Results 91 to 100 of about 1,920 (142)

慢病毒介导shRNA静默CXCR4对Eca109细胞转移特性的影响

Zhongshan Daxue xuebao. Yixue kexue ban, 2010
【目的】 新近研究显示CXCL12/CXCR4通路在食管癌组织中有较高的表达,本研究探讨应用慢病毒介导的RNA干扰技术,有效静默食管癌细胞株Eca109细胞CXCR4的表达,研究CXCL12/CXCR4通路对食管癌Eca109细胞转移能力的影响65377;【方法】 以人CXCR4 mRNA编码序列作为干扰靶点,构建靶向CXCR4的vshRNA表达质粒,另构建不针对任何已知mRNA的阴性对照vshRNA表达质粒,转染相应组别细胞65377;研究分为控制组65380;阴性对照组及静默组65377 ...
doaj  

[Anti-inflammatory effects of cell membrane vesicle-mediated delivery of small interfering RNA targeting tumor necrosis factor-α on dental pulp stem cells]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Gao R, Ma T, Wang R, Yin Y, Li R, Wang D, Xia B.   +6 more
europepmc   +1 more source

[Efficacy of Ganciclovir Combined With Recombinant Human Interferon α-1b for Viral Encephalitis in Children]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Han B, Zhao L, Han X, Kong N, Qin X.
europepmc   +1 more source

知识图谱视角下埃博拉病毒研究态势分析 [PDF]

, 2019
吴跃伟, 马丽丽
core  

[Silencing DDX17 inhibits proliferation and migration of pulmonary arterial smooth muscle cells <i>in vitro</i> by decreasing mTORC1 activity]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Deng X, Wang J, Xiong M, Wang T, Yang Y, Li, Sun X.   +6 more
europepmc   +1 more source

MDR1 siRNA对结肠癌细胞多药耐药性的影响

Zhongshan Daxue xuebao. Yixue kexue ban, 2007
[目的]探讨MDR1 siRNA对结肠癌细胞多药耐药性的影响。[方法]设计合成两种针对MDR1 mRNA的siRNA双链分子（#4123 MDR1 siRNA和#4029 MDR1 siRNA）,并转染入COLO 320DM和HT-29结肠癌细胞,观察其对结肠癌细胞MDR1 mRNA和P-gp表达的影响。并分别与5-FU、阿霉素和长春新碱等抗肿瘤药联用,观察结肠癌细胞活力的变化。用阿霉素处理后,观察转染MDR1 siRNA结肠癌细胞的细胞内阿霉素累积浓度的变化。RT-PCR检测细胞MDR1 ...
doaj  

[Protective effect of knock-down the expression of <i>Blimp1</i> gene on early liver injury in CCl₄-induced mouse model of liver fibrosis]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Qin Q, Li R, Zhou Y, Zhang Y, Han M, Zhu L.   +5 more
europepmc   +1 more source

[Clinical research advances for small-molecule nucleic acid drugs in the treatment of chronic hepatitis B]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Wang WX, Guo YM, Fei ZX, Zhu SS, Wang FS.   +4 more
europepmc   +1 more source

[Comparison of antiviral efficacy of nucleos(t)ide analogue monotherapy and its combination with interferon-α in children 1-6 years-old with HBeAg-positive chronic hepatitis B]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Wang ZW, Dong Y, Ouyang WX, Cao LL, Pang L, Xu HM, Yan JG, Zhu Y, Xu Y, Fu JL, Wang FS, Zhang M.   +11 more
europepmc   +1 more source

[Progress in clinical research related to viral hepatitis in 2025]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Ding Y, Li Y, Dou XG.
europepmc   +1 more source