Results 11 to 20 of about 1,172 (144)
Study on the action mechanism of lncRNA MIAT/miR-384-5p in rats with acute myocardial infarction [PDF]
Objective To investigate the role and molecular mechanism of lncRNA MIAT inhibition in acute myocardial infarction (AMI) in rats. Methods Sixty male Sprague-Dawley (SD) rats were randomly divided into sham, AMI, AMI+si-NC, AMI+si-MIAT, AMI+si-MIAT+miR-NC
CHEN Huibin, JIAN Jie, LI Can
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Zhongguo shiyan zhenduanxue, 2022 目的 观察竹节参总皂苷对大鼠心肌缺血再灌注损伤的影响及机制。方法 将雄性Wistar大鼠随机分为5组:假手术组、模型组、地奥心血康组50.0mg·kg-1、竹节参总皂苷50.0mg·kg-1组及100.0mg·kg-1组。结扎大鼠心脏冠状动脉左前降支(LDA)30min再灌注120min,制备心肌缺血再灌注损伤模型,取血及心肌组织。利用生物试剂盒检测血清中天门冬酸氨基转移酶(AST)、乳酸脱氢酶(LDH)、丙二醛(MDA)、超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)的含量 ...
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PPARγ激动剂罗格列酮对大鼠心肌缺血-再灌注心律失常的影响 [PDF]
, 2007 【目的】探讨PPARγ激动剂对大鼠心肌缺血-再灌注心律失常的影响及相关机制。【方法】将雄性SD大鼠60只随机分成假手术（Sham）组、缺血再灌注（I／R）组、缺血再灌注＋罗格列酮（I／R＋Ros）组、缺血再灌注＋罗格列酮＋缓激肽B2受体拮抗剂HOE140（I／R＋Ros＋HOE140）组，每组15只。麻醉大鼠后，结扎大鼠冠状动脉前降支根部30min，再灌注40min，观察缺血再灌注前后心律失常发生情况，检测肌组织丙二醛（MDA）、超氧化物歧化酶（SOD）、总一氧化氮合酶（tNOS）、还原型一氧化氮合酶 ...
冯冲 +5 more
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Efficacy and Safety Combined with Conventional and Western Medicine Treatments on Coronary Heart Disease Complicated with Heart Failure：a Systematic Review [PDF]
, 2022 BackgroundAnti-atherosclerotic and anti-heart failure therapies are the key to the treatment of coronary heart disease (CHD) , a common cardiovascular disease.
WANG Tianyuan, WANG Yanbo, FENG Shuo, HU Jing, ZHANG Huina, WANG Hong, LI Bo
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藏药镰形棘豆的化学成分、药理作用及毒理学研究进展 [PDF]
, 2016 目的:为进一步研究和开发利用藏药镰形棘豆提供参考。方法:以"镰形棘豆""莪达夏""化学成分""药理作用""毒理学""Oxytropis""Oxytropis falcata""Oxytropis falcata Bunge""Chemical constituents""Chemical composition""Pharmacologic actions""Toxicology"等为关键词,组合查询2010年1月-2016年2月在Pub Med、中国知网、万方、维普等数据库中的相关文献 ...
刘晓玲 +4 more
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Function of Apoptosis and Autophagy in Cardiovascular Diseases [PDF]
, 2017 细胞凋亡与自噬是普遍存在于各种细胞内的生命现象,广泛参与了机体的生理、病理过程,且二者有着多因子、多通路的相互影响,这种错综复杂的关系贯穿于各种心血管疾病的始终,对多种心血管疾病的发生发展转归起重要作用。现对细胞凋亡与自噬及其相互关系进行梳理,并综述其在心血管疾病中的作用。Apoptosis and autophagy are common life phenomenon in various cells, which widely involve in physiological and ...
杨雅瑾, 林小凤, 费燕, 陈尚瑜
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Zhongguo shiyan zhenduanxue, 2010 目的观察在体大鼠心肌缺血不同时间后再灌注120 min的心肌酶学与超微结构变化,评价缺血时间对再灌注损伤形成的影响。方法结扎大鼠左冠状动脉前降支（LAD）15 min、30 min、60 min,以及分别再灌注120 min,造成心肌缺血和缺血/再灌注。自腹主动脉取血检测血清肌酸激酶同工酶（CK-MB）、乳酸脱氢酶（LDH）、天门冬酸氨基转移酶（AST）,采用透射电镜观察心肌细胞超微结构变化。结果单纯缺血15 min及缺血15 min再灌注120 min心肌损伤不明显,两组血清心肌酶无显著性变化 ...
崔新明 +6 more
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Recent Developments in Stem Cells from Human Exfoliated Deciduous Teeth in the Treatment of Non-oral Diseases [PDF]
, 2023 Stem cells from human exfoliated deciduous teeth (SHEDs) are odontogenic stem cells with strong proliferation ability and multilineage differentiation potential.
JIANG Zhihan, XU Ling
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Optimization of Ultrahigh Pressure Assisted Micellar Extraction of Taxifolin from Larch [PDF]
, 2023 In this study, in order to simplify the extraction process of taxifolin, cut costs and energy sources, improve extraction efficiency, and promote comprehensive application of taxifolin.
Fan YANG +3 more
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Research progress in extraction technology and biological activity of oleuropein [PDF]
, 2023 The review summarized the latest domestical and international research progress in the biosynthesis pathway, safety, extraction process, and biological activity of oleuropein in recent years. The problems in the olive industry was analyzed and its future
CHU Zejun +5 more
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