Results 11 to 20 of about 2,071,692 (156)
阿拉瑞林对SD 大鼠正位与异位子宫内膜雌孕激素受体的影响 [PDF]
Zhongshan Daxue xuebao. Yixue kexue ban, 2002 【目的】观察阿拉瑞林对子宫内膜异位症大鼠异位病灶的抑制作用, 研究其对正位与异位子宫内膜雌激素受体 (ER)、孕激素受体(PR)的影响。【方法】27 只采用外科诱导法建立的子宫内膜异位症大鼠随机分成模型对照组和阿拉瑞林 (alarelin)治疗组, 模型组在同等条件下观察4 周, 阿拉瑞林组以alarelin 30 μg(kg·d)-1皮下注射4 周;治疗结束后, 用链霉素抗 生物素蛋白-过氧化物酶连接法(SP)行正位与异位内膜ER、PR 测定。【结果】阿拉瑞林组大鼠正位和异位子宫内膜生长活动 ...
郑澄宇 +4 more
doaj +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2001 【目的】研究大鼠子宫内膜异位症模型的建立及异位病灶的组织学形态。【方法】采用外科诱导法对80 只大鼠 行建模手术, 在术后的第3 周、第5 周、第7 周和第12 周动态观察病灶的生长情况和大鼠的动情周期变化, 取健侧子宫角中段 的在位内膜、异位内膜行组织学研究。【结果】建模成功率为65 %;生长良好的囊肿囊内壁有内膜上皮细胞生长, 有与正位子 宫内膜接近同步的发情周期改变;病灶随移植时间的推延先逐渐增大之后又有缩小趋势(P
郑澄宇 +5 more
doaj +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2002 【目的】探讨子宫内膜癌雌激素受体(ER)、孕激素受体PR)与临床、病理间的关系。【方法】对83 例子宫内膜癌 患者手术标本常规进行病理检查, 同时采用免疫组化技术检测ER、PR。【结果】子宫内膜癌组织ER、PR 及ER 和PR 同时阳 性率较高, 分别为56.6%、81.9 %、53.0 %。绝经前子宫内膜癌组织ER、PR 阳性率高于绝经后(P
冯华英 +3 more
doaj +1 more source
卵巢子宫内膜异位症微血管密度及血管内皮生长因子表达 [PDF]
Zhongshan Daxue xuebao. Yixue kexue ban, 2004 目的】 探讨子宫内膜异位症血管内皮生长因子(VEGF)的表达,微血管生成及其与临床病理发生的关系? 【方法】 采用S-P免疫组化染色法检测50例卵巢子宫内膜异位症,21例子宫肌瘤在位内膜和10例子宫腺肌症在位内膜中VEGF的表达及微血管密度(MVD)?【结果】 卵巢子宫内膜异位症的VEGF表达阳性率上皮为13.69±4.32?间质为9.24±6.55;MVD(160±53) /mm2,显著高于子宫肌瘤?子宫腺肌症的在位子宫内膜的VEGF阳性表达率与MVD值(P< 0.05),且VEGF与M ...
doaj +1 more source
子宫内膜异位症患者在位和异位内膜组织中 人β防御素-2的表达
Zhongshan Daxue xuebao. Yixue kexue ban, 2009 【目的】 检测人β防御素-2(hBD-2)在正常子宫内膜65380;子宫内膜异位症(内异症)患者的在位和异位内膜组织中的表达,探讨hBD-2在内异症发病中的作用65377;【方法】 选择25例内异症患者的卵巢异位内膜组织(异位内膜组)和相应的在位子宫内膜(在位内膜组),以及25例非子宫内膜异位症的子宫肌瘤患者(对照组)的子宫内膜组织65377;采用实时荧光定量PCR(Real-Time PCR)和原位杂交技术检测各组内膜组织中hBD-2的基因表达,以及hBD ...
doaj +1 more source
, 2023 目的为了探索杂交捕获二代测序技术在子宫内膜癌分子亚型的临床应用。方法收集中山大学附属肿瘤医院经病理确诊的子宫内膜癌112例，均进行基于1 021个基因panel的杂交捕获二代测序检测，分析各分子亚型的分子变异谱及与临床病理特征之间的关系。结果DNA聚合酶ε（POLE）突变型8例（7.1%），错配修复功能缺陷型34例（30.4%），TP53突变型26例（23.2%），非特异性分子谱型44例（39.3%），4个亚型肿瘤突变负荷中位数分别为252.0、38.4、5.8及5.4 Muts/Mb ...
刘叶 +5 more
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Prevalence of adenomyosis in women with subfertility: systematic review and meta‐analysis
Ultrasound in Obstetrics &Gynecology, Volume 62, Issue 1, Page 23-41, July 2023., 2023 ABSTRACT Objective To determine the prevalence of adenomyosis in women with subfertility. Methods A systematic search was conducted in MEDLINE, EMBASE, CINAHL Plus, Google Scholar, PsycINFO and Web of Science Core Collection from database inception to October 2022. The included studies evaluated the prevalence of adenomyosis in women with subfertility,
I. Mishra +5 more
wiley +1 more source
Ultrasound in Obstetrics &Gynecology, Volume 60, Issue 5, Page 604-611, November 2022., 2022 ABSTRACT Objectives To evaluate and compare the diagnostic test accuracy (DTA) of three‐dimensional transvaginal ultrasound (3D‐TVS) and magnetic resonance imaging (MRI) for deep myometrial infiltration (DMI) and cervical invasion for preoperative staging and surgery planning in patients with endometrial cancer (EC).
G. Spagnol +9 more
wiley +1 more source
Ultrasound in Obstetrics &Gynecology, Volume 60, Issue 4, Page 477-486, October 2022., 2022 ABSTRACT Objective The aim of this systematic review and meta‐analysis was to evaluate the diagnostic accuracy of the sliding sign on transvaginal ultrasound (TVS) in detecting pouch of Douglas obliteration and bowel involvement in patients with suspected endometriosis, using laparoscopy as the reference standard.
J. L. Alcázar +6 more
wiley +1 more source
Ultrasound in Obstetrics &Gynecology, Volume 60, Issue 3, Page 381-389, September 2022., 2022 ABSTRACT Objective To evaluate the performance of third‐trimester ultrasound for the diagnosis of clinically significant placenta accreta spectrum disorder (PAS) in women with low‐lying placenta or placenta previa. Methods This was a prospective multicenter study of pregnant women aged ≥ 18 years who were diagnosed with low‐lying placenta (< 20 mm from
N. Fratelli +42 more
wiley +1 more source