Results 31 to 40 of about 5,734 (165)

In vitro antimicrobial activity of a gel containing antimicrobial peptide AMP2041, chlorhexidine digluconate and Tris‐EDTA on clinical isolates of Pseudomonas aeruginosa from canine otitis

open access: yesVeterinary Dermatology, Volume 27, Issue 5, Page 391-e98, October 2016., 2016
Background– Pseudomonas aeruginosa (PA) may cause suppurative otitis externa with severe inflammation and ulceration in dogs. Multidrug resistance is commonly reported for this organism, creating a difficult therapeutic challenge. Objective– The aim of this study was to evaluate the in vitro antimicrobial activity of a gel containing 0.5 µg/mL of ...
Giovanni Ghibaudo   +6 more
wiley   +1 more source

Bacteriophage and Fusidic Acid Have Synergistic Effect Against Meticillin‐Resistant Staphylococcus pseudintermedius in Ex Vivo Canine Dermis Model

open access: yesVeterinary Dermatology, EarlyView.
Background: Antimicrobial stewardship has become vital given the progressive emergence of multidrug‐resistant bacteria, and novel approaches to the treatment of bacterial infections are needed. Recently, reported synergistic effects of antibacterial drugs and bacteriophage therapy have revealed promising applications for the management of meticillin ...
Sarah Ehling   +9 more
wiley   +1 more source

Serotype distribution and antimicrobial resistance characteristics of Salmonella in chicken meat collected from wholesale markets in Beijing City [PDF]

open access: yes
ObjectiveTo investigate the serotype distribution and antimicrobial resistance characteristics of Salmonella isolated from retail chicken in Beijing City.MethodsA total of 135 Salmonella strains were isolated from retail chicken meat collected from three
BAI Yao   +9 more
core   +1 more source

Distribution of blood culture pathogens and clinical characteristics in children with acute leukemia complicated with septic shock [PDF]

open access: yes, 2022
Objective To explore the distribution of blood culture pathogens and clinical characteristics in children with acute leukemia complicated with septic shock.
Liu Tinghua, Lei Jiaying, Mai Yougang
core   +1 more source

Multi‐Scale Rational Design and Synergistic Strategies of Nanozymes for Targeting Drug‐Resistant Pathogens

open access: yesRare Metals, Volume 45, Issue 1, January 2026.
ABSTRACT The escalating issue of drug‐resistant pathogens, largely driven by the overuse of conventional antibiotics, has become a significant global health threat. Developing alternative therapeutic strategies and fabricating natural biological enzyme materials that mimic the high efficiency, selectivity, and mild‐operating conditions of natural ...
Shuai He   +11 more
wiley   +1 more source

襄阳市第一人民医院儿科PICU四年病原菌分布及耐药性变迁

open access: yesZhongguo shiyan zhenduanxue, 2021
儿科重症监护病房(PICU),在危重病救治中发挥着重要作用[1],是降低患儿病死率的生命绿洲。PICU患者由于年龄层次差别大、病情重,常接受侵袭性的操作和治疗,因此造成的医源性感染较普通病房和门诊要多[2-3],或患儿低龄,医师在患者的用药种类和剂量上受到很大的限制,常选择经验性用药,造成常用药的耐药现象严重及发生多重耐药。本文有针对性的就襄阳市第一人民医院儿科PICU病原菌的分布及常用药的耐药情况做一分析,以区别其他地区儿科PICU病原菌的分布和耐药,报道如下。
任瑞平, 熊永芳
doaj  

Biochemical characteristics and function studies of Esx-1 secretion-associated protein EspL and EspG1 [PDF]

open access: yes, 2016
由巨噬细胞等人体免疫细胞聚集形成的肉芽肿是结核病的形成标志,肉芽肿的形成在结核分枝杆菌的致病过程中扮演着重要角色,它使被感染的宿主与结核分枝杆菌融合在一起。结核分枝杆菌通过特异性的蛋白分泌系统Esx-1分泌系统将具有毒性作用的毒力因子通过高疏水性的细胞膜分泌到胞外。这些毒力因子与宿主中肉芽肿的形成以及结核分枝杆菌毒性作用有关。EspL是结核分枝杆菌Esx-1分泌系统中的一个重要的蛋白,已有研究表明EspL可能通过影响另外两个毒力因子EspE和ESAT-6的分泌而调控肉芽肿的形成 ...
田双良
core  

To Ban or Not to Ban: The UK's Hamlet Moment With Farm Antibiotics

open access: yesPolitics &Policy, Volume 53, Issue 6, December 2025.
ABSTRACT This article applies the Multiple Streams Framework (MSF) to examine post‐Brexit antimicrobial resistance (AMR) governance in UK agriculture, focusing on the contested regulation of prophylactic antibiotic use in farm animals. The study reveals how Brexit created a structural policy window, yet political and ideological dynamics rendered it ...
George Asiamah
wiley   +1 more source

Effect of different antibiotics combined with tigecycline in patients with multidrug-resistant Acinetobacter baumannii-related ventilator-associated pneumonia: A comparative study [PDF]

open access: yes
Objective To investigate the effect of different antibacterial agents combined with tigecycline in patients with multidrug-resistant Acinetobacter baumannii (MDRAB)-related ventilator-associated pneumonia (VAP), and to provide options for better ...
SHI Xinyan, SHANG Ning, WANG Hong, YANG Tingting, ZHAO Chunling, QI Weiwei, LIU Wei
core   +1 more source

Salmonella contamination and molecular typing in Huzhou from 2015 to 2021 [PDF]

open access: yes, 2023
ObjectiveTo understand the pollution status of foodborne pathogens in Huzhou, so as to provide basis for the prevention and control of foodborne diseases.MethodsAccording to GB 4789.4—2016, 1 463 samples in 5 food categories were collected from Huzhou ...
CHEN Liping   +3 more
core   +1 more source

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