Results 21 to 30 of about 1,485,792 (153)
ABSTRACT Infected bone defects represent a dual therapeutic challenge demanding concurrent infection inhibition and osteogenesis promotion. Systemic antibiotic administration is taken as a classical treatment protocol but often yields inadequate local antibiotic concentrations and delayed bone repair.
Xucai Wang +8 more
wiley +1 more source
Metal‐Based Materials for Redox Modulation in Biomedicine
ABSTRACT Metal materials have become increasingly important in modulating biological redox networks for therapeutic and diagnostic purposes, owing to their distinctive electronic properties and adaptable reactivity. This review synthesizes recent developments across various metal‐based materials, including elemental metals, metal oxides, coordination ...
Yan Fan +7 more
wiley +1 more source
氟喹诺酮类抗生素作为喹诺酮类药物的第三代产品,已被广泛用于医疗和养殖业中。近年来,氟喹诺酮类抗生素使用量较大,在水环境中的检出频率逐年升高,对生态环境和人类健康也产生了潜在危害。对国内外氟喹诺酮类抗生素污染现状及在水中的降解进行阐述,总结了不同污水处理工艺对氟喹诺酮类抗生素的处理效果,最后展望了该领域未来的研究方向。
沙乃庆, 李艳红
doaj +2 more sources
随着我国抗生素药物使用范围越发广泛,碳青霉烯抗生素被逐渐应用于各基层医院进行治疗,且使用几率逐渐增多。研究结果显示,碳青霉烯抗生素对以下几种细菌具有抗菌活性的作用:需氧菌、G+菌、G-菌及厌氧菌。随着碳青霉烯抗生素在临床上的广泛应用,其细菌耐药率不断上升,碳青霉烯抗生素的不良反应(ADRs)越发受到广大医疗人员及人们的关注[1]。碳青霉烯抗生素属于一种新型的β ...
董杨
doaj
ABSTRACT High‐strength aluminum (Al) alloys are usually unprintable by laser powder bed fusion (LPBF) due to the severe hot cracking along the columnar grains. Doping elements scandium (Sc) and/or zirconium (Zr) is an effective way to eliminate hot cracks by refining the grain size to nearly nanoscale levels.
Zehuan Zhang +15 more
wiley +1 more source
头孢菌素是一类半合成广谱抗生素,属于B—内酰胺抗生素范畴。近年来我国随着头孢菌素类抗生素在临床的广泛应用。就用于临床的可达30—40种。在日本头孢菌素类抗生素的应用已大大超过了青霉素,成为治疗细菌感染性疾病应用最多的抗生素。发生过敏反应的病例也屡有报道。鉴于头孢类抗生素与青霉素之间有不同的交叉过敏反应,头孢菌素类过敏者均对青霉素过敏。而青霉素过敏者中约有10%对头孢菌素类也能引起过敏反应,儿童过敏反应低于成人5 ...
谢小英, 高厚发
doaj
ABSTRACT Lignin is a natural non‐toxic polyphenolic macromolecule, which shows inherent antioxidant and broad‐spectrum antibacterial activities. However, due to the low content and the high bond dissociation energy of phenolic hydroxyl groups (Ar‐O·H), its antioxidant and antibacterial activities are relatively weak, which limits its application as a ...
Meiling Han +10 more
wiley +1 more source
许多中草药有消炎、抗菌、抗病毒的作用,医药学家从这些中草药中开发出了许多抗菌药,用于抗感染治疗。这类中草药常见的有大蒜(大蒜素)、鱼腥草(鱼腥草素)、黄连(黄连素)、板蓝根(根、叶浸出物)、穿心莲(穿心莲内酯)、苦参(苦参总碱)、蒲公英(蒲公英甾醇,蒲公英素,蒲公英苦素,果胶,胆碱等)等,它们被誉为"中药抗生素"。下面我们就来聊聊其中的一味佼佼者 ...
宋松泉 +3 more
core
ABSTRACT Deep skin infections and dense biofilm barriers caused by Propionibacterium acnes (P. acnes) remain significant challenges in recurrent acne vulgaris, exacerbated by the poor stratum corneum penetration of conventional therapies and rising antibiotic resistance.
Bingran Qi +3 more
wiley +1 more source
ABSTRACT Bone restoration is often hindered by the spatiotemporal dysregulation of immune and regenerative signals. Conventional bio‐inert implants, providing only passive support, fail to modulate this microenvironment, leading to infections and poor healing.
Zhizhong Sun +8 more
wiley +1 more source

