Influencing Factors of Glycemic Variability in Type 1 Diabetes Patients [PDF]
BackgroundThe prevalence of T1DM (type 1 diabetes) is increasing year by year, and its autoimmunity can easily lead to the destruction of pancreaticβcells and insulin deficiency, making blood glucose difficult to reach the target.ObjectiveTo ...
HE Yan, ZHAO Songqing
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Association between Subclinical Hypothyroidism and Cardiac Autonomic Neuropathy in Type 2 Diabetes Mellitus [PDF]
BackgroundCardiac autonomic neuropathy (CAN) is a common and severe chronic diabetic complication, whose association with thyroid function has rarely been reported.ObjectiveTo investigate the association between subclinical hypothyroidism and CAN in type
ZHAO Lei, LI Ruqiang, YUAN Mingxia
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早期糖尿病肾病血清β2-微球蛋白、尿微量白蛋白测定的临床意义 [PDF]
目的:回顾性分析β2-微球蛋白、尿微量白蛋白表达及诊断情况与糖尿病肾病病情发展情况相关性,从而明确二者在早期糖尿病肾病中的诊断价值。方法:选取2016年5月-2017年10月在笔者所在医院治疗的糖尿病患者100例,将该100例患者按临床诊断分为临床无肾病组、早期肾病组、临床肾病组。选取40例来笔者所在医院做健康体检的正常个体作为对照组。对糖尿病肾病患者及正常个体血清β2-微球蛋白、尿微量白蛋白进行检测并进行对比分析。结果:血液检测中,对照组血清β2-微球蛋白水平为(2.24±1.08)mg/L ...
廖蕴惠, 赵军
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沙格列汀联合小剂量厄贝沙坦对30例早期糖尿病肾病患者预后的影响 [PDF]
目的观察沙格列汀联合小剂量厄贝沙坦对早期糖尿病肾病患者预后的影响。方法 2017年6月—2018年3月选取该院60例早期糖尿病肾病患者为研究对象,随机分为治疗组(30例)与对照组(30例),对照组予以常规治疗+厄贝沙坦口服治疗,治疗组在对照组的基础上予以沙格列汀口服治疗,两组疗程均为3个月。检测两组患者治疗前后空腹血糖(GLU)、血清尿素氮水平、血清肌酐浓度以及瘤坏死因子-α(TNF-α)、超敏C-反应蛋白(hs-CRP)、白细胞介素-6(IL-6)炎性因子水平 ...
肖国鸣
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Is the Change of Cytokines Related to Renal Damage in Children with IgA Vasculitis? [PDF]
BackgroundThe long-term prognosis of IgA vasculitis (IgAV) depends on thedegreeof renal damage. Studies on the pathogenesis of renal injury in IgAV have found that cytokines play an important role in mediating and driving the process of renal damage ...
WANG Mengdi, DU Yue
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Identification of pathogenic mutations for a Wolfram syndrome pedigree by whole exome sequencing and analysis of its clinical characteristics [PDF]
Objective·To identify the causative gene and mutations and describe the clinical traits in a Chinese diabetes pedigree suspected of Wolfram syndrome.Methods·A total of 12 subjects from one family were included.
CHEN Xianghui +9 more
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The Efficacy of Whole Course Management in Patients with Schizophrenia [PDF]
BackgroundSchizophrenia is a common mental disease with high rates of recurrence and disability. The therapeutic effects of antipsychotic drugs monotherapy are insufficient on improving patients' ability to daily life and social functioning, with ...
ZULAYETI•Tuerxun, ZHANG Guiqing, YAO Yongkun, LU Keke
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Differences of Community Health Service Quality Evaluation in China and Abroad:a Systematic Review [PDF]
BackgroundIn China, the assessment of community health services has been increasingly valued as the development of such services advances, but relevant research is still at the exploratory stage. Therefore, establishing a community health service quality
ZHANG Qianqian, JIN Hua, YU Dehua
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Prospects and challenges of selectivity proteinuria index in clinical practices [PDF]
Plasma proteins are selectively filtrated by glomerular filtration membrane due to their sizes and charge barriers. By comparing renal clearance of a larger molecular weight to a smaller molecular weight protein in plasma, selectivity proteinuria index ...
Bing Dai, Qi-liang Chen
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Influence of transient receptor potential cation channel 6 on renal tubulointerstitial inflammation in mice with diabetic kidney disease and its mechanism [PDF]
Objective To investigate the influence of transient receptor potential cation channel 6 (TRPC6) on renal tubulointerstitial inflammation in mice with diabetic kidney disease (DKD) and its mechanism. Methods A total of 36 male C57/BL6J mice, aged 6 weeks,
LIU Congcong, ZHANG Xingjian, DING Lin, ZHANG Yao, ZHANG Dongjie, MA Ruixia
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