Results 21 to 30 of about 984,022 (166)
AI foundation models in plant biology
Foundation models decode genomes, engineer proteins, phenotype crops, and drive AI agents across plant biology. This figure was created in BioRender (BioRender.com/xcmmkel). Summary Rapid technological progress has enabled plant biologists to accumulate unprecedented volumes of multi‐scale, multi‐modal data, yet this abundance of data has intensified ...
Haopeng Yu
wiley +1 more source
ABSTRACT As the public sector increasingly adopts AI‐powered automated decision systems (ADS), understanding how citizens experience and value ADS use in public decision‐making is both normatively and practically important. Therefore, we examine and compare the effects of seven attributes of public values on citizens' support for ADS adoption in two ...
Guimin Zheng +4 more
wiley +1 more source
有性生殖的关键过程是通过减数分裂产生生殖细胞,而减数分裂的一个重要环节是进行基于DNA双链断裂的同源染色体重组。在同源染色体重组过程中,SPO11蛋白催化产生DNA双链断裂,从而起始同源染色体的重组。因此,研究SPO11基因缺失在减数分裂过程中所引起的基因表达变化有助于在转录组水平上了解该基因的作用。本研究通过对嗜热四膜虫(Tetrahymena thermophila)野生型和SP011敲除细胞株在接合生殖时期2 h、3 h、4 h、5 h四个时间点的转录组进行高通量测序 ...
闫冠雄 +5 more
core +1 more source
ABSTRACT Arranging functional units into a specific organization is a practical structural strategy for achieving fabulous performance, known as the functional unit and organization (FUO) paradigm. This paradigm offers a concise shortcut to establishing structure–performance relationships.
Zhongtao Lu +5 more
wiley +1 more source
单细胞原核生物是原始的细胞生命形式,确定细菌必需基因和最小基因组对理解生命的本质、细胞生命的起源和进化有非常重要的意义。文中简要介绍近年来有关细菌的必需基因、最小基因组和合成细胞的研究方法、理论和进展 ...
邱东茹
core +1 more source
ABSTRACT Osteoarthritis (OA) therapy remains constrained by the coexistence of irreversible cartilage loss and a persistently hostile joint microenvironment characterized by oxidative stress, synovial inflammation, and impaired tissue‐regenerative signaling.
Xinyu Wu +11 more
wiley +1 more source
副地衣芽孢杆菌(Bacillus paralicheniformis)FA6是一株从草鱼肠道内分离出来的细菌,其具有淀粉酶和纤维素酶等多种碳水化合物酶活性。为深入研究副地衣芽孢杆菌FA6可能的益生机制,研究通过三代测序技术测定了副地衣芽孢杆菌FA6的全基因组序列,运用生物信息学方法进行基因组组装、基因预测和功能注释。同时通过比较基因组学方法,比较分析了副地衣芽孢杆菌FA6与4株基因组序列已经发表的芽孢杆菌基因组结构和功能的差异。结果发现副地衣芽孢杆菌FA6全基因组由1条环状染色体组成 ...
吴山功, 赵帝, 丰文雯
core +1 more source
目的探讨大肠肿瘤p53和ki-ras基因协同突变的临床意义。方法采用免疫组化和PCR-SSCP方法,检测58例大肠肿瘤患者的良性病变、良性病变转为恶变、原发腺癌组织的p53基因、ki-ras基因的表达和突变情况。结果良性病变组与恶变组间的p53基因和Ki-ras基因的表达有显著差异,良性病变组与原发腺癌组的Ki-ras基因表达差异显著;良性病变组的p53基因与Ki-ras基因的表达呈负相关,而恶变组和原发腺癌组呈正相关。p53基因和ki-ras基因两种基因突变率无显著差异,而协同突变与淋巴结转移密切相关,
侯睿哲 +3 more
doaj
佳木斯地区原发性高血压合并高尿酸血症与MTHFR基因多态性的相关性研究
目的探讨MTHFR基因的基因多态性与原发性高血压合并高尿酸血症易感性之间的关系。方法选取符合要求的392例患者作为研究对象,其中对照组(n=102)、原发性高血压组(n=109)、高尿酸血症组(n=86)和原发性高血压合并高尿酸血症(n=95)。用DNA提取试剂盒提取入组人群的DNA,再通过聚合酶链反应-高分辨率溶解曲线(PCR-HRM)的方法进行基因分型,记录结果并分析原发性高血压合并高尿酸血症与MTHFR C677T基因多态性的相关性。结果在各实验组中,MHTFR C677T基因的CT ...
隋小芳 +8 more
doaj
ABSTRACT This paper describes and analyzes recharge practices in Bács‐Kiskun County, Hungary, within what can be categorized as the farmer domain. Such locally embedded aquifer recharge practices remain underexplored in Hungary. Current research and funding largely focus on large‐scale Managed Aquifer Recharge (MAR) interventions emphasizing intended ...
Helen Sundberg, Michael Gilek
wiley +1 more source

