Results 21 to 30 of about 32,478 (167)
Conservation Biology, EarlyView.Abstract Human development is a driver of global change and a major threat to biodiversity. Protected areas maintain and support biodiversity, but outside stressors, such as climate change and land use change, can negatively influence natural resources within protected areas.
Leah J. Rudge +2 more
wiley +1 more source
DNA Methylation and Non-small Cell Lung Cancer [PDF]
, 2010 Genomic DNA methylation is a major form of epigenetic modification. Hypermethylation could affect the binding of transcription factors to DNA and change the structure of chromatin resulting in silence of tumor suppressor genes, which plays an important ...
Longbang CHEN, Youwei ZHANG
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Conservation Biology, EarlyView.Abstract Achieving global conservation policy goals requires the ability to set and measure progress toward science‐based targets for biodiversity. The species threat abatement and restoration (STAR) metric was developed to enable actors to set science‐based targets for species.
Louise Mair +17 more
wiley +1 more source
Immediate Versus Delayed Topotecan after First-line Therapy in Small Cell Lung Cancer [PDF]
, 2010 Background and objective How to prolong progression free survival (PFS) and overall survival (OS) of patients with small cell lung cancer (SCLC) has been one of the hottest issues. We retrospectively reviewed our data to compare the survival of immediate
Cong XUE +7 more
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Defining and identifying relevant stakeholders to advance effective conservation
Conservation Biology, EarlyView.The challenge of defining stakeholders in environmental science and an approach for refining existing definitions. Abstract Stakeholder is a contested term that has spawned a multitude of ad hoc definitions. The ambiguity of these definitions has oftentimes impeded transdisciplinary research in environmental governance and conservation science because ...
Milan Büscher +5 more
wiley +1 more source
Advancing conservation breeding programs for marine invertebrates
Conservation Biology, EarlyView.Abstract In the face of ecosystem change and biodiversity loss caused by climate change and other stressors, conservation breeding, or captive breeding, with the aim of reintroduction for wild population recovery, is an emerging tool for preventing species’ extinction and rehabilitating ecosystems.
Elora H. López‐Nandam +3 more
wiley +1 more source
Potential Diagnosis and Prognosis Value of Plasma MicroRNA-19a in Esophageal Cancer [PDF]
, 2015 背景：食管癌是发生于食管上皮组织的恶性肿瘤，具有高死亡率、高复发率和高转移率的特点。然而目前针对食管癌敏感的肿瘤标志物不多，且诊断效率较低，远远不能满足临床需求。MicroRNA是一类非编码RNA，可以稳定存在于人体血浆中并且易于检测。据报道，microRNA在诸多疾病状态下会出现表达异常，如食管癌、结直肠癌、肝癌等，这一发现极大地增加了血浆microRNA作为食管癌标志物的可能。在前期实验中，我们观察到microRNA-19a（miR-19a）在食管癌血浆标本中高表达，本文将重点探讨miR ...
白永颖
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Conservation Biology, EarlyView.Abstract Although significant biodiversity has been safeguarded by protected areas (PAs), biodiversity trends continue downward. Within the frameworks of the EU Biodiversity Strategy for 2030 and the new EU Restoration Regulation (2024), conserving critical biodiversity areas is essential.
George Kefalas +14 more
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2001 【目的】探讨细胞周期调节因子在鼻咽癌复发中的作用。【方法】采用LsAB 法同时检测69 例患者原发和复发 鼻咽癌组织中p53、MDM2 、p21ras和p21WAF1蛋白的表达。【结果】复发癌与原发癌相比:阳性表达率方面, p53 蛋白(78 %和 80 %)或MDM2 蛋白(84%和83%)很相近, p21ras蛋白(73 %和93 %)或p21WAF1蛋白(52 %和84 %)明显下降;高表达率方面, p53 蛋白(42%和51 %)很相近, MDM2 蛋白(57 %和32 %)明显升高 ...
李锦添 +4 more
doaj
Evaluating synthetic substitutes to reduce illegal harvesting and support species recovery
Conservation Biology, EarlyView.Abstract Providing synthetic substitutes is a widely promoted strategy to shift consumer demand away from wildlife products derived from threatened species. Yet, there is little evidence on whether product substitution prevents illegal or unsustainable harvesting and contributes to the recovery of threatened populations.
Aditya Shekhar Malgaonkar +17 more
wiley +1 more source