Results 41 to 50 of about 32,478 (167)

Insights for conservation from the Ecological Knowledge Games project

open access: yesConservation Biology, EarlyView.
Abstract Environmental conservation research requires robust methods for collecting large‐scale behavioral data and engaging diverse stakeholders in decision‐making processes. We (Y.P., A.B.D., and N.B.) created EcoKnowGames (Ecological Knowledge Games), a transdisciplinary project that develops knowledge games for conservation science and data ...
Yuan Pan   +4 more
wiley   +1 more source

The mechanism and function of extracellular matrix protein Mindin in the colon cancer progression [PDF]

open access: yes, 2015
在世界范围内,结直肠癌是临床上常见的恶性肿瘤之一。结肠癌的发病机制也在不断细致、深入的研究。然而结肠癌这种实体肿瘤不像单纯的肠癌细胞系。相反,它是由多种类型的细胞和细胞外基质组成的功能失调的器官。细胞外基质是肿瘤微环境的重要组成部分,包含各种各样的细胞因子和代谢产物,具有向细胞传导各种环境信号的作用。这些信号对于细胞生命过程的方方面面都必不可少,包括增殖、分化和死亡等。然而,细胞外基质蛋白在结肠癌发生发展的演变过程中的作用尚未完全明确。 分泌型的细胞外基质蛋白Mindin作为Mindin-F ...
肖传兴
core  

Synthesizing Empirical Research on Learner Metacognition in Second Language Writing

open access: yesInternational Journal of Applied Linguistics, EarlyView.
ABSTRACT Despite considerable research interest in learner metacognition in second language (L2) writing, there is not yet a review that synthesizes the existing empirical findings and discusses their implications. To fill the void, this systematic review synthesized 39 empirical studies on learner metacognition in L2 writing and examined their salient
Chen Li, Icy Lee, Zhicheng Mao
wiley   +1 more source

复合绝缘子表面异常发热现象分析及其抑制措施

open access: yesDianci bileiqi, 2020
近年来高压输电线路复合绝缘子异常发热频繁发生,对电网安全运行产生严重影响;但目前对其深入研究不够,通常把复合绝缘子异常发热同内绝缘缺陷简单对应,从而盲目采取更换等处理措施,造成人力物力极大浪费。为此,对某500 kV输电线路复合绝缘子大面积异常发热现象进行分析,通过试验分析发现其属于护套表面异常发热,与内绝缘缺陷无直接关联。试验结果表明:随着端部场强增大,异常发热温升增大,表层污秽去除后,异常发热现象消失。提出调整均压环配置来抑制复合绝缘子表层发热,通过带电作业方式实施后 ...
黄振   +6 more
doaj  

Expression and Clinical Relevance of uPA and ET-1 in Non-small Cell Lung Cancer [PDF]

open access: yes, 2011
Background and objective uPA and ET-1 proteins have been reported to be up-regulated in some of human cancers. The aim of this study is to investigate the alteration and clinical relevance of uPA and ET-1 protein levels in non-small cell lung cancer ...
Boshi WANG   +7 more
core  

Assessing Argument Quality in L2 Argumentative Writing: Integrating Argument Elements and Intellectual Standards

open access: yesInternational Journal of Applied Linguistics, EarlyView.
ABSTRACT Many existing rubrics for L2 argumentative writing prioritize form‐based linguistic accuracy and complexity while insufficiently addressing substantive argumentative rigor and effectiveness. This limitation is further complicated by cross‐cultural variation in rhetorical conventions and educational practices, which challenge the direct ...
Zihan Xu, Peiyun Liu
wiley   +1 more source

PCNA和DNA含量估测腮腺混合瘤增殖活性

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 1997
摘 要 为了评价增殖细胞核抗原( PCN A)表达和DN A含量在研究腮腺混合瘤细胞增殖活性中的价值, 对60 例良性无复发、复发和恶性腮腺混合瘤用PCN A免疫组化染色技术和流式细胞测量术作PCNA测定和 DN A含量测量。结果显示PCNA表达在各组间和高S期细胞比率( S PF)在无复发和复发组间有显著差异;恶性 混合瘤组与良性无复发组或复发组间有显著差异; PCN A表达与高SPF呈显著性正相关关系。提示PCN A表达 和DN A含量均能反映良恶性混合瘤细胞增殖活性 ...
陈伟良 孔庆瑜 李海刚 陈光晔 任材年
doaj  

3D打印引导下的放疗后复发宫颈癌组织间插植1例报道

open access: yesZhongguo shiyan zhenduanxue, 2021
宫颈癌是世界上最常见的恶性肿瘤之一,长期以来困扰女性的生命健康,全球每年超过50万女性被诊断为宫颈癌,导致每年30万人死亡[1]。25%-61%的患者在初次治疗后复发,复发时间通常在初治后的两到三年内[2-3]。宫颈癌复发患者预后差,是导致宫颈癌患者死亡的主要原因。复发后的治疗需根据病变部位及初次治疗方式选择,增加了治疗的难度和复杂性。
孙婧, 巴秀敏, 李云峰, 王铁君
doaj  

一种基于经验分布的大地震复发概率计算方法

open access: yesDizhen xuebao, 2018
以历史重演原则和构造类比原则为基础,提出了一种基于经验分布的大地震复发概率计算方法,该方法不作任何复发概率分布的强假定,直接通过对大量地震序列数据的蒙特卡罗随机抽样来模拟未来大地震的复发规律,进而统计得到未来一段时间内的大地震发生概率,并以鲜水河断裂带炉霍段和道孚段为实例,利用本文给出的复发概率计算方法得出炉霍段和道孚段未来50年大地震发生概率分别为0.15和0.31。
Xing Guo   +3 more
doaj   +1 more source

Mechanisms of activity hepatic stellate cells induced myeloid-derived suppressor cells accumulation and migration [PDF]

open access: yes, 2015
原发性肝癌(hepatocellularcarcinoma,HCC)是全球第五大常见的恶性肿瘤,在肿瘤致死的病因中排名第三位。在全球,每年有超过50万人死于肝癌,且一半以上在中国。随着科学研究的发展,科研人员发现肝癌的发生发展不仅仅是病毒感染、环境因素、基因突变这些因素,肿瘤微环境对肿瘤的发生、发展、复发转移有着重要作用。肝脏是一个具有“免疫特赦”的脏器,肝癌微环境中的非实质细胞及其细胞因子是肝癌的免疫逃逸,复发转移的重要因素。 肝星状细胞(hepaticstellatecell,HSCs ...
许雅苹
core  

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