Results 11 to 20 of about 7,014 (105)
Effect of type 2 diabetes on A disintegrin and metalloprotease 10 2型糖尿病对解整合素金属蛋白酶10表达的影响
Journal of Diabetes, Volume 14, Issue 6, Page 394-400, June 2022., 2022 Highlights a disintegrin and metalloprotease 10 (ADAM10), a sheddase responsible for the cleavage of a variety of cell surface molecules, has been implicated in the pathogenesis of Alzheimer disease, atherosclerosis, and inflammatory and neoplastic disorders, and systemic ADAM10 concentration may potentially be used as a prognostic biomarker. Our study
Sum Lam +3 more
wiley +1 more source
Journal of Diabetes, Volume 13, Issue 7, Page 562-571, July 2021., 2021 Highlights Several psychiatric disorders were associated with levothyroxine therapy (LT4). Depression, anxiety disorders, and attention‐deficit/hyperactivity disorder showed the strongest relation to LT4. Thyroid autoimmunity itself (no LT4) was not associated with psychiatric disorders.
Alexander Eckert +9 more
wiley +1 more source
Journal of Diabetes, Volume 13, Issue 2, Page 143-153, February 2021., 2021 Highlights A machine learning model can significantly predict imminent development of islet autoimmunity based on environmental, genetic, and metabolic features. The machine learning algorithm feature selection identified type 1 diabetes‐associated single nucleotide polymorphisms from The Environmental Determinants of the Diabetes in the Young (TEDDY ...
Bobbie‐Jo M. Webb‐Robertson +10 more
wiley +1 more source
Rare Metals, Volume 45, Issue 1, January 2026.ABSTRACT Nanozymes have attracted considerable attention in cancer therapy due to their adjustable enzyme activity and high catalytic efficiency. However, they still face a major challenge from tumor metastasis. In this work, endogenous/exogenous dual‐responsive bimetallic hollow PdRu (termed HPdRu) nanozymes were prepared.
Nan‐Nan Zheng, Xin Hu, Jun‐Qing Hu
wiley +1 more source
Rare Metals, Volume 45, Issue 1, January 2026.ABSTRACT The escalating issue of drug‐resistant pathogens, largely driven by the overuse of conventional antibiotics, has become a significant global health threat. Developing alternative therapeutic strategies and fabricating natural biological enzyme materials that mimic the high efficiency, selectivity, and mild‐operating conditions of natural ...
Shuai He +11 more
wiley +1 more source
Functional Ecology, Volume 39, Issue 5, Page 1274-1287, May 2025.Read the free Plain Language Summary for this article on the Journal blog. Abstract Interactions between plants and soil microorganisms in the rhizosphere are vital for maintaining the nutrient cycle and stability of terrestrial ecosystems. Nitrogen, closely related to carbon (C) cycling and ecosystem productivity, undergoes transformation by soil ...
Ru Wang +9 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2013 生物体处于不断变化的内外环境中,对环境的变化做出反应以维持生存。机体内的许多酶类和非酶类抗氧化物质通过清除代谢产生的氧自由基,使氧化和抗氧化处于平衡状态。这种平衡又随着机体应激发生改变,当氧自由基大量增加时,可导致机体组织和细胞损伤,引起多种疾病。因此,评价机体的总抗氧化状态和能力,是非常重要的。短期禁食和限制食物作为预防和治疗某些疾病的手段,逐渐受到人们的重视 ...
王文丽, 唐玉萍, 吕青, 何培霞
doaj
Effects of Ozone Water Treatments on Postharvest Quality and Physiology of Strawberry Fruit(臭氧水处理对草莓采后品质和生理的影响) [PDF]
Shipin kexue jishu xuebao, 2016 Strawberries were treated by ozone water for 3 and 9min, and effects of ozone water on postharvest quality, antioxidant compounds, and related enzymes of strawberry fruit were investigated.
LI Jian(李健) +4 more
doaj +1 more source
Zhongguo shiyan zhenduanxue, 2014 甲状腺过氧化物酶（TPO）及其抗体（TPO-Ab）所引发的免疫反应不仅引起自身免疫性甲状腺疾病,而且与其他一些疾病中有密切的关系。1甲状腺过氧化物酶（TPO）及其抗体（TPO-Ab）甲状腺过氧化物酶（TPO）是一种糖基化血红素蛋白,存在于甲状腺滤泡细胞顶端的细胞膜上,它是甲状腺激素合成的关键酶。甲状腺过氧化物酶（TPO）基因变异是甲状腺自身免疫性疾病的原因之一,在存在c等位基因的T1936C,
冯刚, 高忠, 张雅娟
doaj
Zhongguo shiyan zhenduanxue, 2016 目的观察阿特拉津（ATR）处理后小鼠心脏组织中过氧化产物的含量及Nrf2信号通路的活化,探讨ATR导致的心脏组织氧化应激损伤及保护机制。方法以玉米油溶解ATR,将32只雌性BALB/C小鼠随机分为0mg/kg、5mg/kg、25mg/kg和125mg/kg ATR剂量组,灌胃处理28d,于第29d处死小鼠取心脏组织匀浆并提取总蛋白,生化和Western blot方法检测心肌组织中过氧化产物含量、Nrf2信号通路相关蛋白的表达及抗氧化酶活性。结果ATR暴露小鼠心肌组织中NO、MDA含量增高 ...
陈俊宇 +5 more
doaj