Results 11 to 20 of about 3,592 (157)

Combined detection of urinary biomarkers noninvasively predicts extent of renal injury in patients with early diabetic kidney disease with kidney qi deficiency syndrome: A retrospective investigation

The Anatomical Record, Volume 306, Issue 12, Page 2945-2957, December 2023., 2023
Abstract Incipient diagnosis and noninvasive forecasts using urinary biomarkers are important for preventing diabetic kidney disease (DKD) progression, but they are also controversial. Previous studies have shown a potential relationship between urinary tubular biomarkers (UTBs) and traditional Chinese medicine (TCM) syndrome in patients with DKD. Thus,
Wei Wu, Xian‐Jie Meng, Bing‐Ying Wan, Qi‐Jun Fang, Ying‐Lu Liu, Jie Wang, Yan Fu, Can‐Can Yuan, Mei‐Zi Wang, Fee‐Lan Chong, Yi‐Gang Wan, Shan‐Mei Shen   +11 more
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Fatty acid β‐oxidation and mitochondrial fusion are involved in cardiac microvascular endothelial cell protection induced by glucagon receptor antagonism in diabetic mice 脂肪酸β‐氧化和线粒体融合参与胰高血糖素受体拮抗剂对糖尿病小鼠心脏微血管内皮细胞的保护作用

Journal of Diabetes, Volume 15, Issue 12, Page 1081-1094, December 2023., 2023
Highlights Glucagon receptor (GCGR) monoclonal antibody (mAb) improves cardiac function and attenuates microvascular damage in db/db mice. GCGR mAb ameliorates the oxidative stress of cardiac microvascular endothelial cells in diabetic mice. GCGR mAb counteracts the diabetes‐induced upregulation of carnitine palmitoyltransferase 1B, optic atrophy type ...
Peng Wang, Rui Wei, Xiaona Cui, Zongzhe Jiang, Jin Yang, Lingyun Zu, Tianpei Hong   +6 more
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Use of basal insulin in the management of adults with type 2 diabetes: An Asia‐Pacific evidence‐based clinical practice guideline 使用基础胰岛素治疗成人2型糖尿病:亚太地区循证临床实践指南

Journal of Diabetes, Volume 15, Issue 6, Page 474-487, June 2023., 2023
Highlights This is a systematic review‐based clinical practice guideline. After internal and external review, two strong recommendations, six conditional recommendations, and one qualifying statement were made for insulin‐naive adult patients with type 2 diabetes.
Linong Ji, Yingying Luo, Yong Mong Bee, Jun Xia, Khue Thy Nguyen, Weigang Zhao, Liming Chen, Siew Pheng Chan, Chaicharn Deerochanawong, Soo Lim, Daisuke Yabe, Margaret McGill, Ketut Suastika, Xiaoying Li, Alice Pik Shan Kong, Wei Chen, Zhan Zhao, Chenchen Xu, Marisa Deodat, Xiaomei Yao   +19 more
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Sex differences in risk factors for end‐stage kidney disease and death in type 2 diabetes: A retrospective cohort study 2型糖尿病终末期肾病和死亡危险因素的性别差异:一项回顾性队列研究

Journal of Diabetes, Volume 15, Issue 3, Page 246-254, March 2023., 2023
Highlights Sex differences are observed in the progression of chronic kidney disease; however, it is uncertain whether sex is associated with the risk of kidney failure in type 2 diabetes. In this multicenter cohort study, men had a higher risk of end‐stage kidney disease (ESKD) than women, and moderately increased albuminuria was strongly associated ...
Megumi Oshima, Yasunori Iwata, Tadashi Toyama, Shinji Kitajima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kengo Furuichi, Masakazu Haneda, Tetsuya Babazono, Hiroki Yokoyama, Kunitoshi Iseki, Shinichi Araki, Toshiharu Ninomiya, Shigeko Hara, Yoshiki Suzuki, Masayuki Iwano, Eiji Kusano, Tatsumi Moriya, Hiroaki Satoh, Hiroyuki Nakamura, Hirofumi Makino, Takashi Wada   +22 more
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Assessment of subclinical left ventricular systolic dysfunction in patients with type 2 diabetes: Relationship with HbA1c and microvascular complications 2型糖尿病患者亚临床左心室收缩功能障碍的评估:与糖化血红蛋白和微血管并发症的关系

Journal of Diabetes, Volume 15, Issue 3, Page 264-274, March 2023., 2023
Highlights In asymptomatic type 2 diabetic patients with preserved left ventricular ejection fraction, a negative correlation of glycated hemoglobin with subclinical left ventricular systolic dysfunction was revealed. Furthermore, glycated hemoglobin may make prognostic significance for the progression of myocardial damage. Abstract Background We aimed
Yanyan Chen, Ying Zhang, Yi Wang, Shengjun Ta, Min Shi, Yingni Zhou, Mengying Li, Jianfang Fu, Li Wang, Xiangyang Liu, Zuowei Lu, Liwen Liu, Zeping Li, Jie Zhou, Xiaomiao Li   +14 more
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Electroacupuncture reduces blood glucose by regulating intestinal flora in type 2 diabetic mice 电针通过调节2型糖尿病小鼠肠道菌群降低血糖

Journal of Diabetes, Volume 14, Issue 10, Page 695-710, October 2022., 2022
Highlights Electroacupuncture (EA) regulates the intestinal flora by promoting intestinal motility. EA regulated the intestinal flora to reduce the level of systemic inflammation. EA lowering the blood glucose by the IKKβ/NF‐κB‐JNK‐IRS‐1‐AKT signal pathway.
Jing An, Lingli Wang, Shuangning Song, Lugao Tian, Qingqing Liu, Minhui Mei, Wenhua Li, Shi Liu   +7 more
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Evaluation and redesign of the primers for detecting nitrogen cycling genes in environments

Methods in Ecology and Evolution, Volume 13, Issue 9, Page 1976-1989, September 2022., 2022
Abstract A better understanding of how nitrogen (N) cycling genes are involved in ecological processes is one of the crucial areas of microbial ecology. Currently, most molecular biological techniques investigating N cycling genes in the environment heavily rely on the accuracy of the polymerase chain reaction (PCR) primers; however, their specificity ...
Zhujun Wang, Kai Feng, Ziyan Wei, Yueni Wu, Kazuo Isobe, Keishi Senoo, Xi Peng, Danrui Wang, Qing He, Xiongfeng Du, Shuzhen Li, Yan Li, Ye Deng   +12 more
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Lipid variability and risk of microvascular complications in Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial: A post hoc analysis 控制糖尿病心血管风险的行动(ACCORD)试验中的血脂变异性和微血管并发症风险:一项事后分析

Journal of Diabetes, Volume 14, Issue 6, Page 365-376, June 2022., 2022
HighlightsAssociation of lipid variability with diabetic microvascular complications. Abstract Background Greater lipid variability may cause adverse health events among diabetic patients. We aimed to examine the effect of lipid variability on the risk of diabetic microvascular outcomes among type 2 diabetes mellitus patients.
Daniel Nyarko Hukportie, Fu‐Rong Li, Rui Zhou, Jia‐Zhen Zheng, Xiao‐Xiang Wu, Meng‐Chen Zou, Xian‐Bo Wu   +6 more
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Effects of SGLT2 inhibitors on patients with diabetic kidney disease: A preliminary study on the basis of podocyturia SGLT2抑制剂对糖尿病肾病患者的影响:基于尿足细胞的初步研究

Journal of Diabetes, Volume 14, Issue 4, Page 236-246, April 2022., 2022
Highlights Diabetic kidney disease is a progressive disease with the pathology of glomerular damage and loss of podocytes. Sodium glucose cotransporter 2 inhibitors (SGLT2i) can be expected to decrease the amount of podocyte excretion. Male patients receiving SGLT2i have better diabetic kidney disease‐related parameters and podocyturia levels. Abstract
Emre Durcan, Serbay Ozkan, Halil Ibrahim Saygi, Mevlut Tamer Dincer, Ozge Polat Korkmaz, Serdar Sahin, Cebrail Karaca, Cem Sulu, Alev Bakir, Hande Mefkure Ozkaya, Sinan Trabulus, Elif Guzel, Nurhan Seyahi, Mustafa Sait Gonen   +13 more
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A study on the status of normoalbuminuric renal insufficiency among type 2 diabetes mellitus patients: A multicenter study based on a Chinese population 正常蛋白尿的2型糖尿病患者肾功能不全状况的研究:基于中国人群的多中心研究

Journal of Diabetes, Volume 14, Issue 1, Page 15-25, January 2022., 2022
Highlights Approximately 63.6% of diabetes patients with an estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m2 have normal albuminuria. The factors related to normoalbuminuria and eGFR < 60 mL/min/1.73 m2 were male sex, older age, higher triglyceride levels, lower extremity arterial disease, and a longer duration of diabetes. Compared with
Xiaomeng Jia, Li Zang, Ping Pang, Lina Jiang, Jin Du, Weijun Gu, Jianming Ba, Yiming Mu, Zhaohui Lyu   +8 more
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