Results 51 to 60 of about 16,417 (175)
Characterization and function analysis of DNA replication enzymes from Hyperthermophilic archaea Palaeococcus pacificus DY20341 [PDF]
, 2016 DNA是至今发现的绝大多数生物遗传信息的携带者。DNA复制机制保证了细胞分裂期间遗传信息的复制和传递，是维持生物遗传稳定性的前提。DNA复制过程涉及几十种蛋白和酶的参与以确保遗传信息被准确而及时的复制。 研究DNA复制对人类疾病，特别是肿瘤及传染病的机理探索有至关重要的意义。然而参与真核生物(包括人类)DNA复制的酶系非常复杂，对真核生物DNA复制机制的研究面临着诸多挑战。细菌的DNA复制系统相对简单，但其复制酶系与真核生物差别较大。古菌的复制酶系与真核生物的复制酶系相似，而且相对简单 ...
赵文昭
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Conservation Biology, Volume 40, Issue 2, April 2026.Scaling area‐based conservation, including initiatives led or comanaged by Indigenous Peoples and local communities, is a flagship goal of the Kunming‐Montreal Global Biodiversity Framework. Conservationists often aspire to scale initiatives, but this is rarely achieved in practice. Identifying and addressing factors that limit initiative adoption (i.e.
Thomas Pienkowski +39 more
wiley +1 more source
Mechanisms of activity hepatic stellate cells induced myeloid-derived suppressor cells accumulation and migration [PDF]
, 2015 原发性肝癌（hepatocellularcarcinoma，HCC）是全球第五大常见的恶性肿瘤，在肿瘤致死的病因中排名第三位。在全球，每年有超过50万人死于肝癌，且一半以上在中国。随着科学研究的发展，科研人员发现肝癌的发生发展不仅仅是病毒感染、环境因素、基因突变这些因素，肿瘤微环境对肿瘤的发生、发展、复发转移有着重要作用。肝脏是一个具有“免疫特赦”的脏器，肝癌微环境中的非实质细胞及其细胞因子是肝癌的免疫逃逸，复发转移的重要因素。 肝星状细胞（hepaticstellatecell，HSCs ...
许雅苹
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Conservation Biology, Volume 40, Issue 2, April 2026.Abstract Illegal wildlife trade (IWT) is one of the largest global illegal activities, and it negatively affects biodiversity and sustainable development worldwide. DNA barcoding coupled with high‐throughput sequencing (i.e., metabarcoding) is useful in identifying taxa affected by IWT and has been used routinely for decades.
Maria Joana Ferreira da Silva +9 more
wiley +1 more source
hsa-miR-125a-5p Enhances Invasion Ability in Non-Small Lung Carcinoma Cell Lines [PDF]
, 2009 Background and objective MicroRNAs (miRNAs) are short non-coding RNAs that posttranscriptionally regulate gene expression by partially binding complementary to target sites in mRNAs.
Enhua WANG +4 more
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Hobbyist preferences for pet freshwater turtles
Conservation Biology, Volume 40, Issue 2, April 2026.Abstract The burgeoning pet trade is a primary threat to wild freshwater turtles worldwide. Although the risks from commercial exploitation of turtles have been discussed widely, there is little empirical research on preferences for pet turtles from a hobbyists’ perspective.
Jingjing Zhao +7 more
wiley +1 more source
Gaoya dianqi, 1997 利用动态图象高速微机采集系统,对纵向磁场线圈触头真空电弧形态进行了研究,触头开距从10mm到40mm变化,得出在相同电弧电流下,电弧扩散区域随开距增加而增加;电弧电压随开距增加而呈线性增加;弧柱电弧电场强度随开距增加而减少。这说明在长开距下,由于弧柱表面积增加,扩散到弧柱外的电子、离子和金属粒子相应增多,因而使输入到弧隙的能量增加以加热触头表面和加强粒子的扩散。
武建文, 王毅, 王季梅
doaj
"fordi før så skreiv æ Å-G". En studie om andreklassingers valg av stavemåter.
, 2023 The purpose of this master's thesis has been to look at the choices students in Year 2 make when spelling words. The students participating in this research are in the transition between phonological and orthographic writing, and the study will focus on how these students adopt different spelling strategies. The assignment's data material is taken from
openaire +1 more source
, 2012 利用泥鳅(Misgurnus anguillicaudatus)的微卫星引物跨种扩增大鳞副泥鳅(Paramisgurnus dabryanus),通过家系扩增、PCR产物测序筛选出6个座位,用于大鳞副泥鳅7个野生群体的遗传结构分析。结果显示,群体的平均等位基因数在3.167～4.833,平均观测杂合度(Ho)在0.248～0.417,平均期望杂合度(He)在0.379～0.505,多个座位存在零等位基因、杂合子缺失现象,显示大鳞副泥鳅种群遗传多样性较低。采用UPGMA法对7个群体基于DA遗传距离进行聚类,
俞小牧, 游翠红, 童金苟
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Zhongshan Daxue xuebao. Yixue kexue ban, 1992 应用聚合酶链反应技术扩增血痕DNA,根据扩增产物中有无aPoB基因的数量可变重复序列(VNTR)及其扩增片段的大小即可同时确定其种属特异性和DNA的多态性。实验结果显示人血痕可见扩增带并具有多态性,而猴猪狗猫鸡血痕无扩增带。
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