Results 11 to 20 of about 995 (119)
Risk of pre‐eclampsia according to gestational age across three decades: population‐based study
ABSTRACT Objectives To determine the risk of pre‐eclampsia in ongoing pregnancies according to gestational age. We also studied whether the gestational‐age‐specific risks of developing pre‐eclampsia have changed over recent decades. Methods This was a population‐based study using data from the Medical Birth Registry of Norway.
C. Haavaldsen, O. Thomas, A. Eskild
wiley +1 more source
Annexin5、ET-1、vWF在子痫前期患者胎盘中的表达
目的研究子痫前期患者胎盘中Annexin5、ET-1、vWF的表达水平,并探讨子痫前期发病机制。方法采用免疫组化方法检测子痫前期患者84例(轻度29例、早发重度型27例、晚发重度型28例)及对照组29例胎盘组织中Annexin5、ET-1、vWF的表达水平。结果①胎盘中Annexin 5在子痫前期各组表达强度明显低于对照组,差异均有统计学意义(P0.05)。②胎盘中ET-1在子痫前期各组表达强度明显高于对照组,差异有统计学意义(P晚发型>轻度子痫前期患者,差异仍有统计学意义 ...
任春丽, 唐兴国, 任磊
doaj
血清TLR4及MFG-E8与子痫前期患者表达及发生早期肾损伤的关系
目的研究子痫前期患者外周血中TLR4和MFG-E8在子痫前期患者中的表达与诊断意义,并探讨其与子痫前期发生早期肾损伤的关系。方法用酶联免疫吸附法对妊娠期高血压患者30例,轻度子痫前期患者30例、重度子痫前期30例以及正常妊娠30例患者外周血中TLR4和MFG-E8表达水平。结果①外周血TLR4表达水平随病情加重呈逐渐升高趋势,sPE>mPE>GH>NP组;外周血MFG-E8表达水平随病情加重呈逐渐降低趋势 ...
任春丽 +3 more
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ABSTRACT Objectives To compare the maternal hemodynamics of Chinese women at low and at high risk for preterm pre‐eclampsia (PE) and assess the differences in hemodynamic parameters between high‐risk women with or without prophylactic aspirin. Methods This was a prospective longitudinal case–control study of 857 Chinese women with a singleton pregnancy
X. Wang +11 more
wiley +1 more source
ABSTRACT Objective To evaluate the impact of low‐dose aspirin (LDA) on placental size and uterine artery pulsatility index (UtA‐PI) by analyzing longitudinal changes between the first and second trimesters in pregnancies at high risk for early‐onset pre‐eclampsia (PE).
C. Trilla +7 more
wiley +1 more source
血浆sCD40L、sICAM-1及血管内皮损伤相关细胞与子痫前期严重程度的相关性分析
目的探讨血浆白细胞分化抗原可溶性CD40配体(sCD40L)、可溶性细胞间粘附因子-1(sICAM-1)及血管内皮损伤相关细胞与子痫前期严重程度的相关性。方法选择年龄、BMI、检测孕周等临床一般资料相匹配的重度子痫前期、轻度子痫前期患者以及健康孕妇(对照组)各45例作为研究对象,采用ELISA法检测血浆sCD40L、sICAM-1水平,采用流式细胞仪检测内皮祖细胞(EPC)、血管生成性T细胞(Tang)含量,比较并分析其相关性。结果子痫前期组的血浆sICAM-1、sCD40L水平均明显高于对照组 ...
薛峰, 颜源, 何攀
doaj
ABSTRACT Objectives To investigate the impact of aspirin administration on the incidence of preterm birth, according to the type of delivery and gestational age at preterm birth, and to examine the hypothesis that aspirin delays preterm delivery. Methods This was a secondary analysis of a multicenter stepped‐wedge cluster randomized trial of a first ...
H. H. Y. Leung +29 more
wiley +1 more source
目的探讨子痫前期对围生儿的影响。方法对2003年7月至2005年12月在我院分娩的229例子痫前期围生儿情况与随机抽取同期住院分娩的230例正常孕妇的围生儿情况进行回顾性分析。结果子痫前期早产儿、小于胎龄儿、新生儿窒息发生率及围生儿死亡率高于正常孕妇 ...
孙波, 赵艳晖, 张炜阳, 吴富菊
doaj
Assessment of risk for pre‐eclampsia at mid‐gestation to define subsequent care
ABSTRACT Objective To stratify pregnancy care based on the estimated risk of pre‐eclampsia (PE) from screening at 19–24 weeks' gestation by combinations of maternal risk factors, estimated fetal weight (EFW), mean arterial pressure (MAP) and uterine artery pulsatility index (UtA‐PI).
S. Adjahou +5 more
wiley +1 more source
基于血栓弹力图评价阿司匹林联合低分子肝素对子痫前期作用的实验研究
目的分析比较血栓弹力图和凝血五项指标评价子痫前期患者接受低分子肝素治疗后的改善效果。方法选择2019年6月—2020年6月在石家庄市妇幼保健院进行产检并确诊子痫前期的孕妇120例,采用随机数字表法随机分为两组,每组各60例。阿司匹林组给予阿司匹林治疗,联合组在阿司匹林治疗的基础上联合低分子肝素治疗,治疗周期14d。检测治疗前后两组患者的凝血五项(PT、APTT、TT、FIB、D-D)指标,血小板计数,血栓弹力图指标。同时筛选同期在医院接受产检的60例健康孕妇作为对照组,检测并比较凝血五项指标 ...
张蕾 +4 more
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