Zhongshan Daxue xuebao. Yixue kexue ban, 2009 【目的】 研究化妆品添加剂-氧化锌纳米粒子对正常人胚肺成纤维细胞(HELF)的生物毒性65377; 【方法】 采用MTT法检测氧化锌纳米粒子对体细胞存活率的影响;利用光学显微镜评价细胞的形态学变化;电子显微镜观察细胞与纳米氧化锌作用前后表面微结构的变化65377; 【结果】 在测试的2.5 ~ 150 mg8226;L-1浓度范围内,氧化锌纳米粒子对HELF细胞均有抑制作用, 细胞毒性呈明显的剂量依赖效应关系65377;浓度在20 mg8226;L-1以上时,氧化锌纳米粒子可致使细胞生存率低于10 ...
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