Results 11 to 20 of about 1,173,082 (166)

草鱼肠道微生物抗生素抗性基因研究

open access: yes, 2019
水产养殖过程中抗生素的过度使用导致耐药菌株不断出现,细菌耐药性成了威胁公共安全的一个全球性问题。抗性基因是细菌产生耐药性的根本原因,动物肠道微生物是抗性基因的储存库,目前我国对水产养殖动物消化道微生物抗生素抗性基因的研究匮乏。为探究草鱼(Ctenopharyngodon idellus)肠道微生物中抗性基因的类型和丰度,通过提取草鱼肠道内容物的基因组DNA,采用shotgun宏基因组技术进行测序和序列注释,分析草鱼肠道内容物微生物数据,对比抗性基因数据库ARDB筛选出微生物序列中的抗性基因。结果表明 ...
吴山功   +4 more
core   +2 more sources

3D Printed High‐Strength Hydrogel for Dual Release of Cu2+ and Ag+ Ions to Enhance Bone Repair and Antibacterial Properties

open access: yesRare Metals, Volume 45, Issue 6, June 2026.
ABSTRACT Bone restoration is often hindered by the spatiotemporal dysregulation of immune and regenerative signals. Conventional bio‐inert implants, providing only passive support, fail to modulate this microenvironment, leading to infections and poor healing.
Zhizhong Sun   +8 more
wiley   +1 more source

Harnessing Trace Elements: Novel Radiosensitization Strategies for Enhanced Cancer Radiotherapy

open access: yesRare Metals, Volume 45, Issue 6, June 2026.
ABSTRACT Radiotherapy (RT) is one of the core methods of comprehensive cancer treatment. Globally, more than 40% of cancer patients rely on radiotherapy to achieve tumor control, cure or palliative relief. However, radiation resistance, immunosuppression and normal tissue injury limit its clinical application.
Yuhuan Zhang   +6 more
wiley   +1 more source

Ultralight N‐Doped Interconnected Porous Carbon From Lignin: Synergistic Structural and Doping Engineering for High‐Performance Electromagnetic Wave Absorption

open access: yesRare Metals, Volume 45, Issue 6, June 2026.
ABSTRACT The development of lightweight, high‐attenuation, and broadband carbon‐based electromagnetic wave absorbers is hindered by the intrinsic trade‐off between impedance matching and dielectric dissipation. Herein, we report a facile and scalable synthesis of N‐doped lignin‐derived interconnected porous carbon (Nx‐LIPC) via hydrogen‐bond self ...
Bin‐Peng Zhang   +7 more
wiley   +1 more source

Evading Strength–Ductility Trade‐Off in Titanium Matrix Composites via High‐Critical Resolved Shear Stress Dislocation Promotion and Grain Subdivision

open access: yesRare Metals, Volume 45, Issue 6, June 2026.
ABSTRACT The strength and ductility trade‐off in titanium matrix composites (TMCs) is a critical factor limiting their widespread application. In this study, a (TiB + TiC)/Ti–6Al–4V composite with an optimal balance between strength and ductility was engineered via multi‐directional forging.
Chunyu Shen   +8 more
wiley   +1 more source

Metal‐Doped Carbon‐Based Nanomaterials: Photothermal Mechanism Innovation and Precision Therapy Advancement in Antibacterial and Antitumor Applications

open access: yesRare Metals, Volume 45, Issue 5, May 2026.
ABSTRACT Metal‐doped carbon‐based nanomaterials (M‐CNM) play a strategically significant role in next‐generation precision antibacterial and antitumor therapies, as they integrate synergistic photothermal ablation, catalytic reactive oxygen species (ROS) generation, and multimodal imaging capabilities. However, their clinical translation is hindered by
Pengxiang Liu   +5 more
wiley   +1 more source

A Dual Co‐Reactant Accelerator Based On Nanoreactor‐Encapsulated CeO2 Nanozymes to Drive Potentiated Luminol Cathodic Electrochemiluminescence for Ultrasensitive Immunoassay

open access: yesRare Metals, Volume 45, Issue 5, May 2026.
ABSTRACT The precise quantification of cytokines is crucial for monitoring disease onset and progression. Herein, we developed a synergistic signal amplification approach by utilizing nanoreactor‐encapsulated CeO2 nanozymes, which were in situ electrodeposited within the mesoporous silica nanochannel film (SNF) grown on indium tin oxide (ITO ...
Yu Cui   +4 more
wiley   +1 more source

Achieving Superior Strength‐Ductility Synergy in Bionic Magnesium‐Iron Composites by Topological Optimization

open access: yesRare Metals, Volume 45, Issue 5, May 2026.
ABSTRACT Magnesium (Mg)‐based composites are regarded as promising lightweight materials with significant potential for structural applications. The structure–property relationships of bionic Mg‐based composites remain unclear. Herein, three honeycomb‐like Mg‐Fe composites are fabricated to uncover the underlying strengthening mechanisms.
Fan Zhang   +5 more
wiley   +1 more source

Simultaneous Enhancement of Strength–Ductility and Heat Resistance in Al‐Cu‐Mn Alloys Through Sn‐Mediated Precipitation and Ni/Ca‐Induced Grain‐Boundary Engineering

open access: yesRare Metals, Volume 45, Issue 5, May 2026.
ABSTRACT Giga‐casting, a near‐net‐shape manufacturing process widely used in sectors such as new energy vehicles and aerospace, demands aluminum alloys with high integration, efficiency, and comprehensive performance. However, traditional die‐cast alloys still face two core bottlenecks: the strength–ductility trade‐off and high‐temperature ...
Zhanwei Su   +3 more
wiley   +1 more source

碳青霉烯抗生素的药品不良反应1例

open access: yesZhongguo shiyan zhenduanxue, 2018
随着我国抗生素药物使用范围越发广泛,碳青霉烯抗生素被逐渐应用于各基层医院进行治疗,且使用几率逐渐增多。研究结果显示,碳青霉烯抗生素对以下几种细菌具有抗菌活性的作用:需氧菌、G+菌、G-菌及厌氧菌。随着碳青霉烯抗生素在临床上的广泛应用,其细菌耐药率不断上升,碳青霉烯抗生素的不良反应(ADRs)越发受到广大医疗人员及人们的关注[1]。碳青霉烯抗生素属于一种新型的β ...
董杨
doaj  

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