慢性阻塞性肺疾病合并肺炎链球菌肺炎患者BCL-2表达水平及对肺功能的影响研究
Zhongguo shiyan zhenduanxue, 2019 慢性阻塞性肺疾病(COPD)能够增加患者终末期肺功能衰竭的发生风险,流行病学研究显示,COPD的发病率可达233-455/10万人左右[1,2],特别是在长期吸烟或者具有肺气肿等疾病的人群中,COPD的发病率可进一步上升。细胞凋亡或者增殖平衡的紊乱,是促进血管内皮细胞、平滑肌细胞损伤,并诱导下游炎症反应富集的重要因素。抗凋亡因子BCL-2的表达,能够通过平衡BAX蛋白的表达,拮抗凋亡蛋白的表达,抑制细胞的凋亡,减轻支气管内皮细胞的损伤,保护支气管内皮的完整性,进而保护内皮下组织,降低肺气肿的发生风险 ...
侯晓俊 +4 more
doaj
Diagnosis and Treatment of Tracheal or Bronchuotracheal Adenoid Cystic Carcinoma [PDF]
, 2010 Background and objective Adenoid cystic carcinoma is primary bronchopulmonary carcinoma with low malignancy, and 43 patients treated in the past 50 years in our hospital were retrospectively studied.
Daping YU +5 more
core
小儿支气管哮喘后血清25-羟基维生素D3浓度与气道高反应性和机体变态反应指标的关系研究
Zhongguo shiyan zhenduanxue, 2019 支气管哮喘是我国最普遍疾病之一,是特殊变应原引发的以气道炎症、气道高反应（AHR）和气道可逆性阻塞为特征的慢性疾病[1]。支气管哮喘可在任何年龄段发生,大多集中发生于5岁之前。小儿支气管哮喘（infantile bronchial asthma）的反复发作不仅损害患儿肺功能,还会影响患儿生长发育与生活质量[2 ...
魏杰男, 刘兰, 韩芳
doaj
慢性阻塞性肺疾病患者血清IgE含量与支气管舒张试验临床相关性
Zhongguo shiyan zhenduanxue, 2008 目的探讨慢性阻塞性肺疾病患者血清IgE含量与支气管舒张试验临床相关性。方法取67例COPD患者,血清用散射速率比浊法测定其IgE含量,并进行FEV1及其改善率测定,对所得数据进行统计学分析。结果IgE值与FEV1进行相关性分析和显著性检验呈负相关（r=-0.301 ...
赵贺秋, 赵颂秋
doaj
[Periodontitis Aggravates Chronic Obstructive Pulmonary Disease Progression by Promoting Pulmonary Macrophage M1 Polarizations]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanLi J +5 more
europepmc +1 more source
[Research Progress on the Regulatory Mechanism of Respiratory Microbiota in the Comorbidity of Chronic Obstructive Pulmonary Disease and Lung Cancer]. [PDF]
Zhongguo Fei Ai Za ZhiZhang Y, Zhang T, Wang H.
europepmc +1 more source
Endothelial progenitor cells and chronic obstructive pulmonary disease: From basic research to clinical application. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue BanHe X, Zeng H, Chen Y.
europepmc +1 more source
[Therapeutic effects of natural products on animal models of chronic obstructive pulmonary disease]. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue BanFei X +5 more
europepmc +1 more source
CXCL12 is a potential therapeutic target for type 2 diabetes mellitus complicated by chronic obstructive pulmonary disease. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoXu H, Weng L, Xue H.
europepmc +1 more source
[Using Xiaoqinglong Decoction to Treat Acute Exacerbation of Chronic Obstructive Pulmonary Disease Presenting External Cold and Internal Fluid Retention Syndrome: Observation of the Clinical Efficacy]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanTang W +5 more
europepmc +1 more source