Results 31 to 40 of about 2,461,178 (149)

Wada试验在癫痫外科术前评估中的应用

open access: yes, 2010
1949年日本神经科医师JuhnAtsushiWada博士在治疗精神分裂人格障碍患者时发现颈内动脉注射异戊巴比妥麻醉一侧大脑半球可以鉴定出患者的语言功能优势半球,之后Wada博士和Rasmussen博士在癫痫患者术前评估时也使用此方法为患者语言优势半球定侧 ...
马云霞, 刘献增, 孙中生
core   +2 more sources

SEEG致痫指数定位分析在顶盖癫痫中的应用

open access: yes, 2017
<正>目的总结立体定向脑电图(SEEG)证实的起始于顶盖的癫痫发作的脑电图及症状学特点并分析其致痫网络。方法回顾性分析2013年11月至2017年5月在清华大学玉泉医院癫痫中心行癫痫术前评估、并进行立体定向电极置入的7例起始于顶盖的难治性癫痫患者术前评估资料,总结其脑电图及症状学特点。应用致痫指数定位分析方法(Epileptogeniciy Mapping,EM)评价顶盖癫痫的致痫网络。EM是一种 
宋宪成   +8 more
core   +1 more source

Placental biomarker and fetoplacental Doppler abnormalities are strongly associated with placental pathology in pregnancies with small‐for‐gestational‐age fetus: prospective study

open access: yesUltrasound in Obstetrics &Gynecology, Volume 65, Issue 6, Page 749-760, June 2025.
ABSTRACT Objective Placental dysfunction can result in small‐for‐gestational age (SGA) or fetal growth restriction (FGR). The aim of this prospective cohort study was to assess the association of the cerebroplacental ratio (CPR) and other more conventional fetoplacental Doppler indices, circulating placental growth factor (PlGF) levels and soluble fms ...
J. Hong   +6 more
wiley   +1 more source

syncytin在妊娠期高血压疾病胎盘滋养细胞中的表达研究

open access: yesZhongguo shiyan zhenduanxue, 2011
目的检测胎盘滋养细胞中syncytin的表达,探讨其在妊娠期高血压疾病发病中的意义。方法采用West-ern blot法测定syncytin蛋白表达强度,其中妊娠期高血压10例,重度子痫前期15例,轻度子痫前期15例,子痫组5例;正常晚期妊娠20例。结果五组均检测到syncytin蛋白的表达;子痫组syncytin蛋白表达强度最低(8.58±0.81),重度子痫前期组(9.11±0.43),轻度子痫前期组(10.64±0.36),妊娠期高血压组为(11.30±2.23),均明显低于正常晚期妊娠组(20 ...
邬俏璇, 罗炳德, 王晨虹, 周璐
doaj  

Screening for pre‐eclampsia using pregnancy‐associated plasma protein‐A or placental growth factor measurements in blood samples collected at 8–14 weeks' gestation

open access: yesUltrasound in Obstetrics &Gynecology, Volume 65, Issue 5, Page 567-574, May 2025.
ABSTRACT Objectives To assess the value of pregnancy‐associated plasma protein‐A (PAPP‐A) in screening for preterm pre‐eclampsia (PE) (delivery < 37 weeks' gestation) measured in maternal blood samples collected before 11 weeks, and to compare the screening performance of PAPP‐A with that of placental growth factor (PlGF) from blood samples collected ...
L. Rode   +21 more
wiley   +1 more source

孕妇血清妊娠相关蛋白-A及超敏C反应蛋白在子痫前期临床检测意义分析

open access: yesZhongguo shiyan zhenduanxue, 2014
目的探讨孕妇血清妊娠相关蛋白-A及超敏C反应蛋白在子痫前期的临床检测意义。方法选择我院2010年7月至2013年7月期间收治的子痫前期患者共221例,上述患者根据子痫前期严重程度分为轻度子痫前期共144例,重度子痫前期患者共77例,分别作为轻度组和重度组。同时选择在我院定期产前检测的正常孕妇50例,作为对照组。采用酶联免疫吸附实验测定血清妊娠相关蛋白A水平;采用免疫发光法测定超敏C反应蛋白水平。结果重度组和轻度组的血清超敏C反应蛋白、妊娠相关蛋白A水平分别高于对照组,差异有统计学意义 ...
邓仙桃
doaj  

N‐terminal pro B‐type natriuretic peptide as biomarker to predict pre‐eclampsia and maternal–fetal complications

open access: yesUltrasound in Obstetrics &Gynecology, Volume 65, Issue 4, Page 447-455, April 2025.
ABSTRACT Objective A soluble fms‐like tyrosine kinase‐1 (sFlt‐1)‐to‐placental growth factor (PlGF) ratio cut‐off of 38 is currently considered optimal for ruling out pre‐eclampsia (PE); however, implementation of this ratio in clinical practice is limited.
M. N. Nan   +15 more
wiley   +1 more source

孕妇外周血中高甲基化RASSF1A基因检测对子痫前期早期预测价值的研究

open access: yesZhongguo shiyan zhenduanxue, 2019
目的通过分析子痫前期孕妇外周血中胎儿高甲基化RASSF1A基因含量的变化,探讨孕妇外周血中胎儿游离DNA水平在子痫前期中的预测诊断价值。方法收集子痫前期孕妇外周血样本32例,择同期孕龄健康孕妇30例为对照组,采用荧光定量PCR法检测孕妇外周血中高甲基化RASSF1A基因的含量,应用受试者工作特征曲线(ROC)评价高甲基化RASSF1A基因检测对轻度和重度子痫前期孕妇的诊断价值。结果轻度子痫前期组和重度子痫前期组孕妇血浆高甲基化RASSF1A基因的中位数倍值分别是正常妊娠孕妇的3.28倍和10.47倍 ...
冉贵萍   +6 more
doaj  

Association of maternal body mass index with hemodynamic and vascular alterations at 35–37 weeks' gestation

open access: yesUltrasound in Obstetrics &Gynecology, Volume 65, Issue 3, Page 303-310, March 2025.
ABSTRACT Objective Globally, one in four pregnant women is classified as overweight or obese, based on their prepregnancy body mass index (BMI). Obese pregnant women are at increased risk of adverse pregnancy outcomes and long‐term cardiovascular disease that occurs earlier in life.
M. Charakida   +6 more
wiley   +1 more source

高风险子痫前期孕妇妊娠期高血压疾病影响因素的临床研究

open access: yesZhongguo shiyan zhenduanxue, 2017
目的主要是为了评估高风险子痫前期妊娠期高血压患者的临床危险因素,另外还评估了子痫前期与妊娠期高血压的发病率以及复发率。方法采用队列研究获得相关数据进行分析,实验选取的孕妇包括至少含有以下一种子痫前期高风险因素:具有子痫前期的病史、临床上妊娠综合症病史、慢性高血压、糖尿病、多胎妊娠、肥胖或自身免疫性疾病。用多变量和单变量逻辑回归分析来评价高血压疾病发展过程中的临床特点和风险因素。结果 32.7%(36/110)的人患有高血压疾病,单变量分析得出子痫前期在怀孕之前是一个重要的高风险因素(OR 2.75,95%
朱君花, 雷侠
doaj  

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