【目的】 探讨脾细胞输注致敏对异基因供者骨髓细胞损伤的作用机制65377;【方法】 应用异基因脾细胞输注的BALB/c小鼠作为致敏模型,未致敏(正常)BALB/c小鼠作为对照,异基因供者骨髓细胞来源于C57BL/6小鼠65377;通过补体依赖细胞毒性反应(CDC)65380;细胞毒性免疫细胞杀伤作用65380;抗体依赖细胞介导的细胞毒性作用(ADCC)65380;粒-单核细胞集落培养(CFU-GM)等实验研究致敏血清及致敏免疫细胞对异基因骨髓细胞的影响65377;【结果】 与补体孵育30 min或1 ...
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