[Veratric acid relieves oxidative stress and DSS-induced colitis in mice by activating the Nrf2/HO-1 signaling pathway]. [PDF]
Yin L +8 more
europepmc +1 more source
[Isovitexin alleviates myocardial oxidative stress injury in diabetic mice by enhancing myocardial SIRT3 expression and reducing oxidative stress]. [PDF]
Peng Y +6 more
europepmc +1 more source
目的 通过检测补锌对高脂饮食诱导的糖调节受损(IGR)大鼠肝脏病理变化、氧化和抗氧化、线粒体损伤及凋亡的影响,探讨补锌缓解IGR肝脏损伤的机制。方法 雄性Wistar大鼠80只,利用长程高脂饮食连续喂养20周建立IGR模型,并利用苏木素-伊红(HE)染色检测胰腺的病理损伤。32只IGR模型大鼠随机分成IGR模型组(IGR)、15 mg·kg-1·d-1补锌组(IGR+Zn15mg)、30 mg·kg-1·d-1补锌组(IGR+Zn30mg)和二甲双胍阳性药物组(IGR+Met)组,每组8只 ...
王琳, 方芳, 田宏远, 吕巍
doaj
[Application of Kartogenin in cartilage tissue engineering]. [PDF]
Jiang J, Zhang S, Lu W.
europepmc +1 more source
摘 要: 【目的】 探讨利福平对鱼藤酮诱导的BV2小胶质细胞氧化损伤中的核因子E2相关因子2(Nrf2)信号通路的影响?【方法】 利用鱼藤酮刺激的BV2小胶质细胞建立帕金森病氧化应激的模型,分别用不同浓度的利福平预处理BV2小胶质细胞,CCK-8法检测细胞存活率;分别用双氯荧光素(DCFH-DA)?罗丹明123染色后使用流式细胞仪检测活性氧(ROS)水平和线粒体膜电位(MMP);使用脂质氧化检测试剂盒测定细胞内脂质过氧化终产物丙二醛( MDA) 的含量?采用Western ...
doaj
[Total Astragalus saponins reduce astrocyte swelling and AQP4 expression following oxygen-glucose deprivation and reoxygenation by inhibiting the p38 pathway]. [PDF]
Yin Q, Lei Y, Wang X, Yang G, Tang Z.
europepmc +1 more source
Trx2、GSH和GSH-PX与大鼠肝移植术后肾损伤修复的相关性研究
【目的】 探讨线粒体型硫氧还蛋白(Trx2),谷胱甘肽(GSH)和谷胱甘肽过氧化物酶(GSH-PX)对肝移植术后急性肾损伤的保护作用。【方法】 建立大鼠肝移植模型,将雄性SD大鼠35只,随机均分为假手术组(n = 7)和移植后4 h组(n = 7),移植后8 h组(n = 7),移植后16 h组(n = 7)和移植后24 h组(n = 7)。假手术组只进行开腹和血管的分离,各移植组接受自体肝移植。观察大鼠自体肝移植后不同时期肾脏病理、活性氧水平、Trx2表达、乳酸脱氢酶(LDH)、谷胱甘肽(GSH ...
doaj
[Medical treatment standards for emergency burn wounded (2025 edition)]. [PDF]
National Health Commission Of The People's Republic Of China.
europepmc +1 more source
[Application of chromatography-mass spectrometry in the clinical analysis of multiple sclerosis]. [PDF]
Yao ZY +5 more
europepmc +1 more source
[Medical treatment standards for emergency trauma wounded (2025 edition)]. [PDF]
National Health Commission Of The People's Republic Of China.
europepmc +1 more source

