Results 21 to 30 of about 13,517 (162)
Biotechnology and Applied Biochemistry, Volume 72, Issue 5, Page 1385-1394, October 2025.ABSTRACT Senkyunolide I (Sen I) has a protective effect on the blood–brain barrier (BBB) in rats with sepsis‐associated encephalopathy (SAE). This study investigated whether Sen I regulates Nrf2 to ameliorate sepsis‐induced brain dysfunction (SIBD). Sixty rats were randomly assigned into Sham group, SAE group (Model group), SAE + Sen I group (72 mg/kg,
Haohao Cao, Tao Liu, Meixia Xu
wiley +1 more source
Wildlife Letters, Volume 3, Issue 3, Page 99-108, September 2025.Climate change is leading to sympatric populations of northern (Glaucomys sabrinus) and southern (Glaucomys volans) flying squirrels; however, we do not know how vital rates like survival are changing following this novel secondary contact. Using mark‐recapture data from sympatric populations, we found nearly identical annual survival rates (0.20 and 0.
Spencer Kielar +4 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2010 目的通过对电针治疗后大鼠局灶性脑缺血模型（MCAO）酪氨酸羟化酶（tyrosine hydroxylase,TH）表达改变的观察,探讨电针对脑可塑性的影响。方法将大鼠随机分为对照组（正常大鼠）、实验组（局灶性脑缺血的大鼠）、治疗组（局灶性脑缺血的大鼠+针刺）,采用荧光定量RT-PCR技术观察各组大鼠TH的动态变化。结果治疗组大鼠TH活性比实验组有显著提高呈阳性表达 ...
田明秀, 陈加俊, 赵静, 黄艳苹
doaj
Tributyltin and bisphenol A induce polycystic ovarian syndrome and its mechanisms involved [PDF]
, 2015 多囊卵巢综合征（polycysticovariansyndrome,PCOS）是以稀发排卵或无排卵、高雄激素或胰岛素抵抗、多囊卵巢为特征的内分泌紊乱的症候群，复杂且具有异质性，是婚育年龄妇女中最常见的内分泌紊乱疾病。PCOS的病因较为复杂，已有研究证明类雌激素化合物双酚A暴露（bisphenolA,BPA）与PCOS的发病有关，说明环境中的内分泌干扰物与PCOS发病存在一定的联系。 本研究以大鼠为实验动物模型，以三丁基锡（tributyltin,TBT）作为类雄激素化合物的典型代表，探究TBT（10ng/
杨志兵
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Environmental DNA, Volume 7, Issue 4, July–August 2025.This study evaluates the effectiveness of three environmental DNA sampling approaches–water eDNA, air eDNA, and leech‐derived iDNA–for surveying vertebrate diversity in the Gaoligong Mountains of southwest China. Using five metabarcoding primer sets, we detected 235 vertebrate species.
Yunyu Wang +6 more
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2006 【目的】探讨自发高血压大鼠心肌肥厚与心室颤动阈值的关系。【方法】20只雄性自发高血压大鼠，随机分成10周龄组（n=10）和18周龄组（n=10）；10只10周龄雄性Wistar大鼠为对照组。分别测定3组大鼠的动脉收缩压、心脏质量指数、心室有效不应期和心室颤动阈值。【结果】①自发高血压大鼠的动脉收缩压和心脏质量指数明显高于Wistar大鼠（P〈0．001），心室颤动阈值明显低于Wistar大鼠（P〈0．001）；②自发高血压大鼠中 ...
黄至斌 +4 more
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Zhongguo shiyan zhenduanxue, 2020 目的探讨移居高原大鼠子代在高原环境中主要脏器发育状况,观察移居高原大鼠子代心脏组织形态学改变。方法将24只(18只雌鼠,6只雄鼠)8周龄wistar大鼠平均分为高原组和平原组,每组12只(9只雌鼠,3只雄鼠)按3:1雌雄比例合笼受孕,所有孕鼠均自然分娩。比较高原组和平原组子代大鼠出生后的第1天、第30天、第60天心、肝、脾、肺、肾、脑的脏器指数,取心脏组织做HE染色检测病理学变化。结果高原组子代大鼠出生第1天体重低于平原组,分别为6.20±0.77g,6.60±0.90g ...
孙薇 +6 more
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The study of brain function changes and related molecular mechanism of rat with chronic obstructive pulmonary disease [PDF]
, 2015 目的 慢性阻塞性肺病（chronicobstructivepulmonarydisease，COPD）以不完全可逆的气流受限和全身系统炎症为特征，可造成脑部供氧不足和神经炎症，导致脑细胞损伤。本研究利用分子生物学等方法探究COPD大鼠脑损伤的分子机制，并为快速诊断出COPD和临床治疗提供依据。 材料和方法 材料：雄性SD大鼠由厦门大学实验动物中心提供，体重230-280g，随机分成4组，健康对照组，吸烟组，脂多糖组，吸烟+脂多糖组，饲养在相同环境下，给予充足的水和食物。 研究方法 ...
严亚
core
An assessment of potential interventions to reduce the totoaba illegal trade market
Conservation Biology, Volume 38, Issue 5, October 2024.Abstract The illegal trade in totoaba (Totoaba macdonaldi) is causing adverse social, ecological, and economic impacts. This illegal activity is accelerating the overexploitation of totoaba and pushing the critically endangered vaquita (Phocoena sinus) closer to extinction.
Rodrigo Oyanedel +3 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2013 目的肝纤维化动物模型大鼠应用雷帕霉素后,检测大鼠肝组织切片中转移生长因子（TGF-β1）表达,探讨雷帕霉素与肝纤维化病理演变的相关性。方法作者将实验大鼠随机分为3组:①正常对照组大鼠（A组）;②肝纤维模型组大鼠（B组）;③肝纤维模型灌注雷帕霉素组（C组）。C组大鼠按2mg/kg体重胃内灌注雷帕霉素,每天1次,持续2周。3组大鼠同期处死,取肝组织进行形态学及组织学研究分析。结果 3组大鼠肝组织切片经HE及免疫组织化等染色后,图片经Image-pro plus 6.0图像分析软件整理。A、B、C ...
钟志宏, 戴东, 陈土明, 吴祖超
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