Results 11 to 20 of about 3,663 (117)
Journal of Diabetes, Volume 15, Issue 10, Page 866-880, October 2023., 2023 Highlights Nattokinase rescued endothelial dysfunction and pericyte loss in the diabetic retina. Nattokinase attenuated diabetes‐induced retinal inflammation and neurodegeneration. High mobility group box 1 signaling was involved in nattokinase‐mediated retinal protection.
Zijing Huang +11 more
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Veterinary Dermatology, Volume 34, Issue 4, Page 327-338, August 2023., 2023 Background – The caninised monoclonal antibody lokivetmab (LKV), directed at interleukin (IL)‐31, is very effective at controlling pruritus in most dogs with atopic dermatitis (AD). However, evidence exists that IL‐31 is not required for the induction of acute allergic skin inflammation, which might explain why this treatment is less efficacious in ...
Chie Tamamoto‐Mochizuki +4 more
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Journal of Diabetes, Volume 15, Issue 2, Page 165-180, February 2023., 2023 Highlights For the first time, our study contributed a systematic evaluation of bile acid (BA) profiles in plasma, feces and liver tissue and gut microbiota changes triggered by fasting‐refeeding cycle in mice. Our work clearly demonstrated that overnight fasting leads to significant, but reversible changes in BA profiles and gut microbiota composition.
Yi Zhang +16 more
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Journal of Diabetes, Volume 14, Issue 10, Page 695-710, October 2022., 2022 Highlights Electroacupuncture (EA) regulates the intestinal flora by promoting intestinal motility. EA regulated the intestinal flora to reduce the level of systemic inflammation. EA lowering the blood glucose by the IKKβ/NF‐κB‐JNK‐IRS‐1‐AKT signal pathway.
Jing An +7 more
wiley +1 more source
Glomerular cell cross talk in diabetic kidney diseases 糖尿病肾病中肾小球细胞间的相互作用
Journal of Diabetes, Volume 14, Issue 8, Page 514-523, August 2022., 2022 Highlights Glomerular cell cross talk is essential for maintaining the glomerular filtration barrier. In‐depth exploration of intraglomerular signaling pathway changes during diabetic kidney disease may help discover new therapeutic targets. Abstract Diabetic kidney disease (DKD) is a severe microvascular complication of diabetes mellitus.
Ruixue Dong, Youhua Xu
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Ultrasound in Obstetrics &Gynecology, Volume 58, Issue 6, Page 900-908, December 2021., 2021 ABSTRACT Objective Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) vertical transmission has been investigated extensively. Recently, the World Health Organization (WHO) published strict criteria to classify the timing of mother‐to‐child transmission of SARS‐CoV‐2 into different categories.
R. Sevilla‐Montoya +23 more
wiley +1 more source
Veterinary Dermatology, Volume 32, Issue 4, Page 331-e92, August 2021., 2021 Background MicroRNAs (miRNA) are short, single‐stranded RNA molecules that regulate gene expression in a post‐transcriptional manner. Their expression is proposed to be tissue‐specific and alterations in miRNA expression have been detected in many diseases. Objective To compare miRNA expression in the skin of healthy Labrador and golden retrievers, and
Marie Isabel Morlang +3 more
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微粒体在缺血性卒中的作用 The Role of Microparticles in Ischemic Stroke
Zhongguo cuzhong zazhi, 2019 【摘要】 在血管内皮功能障碍、急慢性血管炎症和高凝状态下均可发现由血小板、白细胞和内皮细胞释放的微粒体。不同种类的微粒体在缺血性卒中病理过程中的作用有所不同：缺血性卒中患者外周血白细胞微粒升高，高水平的白细胞微粒体能加重血管内皮细胞损伤，血浆中长期及高水平的血小板微粒体可诱导微血管血栓形成。另外，不同种类的微粒体均能反映血管内皮损伤的程度，诱导内皮细胞功能失调，加重内皮功能障碍，同时微粒体中携带的信使RNA和微小核糖核酸等能促进内皮细胞增殖，促进动脉粥样硬化斑块内新生血管生成，使斑块更易破裂出血。
周蕾，吴冬雨，姚小梅，时彦莹，朱宪策，黄晶，王春雪，张宁
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Journal of Diabetes, Volume 12, Issue 3, Page 224-236, March 2020., 2020 Highlights Diabetic conditions induce compositional dysbiosis of the gut microbiota and impair gut barrier integrity. Diabetic conditions markedly downregulate the abundance of Faecalibacterium prausnitzii in the gut. Under diabetic conditions, microbial anti‐inflammatory molecules from Faecalibacterium prausnitzii restore the gut barrier and ZO‐1 ...
Jihao Xu +7 more
wiley +1 more source
主动脉夹层患者血清中miR-20、miR-15a水平与预后关系
Zhongguo shiyan zhenduanxue, 2021 目的探究微小RNA-20(miR-20)、微小RNA-15a(miR-15a)在主动脉夹层患者血清中的表达水平及两者与预后的关系。方法选取2015年4月至2018年7月于本院确诊的109例主动脉夹层患者为研究对象,称患病组,并将同期106例健康体检者作为对照,为健康组。以实时荧光定量PCR法检查所有受试者血清中miR-20、miR-15a表达水平;分析两组不同预后患者一般资料及血清中miR-20、miR-15a水平;采用Logistic回归分析影响主动脉夹层预后的因素;利用受试者工作特征曲线(ROC ...
李亮 +6 more
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