Results 31 to 40 of about 7,342 (145)
Preparation and Characterization of Antioxidant Peptides from Pumpkin Seeds and Their Protective Effect against H2O2-induced Damage in Caco-2 Cells [PDF]
In this study, antioxidant peptides were prepared from defatted pumpkin seeds and purified by ultrafiltration and reverse-phase high performance liquid chromatography (RP-HPLC).
HAN Xunze, YU Wenjun, ZHANG Yu, ZHAO Jing, LI Quanhong
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Zhongguo shiyan zhenduanxue, 2007 目的探讨急性肾缺血再灌注损伤过程氧化侵袭与肾细胞凋亡在肾损伤发生机制中的作用。方法采用摘除大鼠左肾,钳夹右侧肾蒂的方法,制成急性缺血再灌注肾损伤模型,测定GSH-Px、SOD活性和MDA含量及检测肾细胞凋亡率。结果缺血再灌注不同时期肾组织SOD活力水平降低,与对照组相比差异显著 ...
周高标, 徐淑艳, 王伟刚, 洪泉
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Hericium erinaceus Compound Beverage and Its Ameliorative Effect on Alcohol-induced Oxidative Injury in Rats [PDF]
Objective: To develop a Hericium erinaceus beverage and investigate its protective effect on alcohol-induced gastric mucosa injury in vivo. The antioxidant properties were possessed by H. erinaceus, and the gastrointestinal tract was protected.
Chenglin WU +8 more
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Optimization of the Best Polar Site for Antioxidant Activity of Panax ginseng Extract Based on Entropy Weight Method and Grey Relational Analysis Combined with Component Analysis [PDF]
Objective: The differences in antioxidant activity of different polar parts of panax ginseng were investigated to screen the best active parts. Method: In this study, the water extract of Panax ginseng was extracted by petroleum ether, chloroform, ethyl ...
Fengqin XIAO +7 more
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小柴胡汤对过氧化氢诱导的人皮肤成纤维细胞氧化应激损伤的保护作用
Zhongguo shiyan zhenduanxue, 2018 目的研究小柴胡汤水煎液对过氧化氢诱导的人皮肤成纤维细胞氧化应激损伤的保护作用。方法培养人皮肤成纤维细胞（HDF）,建立HDF细胞H2O2损伤模型;使用不同浓度（20、50、100μg/ml）小柴胡汤水煎液干预H2O2损伤的HDF细胞,并设置H2O2模型组;MTT法检测细胞活力;化学发光法检测细胞内丙二醛（MDA）、超氧化物歧化酶（SOD）及活性氧（ROS）含量,蛋白质印迹法检测Bcl-2、Bax、NF-kB和p53蛋白表达。结果相对于H2O2模型组,20、50、100μg ...
王春宇, 姜民, 侯冠宇, 侯吉光
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Effect of Ligilactobacillus salivarius M18-6 on Flavor Quality and Antioxidant Activity of Fermented Soymilk [PDF]
In this study, the effect of Ligilactobacillus salivarius M18-6, with the capability to stably and rapidly ferment soybean protein and strong antioxidant capacity, on the flavor quality and antioxidant activity of fermented soymilk was analyzed.
DENG Yu, JIA Yu, NIU Junxia, WANG Yulan, XIE Yuanhong, ZHANG Hongxing, SONG Xiaodong, CHENG Congyang, GE Shaoyang, JIN Junhua
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Zhongguo shiyan zhenduanxue, 2007 目的通过UVB照射导致的角朊细胞中丙二醛（MDA）、羟自由基（OH.）和超氧阴离子（O2-）水平的改变和清除这些物质酶类含量和活性的改变,探讨B段紫外线对角朊细胞的损伤作用及机制。方法实验组的角朊细胞用UVB进行照射,对照组细胞用普通日光灯照射。分别测定并比较实验组和对照组细胞产生MDA、OH.和O2-的水平以及两组之间谷胱甘肽过氧化物酶、超氧化物歧化酶的改变,探讨UVB导致角朊细胞的损伤作用及机制。结果实验组角朊细胞产生的MDA、OH.和O2-的水平显著高于对照组 ...
李云 +5 more
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Zhongguo shiyan zhenduanxue, 2012 目的研究微小RNA（microRNA,简称miRNA）与心肌细胞氧化应激的关系,作为探讨缺血再灌注损伤分子病理生理的基础。方法培养中的H9c2（2-1）心肌细胞以过氧化氢处理产生氧化应激,然后收集心肌细胞提取miRNA。选取miR-210和miR-24进行逆转录,再进行定量实时聚合酶链式反应。结果心肌细胞以过氧化氢处理2h后,与对照相比,miR-210显著降低至对照水平的47.07%（P=0.013）,而miR-24的水平则大幅升高,达到了对照水平的344.48%（P=0.002）。结论 ...
郭威早, 张显峰, 纪红
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Zhongguo youzhi旨在为紫苏饼粕的高值化利用提供参考，以采用水提醇沉法从紫苏粕中提取的紫苏多糖（PMP）为原料，检测其对羟自由基（·OH）、超氧阴离子自由基（O-2·）、1，1-二苯基-2-三硝基苯肼自由基（DPPH·）和亚硝酸盐（NO-2）的清除能力，考察其体外抗氧化活性；同时，使用H2O2建立LO2细胞氧化损伤模型，在细胞水平上探讨PMP的抗氧化能力，并进一步研究PMP对LO2肝细胞氧化应激损伤的保护作用机制。结果表明：PMP对·OH、O-2·、DPPH·、NO-2均具有一定的清除能力，其EC50分别为964.59 ...
王士博，孔令雪，刘金娟 WANG Shibo, KONG Lingxue, LIU Jinjuan
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Zhongguo shiyan zhenduanxue, 2009 目的研究雷米普利对大鼠心肌缺血再灌注损伤的影响,并初步探讨其作用机制。方法大鼠在体结扎冠状动脉前降支30 min后,松扎再灌注120 min制备心肌缺血再灌注损伤模型,计算心肌梗死范围（MIS）,测定血清天门冬氨酸氨基转换酶（AST）、磷酸肌酸激酶（CK）、乳酸脱氢酶（LDH）、超氧物歧化酶（SOD）、谷胱甘肽过氧化物酶（GSH-Px）活性及丙二醛（MDA）、一氧化氮（NO）含量,血浆内皮素（ET）、血管紧张素Ⅱ（AngⅡ）、前列环素（PGI2）及血栓素A2（TXA2）水平。结果雷米普利对心肌缺血30 ...
于倩 +5 more
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