Results 11 to 20 of about 6,100 (168)

Comparison between clinical evaluations and laboratory findings and the impact of biofilm on antimicrobial susceptibility in vitro in canine otitis externa

open access: yesVeterinary Dermatology, Volume 34, Issue 6, Page 586-596, December 2023., 2023
Background – In clinical practice, the diagnosis of otitis externa (OE) normally is based on otoscopic examination and cytological findings, followed by empirical treatment with topic drugs. Biofilm‐producing bacteria are frequently present in OE, even if its presence is often underdiagnosed. Hypothesis/Objectives – The primary aim of this study was to
Luca Luciani   +6 more
wiley   +1 more source

Trichophyton mentagrophytes complex: A retrospective study of 64 dogs from the Central United States (1997–2020)

open access: yesVeterinary Dermatology, Volume 34, Issue 4, Page 310-317, August 2023., 2023
Background – There are limited clinical studies evaluating the Trichophyton mentagrophytes complex, with most reports confined to small case studies. Additionally, the studies are dated and provide limited information on response to newer or currently available therapies.
Jason B. Pieper   +5 more
wiley   +1 more source

Bacteriophage and Fusidic Acid Have Synergistic Effect Against Meticillin‐Resistant Staphylococcus pseudintermedius in Ex Vivo Canine Dermis Model

open access: yesVeterinary Dermatology, Volume 37, Issue 2, Page 200-210, April 2026.
Background: Antimicrobial stewardship has become vital given the progressive emergence of multidrug‐resistant bacteria, and novel approaches to the treatment of bacterial infections are needed. Recently, reported synergistic effects of antibacterial drugs and bacteriophage therapy have revealed promising applications for the management of meticillin ...
Sarah Ehling   +9 more
wiley   +1 more source

Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment

open access: yesRare Metals, Volume 45, Issue 2, February 2026.
ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang   +9 more
wiley   +1 more source

NIR‐Responsive Nano‐Integrated Magnesium Phosphate Cement Promotes Bone Regeneration via Osteoblast‐Exosome‐Osteoclast Crosstalk

open access: yesRare Metals, Volume 45, Issue 2, February 2026.
ABSTRACT The limited osteogenic capacity of magnesium phosphate cement (MPC) has constrained its biomedical applications, underscoring the necessity to develop MPC with enhanced physical properties and bone‐forming capabilities. In this study, a multifunctional MPC system was developed by incorporating zoledronic acid‐loaded near‐infrared (NIR ...
Bin Wang   +8 more
wiley   +1 more source

某院临床路径前后外科抗菌药物应用分析 [PDF]

open access: yes, 2012
目的:比较临床路径前后某院外科Ⅰ类切口手术患者抗菌药物使用情况及合理性。方法:收集某院外科Ⅰ类切口手术76例实施临床路径组与88例非临床路径组病历资料,包括慢性结石性胆囊炎、股骨颈骨折、慢性硬模下血肿等3个病种,对实施临床路径前后抗菌药物应用进行统计分析。结果:外科Ⅰ类切口手术预防性抗菌药物使用率达到100%,都在术前0.5~2 h内进行预防性给药,手术时间在3 h内,术中都无追加抗菌药物。实施临床路径的病例,抗菌药物平均术后停药时间有所缩短,第1、2代头孢菌素类抗菌药物使用比例上升 ...
林嘉民, 黄南春
core  

Changes in Knowledge and Attitudes towards Antibiotic Use among Primary Care Physicians in Hubei Province:a Propensity Score-matched Analysis [PDF]

open access: yes, 2022
BackgroundPhysicians' irrational antibiotic prescriptions are fueling antibiotic resistance and seriously threatening public health. Physicians' knowledge and attitudes towards antibiotic use will directly affect their behaviors.ObjectiveTo ...
DUAN Lixia, LIU Chenxi
core   +1 more source

Single Cold Atmospheric Plasma Therapy May Improve the Treatment Outcome of Canine Otitis Externa With Secondary Infection

open access: yesVeterinary Dermatology, Volume 37, Issue 1, Page 103-110, February 2026.
Background: Otitis externa with secondary bacterial or yeast infection is a common problem in small animal practice. Cold physical plasma (CPP) has been reported to have antimicrobial activity in vitro. Results: Ears treated additionally with CPP showed lower otic scores after 21 days compared to nontreated ears, although this difference was not ...
Ralf S. Mueller, Cosima Bouassiba
wiley   +1 more source

883例术中抗菌药物使用情况调查分析 [PDF]

open access: yes, 2015
不定期地进入医院手术室,抽取在台手术病历,填写患者的基本信息及用药调查表。输入EXCEl表,进行统计分析并院内通报。在883份病历中,抗菌药物的使用率:62.51%(552/883),治疗性使用抗菌药物30例,预防性使用抗菌药物522例,联合用药5例。应用抗菌药物种类以头孢类为主,达460例次(88.12%)。抗菌药物使用合理率:81.31%(718/883)。说明我院手中抗菌药物使用基本合理,但存在预防用药使用率偏高、选药不当等不足 ...
于阗, 陈华漫
core  

Multi‐Scale Rational Design and Synergistic Strategies of Nanozymes for Targeting Drug‐Resistant Pathogens

open access: yesRare Metals, Volume 45, Issue 1, January 2026.
ABSTRACT The escalating issue of drug‐resistant pathogens, largely driven by the overuse of conventional antibiotics, has become a significant global health threat. Developing alternative therapeutic strategies and fabricating natural biological enzyme materials that mimic the high efficiency, selectivity, and mild‐operating conditions of natural ...
Shuai He   +11 more
wiley   +1 more source

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