全基因组外显子测序技术寻找食管鳞癌中多发的突变,包括点突变、结构变异等,并且进一步鉴定食管鳞癌中多发的单核苷酸变异(Singlenucleotidevariation,SNV)。在体细胞水平探讨食管鳞癌发生发展的分子机制。 方法:1.通过外显子测序生成并收集数据库ESCC测序数据。2.128对食管鳞癌外显子测序数据采用新一代基因序列比对方法 ...
李慧莉
core
ABSTRACT Many existing rubrics for L2 argumentative writing prioritize form‐based linguistic accuracy and complexity while insufficiently addressing substantive argumentative rigor and effectiveness. This limitation is further complicated by cross‐cultural variation in rhetorical conventions and educational practices, which challenge the direct ...
Zihan Xu, Peiyun Liu
wiley +1 more source
Research on several important genes and genetically engineered vaccines of Koi herpesvirus [PDF]
高密度集约化养殖成为当下主要的水产养殖方式,带来较大收益的同时也导致鱼类病毒的更大范围的流行。传统使用化学消毒剂以及抗生素的鱼病防治策略引发了一系列严峻问题。鱼用疫苗作为一种经济高效的水产养殖防治措施渐渐引起大家的关注与重视。鲤鱼是我国的主要食用鱼种,在我国得到大范围的养殖,创造了巨大的经济效益。锦鲤是一种观赏用的花色鲤鱼,体色漂亮,色彩鲜艳,是淡水养殖观赏鱼中的精品,被称为水中宝石。1998年由以色列开始暴发的锦鲤疱疹病毒病给食用鲤鱼和观赏锦鲤的养殖造成了极大的危害 ...
庞纪明
core
ABSTRACT As the public sector increasingly adopts AI‐powered automated decision systems (ADS), understanding how citizens experience and value ADS use in public decision‐making is both normatively and practically important. Therefore, we examine and compare the effects of seven attributes of public values on citizens' support for ADS adoption in two ...
Guimin Zheng +4 more
wiley +1 more source
细胞毒性T 淋巴细胞相关抗原4 基因型与中国南方人群Graves ’ 病的关系
【目的】探讨细胞毒性T淋巴细胞相关抗原-4(cytotoxic T lymphocyte associated antigen 4)基因第一外显子A/G(49)多态性与中国南方汉族人群Graves′病的关系。【方法】用PCR-RFLP确定CTLA-4基因第1外显子49位点基因型,分析广东地区汉族人Graves′病患者(GD组)120例及123名正常人(对照组)CTLA-4基因多态性。并把GD患者按性别、家族史、TRAb、突眼等分别分两亚组后分析CTLA-4基因第1外显子A49G位点基因型及等位基因的频率。
姚斌 +4 more
doaj
The epigenetic mechanism of imprinted gene IGF2 regulated by MEN1 in hepatocellular carcinogenesis [PDF]
原发性肝癌是肝细胞或肝内胆管上皮细胞发生的恶性肿瘤。死亡率仅次于胃癌和食道癌,其中肝细胞癌(hepatocellularcarcinoma,HCC)占原发性肝癌的90%。我们实验室围绕menin复合物调控的组蛋白甲基化与疾病发生关系开展了较系统深入的研究,证明了menin在肝细胞肝癌、非小细胞型肺癌及恶性黑色素瘤等非内分泌系统肿瘤中的重要生物学功能,阐明了menin调控组蛋白甲基化修饰的规律及机制。胰岛素样生长因子——2(insulinlikegrowthfactor2,IGF2 ...
丁丽红
core

