Results 41 to 50 of about 6,409 (145)
Zhongshan Daxue xuebao. Yixue kexue ban, 2021 目的过度氧化应激可促进血小板氧化损伤，从而加快心血管疾病的发生发展。水溶性番茄浓缩物（Fruitflow）具有抑制血小板聚集、活化的作用，但是否通过自噬减轻血小板氧化损伤仍未见报道。本研究拟通过体外实验探讨Fruitflow对过氧化氢（H2O2）导致的血小板氧化损伤的影响及其潜在机制。方法用不同剂量的Fruitflow （0、20、40、80 mg/L）与纯化血小板预孵育30 min，随后加入H2O2共孵育60 min。用流式细胞术测定线粒体膜电位（ΔΨm）去极化的水平；用酶标仪测定活性氧（ROS ...
李孔耀 +7 more
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野生动物学报, 2013 目的:研究熊胆粉对乙醇诱导的小鼠肝细胞氧化损伤的保护作用。方法:Ⅰ型、Ⅳ型胶原酶和DNA酶联合消化分离、培养小鼠原代肝细胞,乙醇诱导小鼠肝细胞损伤,MTT法检测肝细胞存活率,不同浓度熊胆粉预处理肝细胞,观察培养液中丙二醛（MDA）、还原型谷胱甘肽（GSH）含量和超氧化物歧化酶（SOD）活性。结果:乙醇对肝细胞的损伤呈量效关系,与正常对照组相比,损伤组培养液中MDA含量明显增加,GSH含量显著降低 ...
刘菁菁, 肖向红, 薛艺, 柴龙会
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Amelioration of oxidative kidney damage in offspring by maternal trans-fatty acid exposure in mice by secoisolariciresinol diglucoside. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2023 Chen M, Zhu R, Wu T, Zhao W.
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DNA oxidative damage induced by natural pyrethrins in human liver cells [PDF]
BackgroundNatural pyrethrins have long been widely used in the fields of environmental and household hygiene. Studies have reported that natural pyrethrins have potential liver toxicity, but their specific mechanisms are still unclear yet.
Gonghua TAO +6 more
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Zhongguo shiyan zhenduanxue, 2005 目的 探讨Aβ2 5-3 5致PC12细胞损伤后线粒体COX活性和ATP合成的改变及人参皂甙对它们的影响。方法 Aβ2 5-3 5损伤PC12细胞 ,人参皂甙处理前后紫外分光光度计测定线粒体COX活性 ,高效液相色谱仪测定线粒体能荷。结果 Aβ2 5-3 5损伤PC12细胞后 ,线粒体COX活性降低 ,线粒体ATP、ADP含量降低 ,人参皂甙能提高线粒体COX活性及ATP、ADP含量。结论 人参皂甙通过抗氧化作用可以减轻Aβ2 5-3 5致PC12细胞线粒体的氧化损伤。
赵丽波, 张琳, 邬英全, 周维国
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Zhongguo shiyan zhenduanxue, 2022 目的 观察竹节参总皂苷对大鼠心肌缺血再灌注损伤的影响及机制。方法 将雄性Wistar大鼠随机分为5组:假手术组、模型组、地奥心血康组50.0mg·kg-1、竹节参总皂苷50.0mg·kg-1组及100.0mg·kg-1组。结扎大鼠心脏冠状动脉左前降支(LDA)30min再灌注120min,制备心肌缺血再灌注损伤模型,取血及心肌组织。利用生物试剂盒检测血清中天门冬酸氨基转移酶(AST)、乳酸脱氢酶(LDH)、丙二醛(MDA)、超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)的含量 ...
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Polysaccharide isolated from wax apple suppresses ethyl carbamate-induced oxidative damage in human hepatocytes. [PDF]
J Zhejiang Univ Sci B, 2023 Bao T +4 more
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Research EA stomach meridian stress ulcer inhibition mechanism of oxidative damage [PDF]
, 2015 目的：观察电针胃经“梁门”、“足三里”穴对应激性胃溃疡大鼠胃黏膜损伤的修复作用，利用组织形态学和酶联免疫等分子生物学方法检测应激性胃溃疡大鼠胃黏膜组织氧化损伤相关因子的表达，从分子水平探讨电针促进应激性胃溃疡大鼠胃黏膜保护的作用机制，为针灸防治胃黏膜损伤疾病提供科学实验依据。 方法：40只SD大鼠随机分为4组：正常组、模型组、胃经穴组、胆经穴组。采用束缚-冷应激（WRS）法制作应激性胃溃疡大鼠模型。造模后次日起，胃经穴组每天电针梁门、足三里30分钟，连续7天，左右交替进行；胆经穴组每天电针胆经日月 ...
RENNY OCTAVIANI
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[Mechanisms mediating the inhibitory effects of quercetin against phthalates-induced testicular oxidative damage in rats]. [PDF]
Nan Fang Yi Ke Da Xue Xue Bao, 2023 Liu L +5 more
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Structural Characterization and Antioxidant Activity of Walnut Peptides [PDF]
This study prepared and structurally characterized peptides with different molecular masses from walnut meal protein by enzymatic hydrolysis with a mixture of two proteases followed by ultrafiltration, and it also explored the antioxidant activities of ...
ZHANG Zijie, TIAN Yiling, XIA Junxia, MA Aijin
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