Results 11 to 20 of about 644,852 (165)
Zhongshan Daxue xuebao. Yixue kexue ban, 2010 【目的】 探讨红霉素65380;环丙沙星65380;左氧氟沙星65380;莫西沙星4种抗菌药物对细胞内嗜肺军团菌的抗菌活性65377;【方法】 分别采用E-test法和有限稀释法测定上述4种药物对嗜肺军团菌ATCC 33152的细胞外抗菌活性,再用噻唑蓝比色法(MTT法)测定上述药物对嗜肺军团菌ATCC 33152的细胞内抗菌活性65377;【结果】 细胞外抗菌活性E-test法:红霉素0.047 μg/mL65380;环丙沙星0.38 μg/mL65380;左氧氟沙星0.125 μg/mL65380 ...
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Zhongshan Daxue xuebao. Yixue kexue ban, 1999 目的: 探讨不同类型的抗菌药物释放细菌内毒素潜能和速率的不同。方法: 选择 5 种不同类型抗菌药物单独或 联合作用于大肠杆菌,比较 4 h 期间游离内毒素, 同时作菌落计数和细菌形态学检查。结果: 亚胺培南-西司他丁杀菌作用和 释放内毒素最快,但释放内毒素量较少; 头孢他啶释放内毒素较快,量较多; 环丙沙星释放缓慢, 量中等; 阿米卡星释放缓慢, 量最小; 头孢曲松致细菌丝状体形成, 杀菌并释放内毒素最慢但量最大; 阿米卡星和头孢曲松联合用药有协同抗菌作用, 且明 显减少头孢曲松释放内毒素的量 ...
吴朝晖 张扣兴 唐英春
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Veterinary Dermatology, Volume 34, Issue 6, Page 586-596, December 2023., 2023 Background – In clinical practice, the diagnosis of otitis externa (OE) normally is based on otoscopic examination and cytological findings, followed by empirical treatment with topic drugs. Biofilm‐producing bacteria are frequently present in OE, even if its presence is often underdiagnosed. Hypothesis/Objectives – The primary aim of this study was to
Luca Luciani +6 more
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, 2002 目前 ,抗菌药物在水产养殖动物疾病防治中占有重要地位 ,然而 ,在水产养殖中使用抗菌药物也可产生一系列的副作用 ,例如细菌耐药性的产生和药物在鱼体和环境中的残留。本文就水产药物使用的历史、现状、适应症、副作用 ,耐药性的现状、来源、产生机制 ,耐药菌判定的标准 ,以及该领域的研究现状等问题进行综述与分析 ...
李爱华
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Rare Metals, Volume 45, Issue 4, April 2026.ABSTRACT Diabetic wound infections are a common complication of diabetes, which severely impact patients' quality of life. Effective treatment of diabetic wound infections remains one major challenge in the clinic, partially due to the formation of bacterial biofilm and antibiotic resistance.
Liang Zhou +8 more
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Veterinary Dermatology, Volume 37, Issue 2, Page 200-210, April 2026.Background: Antimicrobial stewardship has become vital given the progressive emergence of multidrug‐resistant bacteria, and novel approaches to the treatment of bacterial infections are needed. Recently, reported synergistic effects of antibacterial drugs and bacteriophage therapy have revealed promising applications for the management of meticillin ...
Sarah Ehling +9 more
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Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment
Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang +9 more
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Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT The limited osteogenic capacity of magnesium phosphate cement (MPC) has constrained its biomedical applications, underscoring the necessity to develop MPC with enhanced physical properties and bone‐forming capabilities. In this study, a multifunctional MPC system was developed by incorporating zoledronic acid‐loaded near‐infrared (NIR ...
Bin Wang +8 more
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Veterinary Dermatology, Volume 37, Issue 1, Page 103-110, February 2026.Background: Otitis externa with secondary bacterial or yeast infection is a common problem in small animal practice. Cold physical plasma (CPP) has been reported to have antimicrobial activity in vitro. Results: Ears treated additionally with CPP showed lower otic scores after 21 days compared to nontreated ears, although this difference was not ...
Ralf S. Mueller, Cosima Bouassiba
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Rare Metals, Volume 45, Issue 1, January 2026.ABSTRACT The escalating issue of drug‐resistant pathogens, largely driven by the overuse of conventional antibiotics, has become a significant global health threat. Developing alternative therapeutic strategies and fabricating natural biological enzyme materials that mimic the high efficiency, selectivity, and mild‐operating conditions of natural ...
Shuai He +11 more
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