【目的】测定不同周期 STZ 诱导糖尿病生存信号改变对心肌缺血/再灌注( I/R) 损伤及心肌细胞凋亡的影响。【方法】阻断和开放左冠状动脉前降支建立大鼠急性心肌 I/R 模型, 用 TTC 染色, 测定大鼠心肌 I/R 后梗死面积, 用免疫印迹法定量分析代表心肌凋亡水平的 caspase- 3 及代表细胞生存信号的磷酸化蛋白激酶B(P- Akt)的表达, 用槽式电泳法测定硝基酪氨酸。【结果】在 STZ 处理后 2 周, 糖尿病组(2WD)心肌梗死面积比相应周期对照组(2WC)明显缩小, STZ 处理后 ...
doaj
[Medical treatment standards for emergency trauma wounded (2025 edition)]. [PDF]
National Health Commission Of The People's Republic Of China.
europepmc +1 more source
STZ诱导糖尿病大鼠心肌VEGF表达及血管密度变化对缺血再灌注损伤的影响
[目的]测定不同周期STZ诱导的糖尿病对心肌缺血,再灌注(I/R)损伤的影响及其与心肌VEGF表达及冠脉血管密度变化的关系。[方法]阻断和开放左冠状动脉前降支建立大鼠急性心肌I/R模型。分别用,TTC染色、免疫印迹分析及Morphometric分析方法,测定大鼠心肌I/R后梗死面积、VEGF表达及冠脉血管密度。[结果]STZ处理后2周,糖尿病组(2WD)心肌梗死面积比相应周期对照组(2WC)明显缩小;STZ处理后16周(16WD),梗死面积比相应对照组(16WC)增加;Morphometric分析显示 ...
doaj
[Clinical efficacy of multidisciplinary team collaboration in the treatment of deep sternal wound infection]. [PDF]
Tong L +6 more
europepmc +1 more source
One case of sinus tachycardia caused by domestic mercury intoxication [PDF]
WANG Chunhua
core +1 more source
[Advances in liver transplantation technology]. [PDF]
Zhu ZJ.
europepmc +1 more source
[Effects of ultrathin inguinal flap free transplantation in repairing hand and foot wounds]. [PDF]
Zhang WD +6 more
europepmc +1 more source
[Construction of cardiac organoids derived from human induced pluripotent stem cells for cardiac disease modeling and drug evaluation]. [PDF]
Gong X, Fan Y, Luo K, Yan Y, Li Z.
europepmc +1 more source
[Medical treatment standards for emergency burn wounded (2025 edition)]. [PDF]
National Health Commission Of The People's Republic Of China.
europepmc +1 more source
[Establishment of a canine model of vascularized allogeneic spinal cord transplantation and preliminary study on spinal cord continuity reconstruction]. [PDF]
Chen J +6 more
europepmc +1 more source

