Results 41 to 50 of about 2,461,179 (149)
基于血栓弹力图评价阿司匹林联合低分子肝素对子痫前期作用的实验研究
Zhongguo shiyan zhenduanxue, 2021 目的分析比较血栓弹力图和凝血五项指标评价子痫前期患者接受低分子肝素治疗后的改善效果。方法选择2019年6月—2020年6月在石家庄市妇幼保健院进行产检并确诊子痫前期的孕妇120例,采用随机数字表法随机分为两组,每组各60例。阿司匹林组给予阿司匹林治疗,联合组在阿司匹林治疗的基础上联合低分子肝素治疗,治疗周期14d。检测治疗前后两组患者的凝血五项(PT、APTT、TT、FIB、D-D)指标,血小板计数,血栓弹力图指标。同时筛选同期在医院接受产检的60例健康孕妇作为对照组,检测并比较凝血五项指标 ...
张蕾 +4 more
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Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 6, Page 749-760, June 2025.ABSTRACT Objective Placental dysfunction can result in small‐for‐gestational age (SGA) or fetal growth restriction (FGR). The aim of this prospective cohort study was to assess the association of the cerebroplacental ratio (CPR) and other more conventional fetoplacental Doppler indices, circulating placental growth factor (PlGF) levels and soluble fms ...
J. Hong +6 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2011 目的检测胎盘滋养细胞中syncytin的表达,探讨其在妊娠期高血压疾病发病中的意义。方法采用West-ern blot法测定syncytin蛋白表达强度,其中妊娠期高血压10例,重度子痫前期15例,轻度子痫前期15例,子痫组5例;正常晚期妊娠20例。结果五组均检测到syncytin蛋白的表达;子痫组syncytin蛋白表达强度最低（8.58±0.81）,重度子痫前期组（9.11±0.43）,轻度子痫前期组（10.64±0.36）,妊娠期高血压组为（11.30±2.23）,均明显低于正常晚期妊娠组（20 ...
邬俏璇, 罗炳德, 王晨虹, 周璐
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Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 5, Page 567-574, May 2025.ABSTRACT Objectives To assess the value of pregnancy‐associated plasma protein‐A (PAPP‐A) in screening for preterm pre‐eclampsia (PE) (delivery < 37 weeks' gestation) measured in maternal blood samples collected before 11 weeks, and to compare the screening performance of PAPP‐A with that of placental growth factor (PlGF) from blood samples collected ...
L. Rode +21 more
wiley +1 more source
孕妇血清妊娠相关蛋白-A及超敏C反应蛋白在子痫前期临床检测意义分析
Zhongguo shiyan zhenduanxue, 2014 目的探讨孕妇血清妊娠相关蛋白-A及超敏C反应蛋白在子痫前期的临床检测意义。方法选择我院2010年7月至2013年7月期间收治的子痫前期患者共221例,上述患者根据子痫前期严重程度分为轻度子痫前期共144例,重度子痫前期患者共77例,分别作为轻度组和重度组。同时选择在我院定期产前检测的正常孕妇50例,作为对照组。采用酶联免疫吸附实验测定血清妊娠相关蛋白A水平;采用免疫发光法测定超敏C反应蛋白水平。结果重度组和轻度组的血清超敏C反应蛋白、妊娠相关蛋白A水平分别高于对照组,差异有统计学意义 ...
邓仙桃
doaj
Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 4, Page 447-455, April 2025.ABSTRACT Objective A soluble fms‐like tyrosine kinase‐1 (sFlt‐1)‐to‐placental growth factor (PlGF) ratio cut‐off of 38 is currently considered optimal for ruling out pre‐eclampsia (PE); however, implementation of this ratio in clinical practice is limited.
M. N. Nan +15 more
wiley +1 more source
孕妇外周血中高甲基化RASSF1A基因检测对子痫前期早期预测价值的研究
Zhongguo shiyan zhenduanxue, 2019 目的通过分析子痫前期孕妇外周血中胎儿高甲基化RASSF1A基因含量的变化,探讨孕妇外周血中胎儿游离DNA水平在子痫前期中的预测诊断价值。方法收集子痫前期孕妇外周血样本32例,择同期孕龄健康孕妇30例为对照组,采用荧光定量PCR法检测孕妇外周血中高甲基化RASSF1A基因的含量,应用受试者工作特征曲线(ROC)评价高甲基化RASSF1A基因检测对轻度和重度子痫前期孕妇的诊断价值。结果轻度子痫前期组和重度子痫前期组孕妇血浆高甲基化RASSF1A基因的中位数倍值分别是正常妊娠孕妇的3.28倍和10.47倍 ...
冉贵萍 +6 more
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Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 3, Page 303-310, March 2025.ABSTRACT Objective Globally, one in four pregnant women is classified as overweight or obese, based on their prepregnancy body mass index (BMI). Obese pregnant women are at increased risk of adverse pregnancy outcomes and long‐term cardiovascular disease that occurs earlier in life.
M. Charakida +6 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2017 目的主要是为了评估高风险子痫前期妊娠期高血压患者的临床危险因素,另外还评估了子痫前期与妊娠期高血压的发病率以及复发率。方法采用队列研究获得相关数据进行分析,实验选取的孕妇包括至少含有以下一种子痫前期高风险因素:具有子痫前期的病史、临床上妊娠综合症病史、慢性高血压、糖尿病、多胎妊娠、肥胖或自身免疫性疾病。用多变量和单变量逻辑回归分析来评价高血压疾病发展过程中的临床特点和风险因素。结果 32.7%（36/110）的人患有高血压疾病,单变量分析得出子痫前期在怀孕之前是一个重要的高风险因素（OR 2.75,95%
朱君花, 雷侠
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Prediction of pre‐eclampsia using maternal hemodynamic parameters at 12 + 0 to 15 + 6 weeks
Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 2, Page 173-182, February 2025.ABSTRACT Objectives To compare the maternal hemodynamic profile at 12 + 0 to 15 + 6 weeks' gestation in women who subsequently developed pre‐eclampsia (PE) and those who did not, and to assess the screening performance of maternal hemodynamic parameters for PE in combination with the Fetal Medicine Foundation (FMF) triple test, including maternal ...
X. Wang +9 more
wiley +1 more source