Results 1 to 10 of about 11,815 (171)

Comparison between clinical evaluations and laboratory findings and the impact of biofilm on antimicrobial susceptibility in vitro in canine otitis externa

open access: yesVeterinary Dermatology, Volume 34, Issue 6, Page 586-596, December 2023., 2023
Background – In clinical practice, the diagnosis of otitis externa (OE) normally is based on otoscopic examination and cytological findings, followed by empirical treatment with topic drugs. Biofilm‐producing bacteria are frequently present in OE, even if its presence is often underdiagnosed. Hypothesis/Objectives – The primary aim of this study was to
Luca Luciani   +6 more
wiley   +1 more source

Whole genome sequencing and de novo assembly of Staphylococcus pseudintermedius: a pangenome approach to unravelling pathogenesis of canine pyoderma

open access: yesVeterinary Dermatology, Volume 32, Issue 6, Page 654-663, December 2021., 2021
Background Staphylococcus pseudintermedius is the main aetiological agent of canine pyoderma. Whole genome sequencing is the most comprehensive way of obtaining relevant genomic information about micro‐organisms. Hypothesis/Objectives Oxford Nanopore technology enables quality sequencing and de novo assembly of the whole genome of S.
Lluís Ferrer   +13 more
wiley   +1 more source

Immunopathogenesis and immunotherapy of Culicoides hypersensitivity in horses: an update

open access: yesVeterinary Dermatology, Volume 32, Issue 6, Page 579-e156, December 2021., 2021
Culicoides hypersensitivity (CH) is a strongly pruritic dermatitis of horses, characterised histologically by mixed perivascular to diffuse cellular infiltrates of mononuclear cells and eosinophils, and caused by helper T cell (Th)2, immunoglobulin (Ig)E‐mediated reactions to antigens present in the saliva of biting Culicoides midges.
Eliane Marti   +7 more
wiley   +1 more source

Prediction of the development of islet autoantibodies through integration of environmental, genetic, and metabolic markers 通过整合环境、遗传和代谢标记物预测胰岛自身抗体的发展

open access: yesJournal of Diabetes, Volume 13, Issue 2, Page 143-153, February 2021., 2021
Highlights A machine learning model can significantly predict imminent development of islet autoimmunity based on environmental, genetic, and metabolic features. The machine learning algorithm feature selection identified type 1 diabetes‐associated single nucleotide polymorphisms from The Environmental Determinants of the Diabetes in the Young (TEDDY ...
Bobbie‐Jo M. Webb‐Robertson   +10 more
wiley   +1 more source

International clinical practice recommendations on the definition, diagnosis, assessment, intervention, and psychosocial aspects of developmental coordination disorder – Chinese (Mandarin) translation

open access: yesDevelopmental Medicine &Child Neurology, Volume 61, Issue 3, Page E1-E35, March 2019., 2019
目的 本国际临床指南由欧洲残疾儿童学会(the European Academy of Childhood Disability,EACD)牵头制定,旨在解决发育性协调障碍(developmental coordination disorder,DCD)的定义、诊断、评估、干预以及与社会心理方面的临床应用关键问题。 方法 本指南针对五个领域的关键问题,通过文献综述和专家团队的正式讨论达成共识。为保证指南的循证基础,以“机制”、“评估”和“干预”为检索词, 对2012年更新以来提出的最新建议以及新增的“社会心理问题”和“青少年/成人”为检索词进行检索。根据牛津大学循证医学中心证据等级 (证据水平 [level of evidence, LOE]1–4) 将结果进行分类,最终转化为指南建议。并由国际 ...
Jing Hua   +6 more
wiley   +1 more source

A Domain‐Specific Terminology for Retinopathy of Prematurity and Its Applications in Clinical Settings

open access: yesJournal of Healthcare Engineering, Volume 2018, Issue 1, 2018., 2018
A terminology (or coding system) is a formal set of controlled vocabulary in a specific domain. With a well‐defined terminology, each concept in the target domain is assigned with a unique code, which can be identified and processed across different medical systems in an unambiguous way.
Yinsheng Zhang   +2 more
wiley   +1 more source

Monoclonal antibody against bacterial lipopolysaccharide cross-reacts with DNA-histone [PDF]

open access: yes, 1986
(1)目 的  自己抗体の産生機構を明らかにするため、リポポリサッカライド(LPS)に対する単クローン抗体と核抗原との反応性を検討した。(2)研究方法 単クローン性抗LPS抗体は、Salmonella Minnesota Re595株由来のLPSを抗原としてハイブリドーマを作製して得た。抗核抗体の検出には、ラット肝を基質として蛍光抗体法を用い、さらに二重免疫抗散法に基づき、精製核抗原との反応性を確認した。なお、抗LPS抗体は酸素免疫測定法により、LPSのエンドトキシンはリムルスを基質に用いて測定した ...
Sumazaki Ryo
core  

Robust metrics for quantifying and comparing resistance and recovery in experimental studies

open access: yesMethods in Ecology and Evolution, Volume 17, Issue 1, Page 6-14, January 2026.
Abstract Various indices have been developed to experimentally quantify resistance and recovery (two components of engineering resilience) in response to anthropogenic and natural disturbances. This diversity complicates the selection of appropriate metrics for comparing resilience across ecosystems and studies.
Zewei Zhuang   +2 more
wiley   +1 more source

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