枸杞多糖(lycium barbarum polysaccharides,LBP)作为枸杞子的主要活性成分已日益得到临床医生的高度重视。研究表明,LBP有增强机体的免疫功能和显著的抗肿瘤效应,它能从调动机体自身的抗病能力出发,在提高机体免疫力的同时杀伤肿瘤细胞[1];它能促进骨髓有核细胞数和粒/巨噬细胞集落数量的增加(CFU-GM ...
杨书良 +3 more
doaj
Lyciumbarbarum polysaccharides ameliorate canine acute liver injury by reducing oxidative stress, protecting mitochondrial function, and regulating metabolic pathways. [PDF]
Huang J +8 more
europepmc +1 more source
枸杞多糖通过激活Nrf2/HO-1通路保护HK-2细胞氧化损伤的作用
目的 分析枸杞多糖(LBP)干预对氧化损伤的人肾小管上皮细胞(HK-2)内的核因子E2相关因子2(Nrf2)/血红素氧合酶-1(HO-1)通路蛋白表达的变化,探索LBP拮抗HK-2细胞氧化损伤的分子机制。方法 采用过氧化氢诱导HK-2细胞制备氧化损伤细胞模型,HK-2被分成4组:正常组、LBP组、氧化损伤组及LBP干预组。观察4组细胞的长势和形态变化;细胞活力测定法比较每组细胞的存活率;比色法分析氧化产物丙二醛(malondialdehyde, MDA)含量以及超氧化物歧化酶(superoxide ...
赵杰 +6 more
doaj
Medication rule of traditional Chinese medicine in the treatment of plateau hypoxia based on data mining. [PDF]
Wang R +6 more
europepmc +1 more source
[Exploring the therapeutic mechanism of Longqi Fang for diabetic kidney disease based on network pharmacology and verification in rats]. [PDF]
Xing L, Xing W, Guo H.
europepmc +1 more source
枸杞多糖通过激活Nrf2/HO-1通路保护HK-2细胞氧化损伤的作用 附视频
目的 分析枸杞多糖(LBP)干预对氧化损伤的人肾小管上皮细胞(HK-2)内的核因子E2相关因子2(Nrf2)/血红素氧合酶-1(HO-1)通路蛋白表达的变化,探索LBP拮抗HK-2细胞氧化损伤的分子机制。方法 采用过氧化氢诱导HK-2细胞制备氧化损伤细胞模型,HK-2被分成4组:正常组、LBP组、氧化损伤组及LBP干预组。观察4组细胞的长势和形态变化;细胞活力测定法比较每组细胞的存活率;比色法分析氧化产物丙二醛(malondialdehyde, MDA)含量以及超氧化物歧化酶(superoxide ...
doaj +2 more sources
Exercise performance reduction and preventive measures in highland sports. [PDF]
Li B +5 more
europepmc +1 more source
[Determination of 118 pesticide residues in dried wolfberry by gas chromatography-triple quadrupole mass spectrometry in dynamic multiple reaction monitoring mode]. [PDF]
Yang Z, Zhang W, Wu F, Wang X, Xu X.
europepmc +1 more source
[Exploration of the therapeutic mechanism of Yiqi Jiedu recipe for treatment of primary liver cancer based on network pharmacology and molecular docking]. [PDF]
Xu M, Zhang P, Zhang G.
europepmc +1 more source
[Zuogui Jiangtang Jieyu Decoction promotes neural stem cell self-renewal and activates Shh signaling in the hippocampal dentate gyrus of diabetic rats with depression]. [PDF]
Yang H +9 more
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