Results 41 to 50 of about 4,985 (88)

[A case report of Diets-Jongmans syndrome caused by a <i>KDM3B</i> gene variant]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Shen KX, Xiang YJ, Wang J, Ren KY, Ding Y.   +4 more
europepmc   +1 more source

赖氨酸琥珀酰化修饰的病理生理学功能及分子机制的研究进展

Zhongguo shiyan zhenduanxue
近年来，蛋白质翻译后修饰的研究成为生物医学领域的热点之一。其中，赖氨酸的琥珀酰化修饰是一种由小分子代谢物琥珀酰-辅酶A（succinyl-CoA）介导的赖氨酸残基的酰基化修饰，能够影响蛋白质的结构与功能。这种修饰既可以发生在组蛋白，也可以发生在非组蛋白（如线粒体蛋白）的赖氨酸基团。该修饰过程与细胞代谢状态紧密相关，在多种生理及病理过程中发挥重要作用，其调控下游靶基因蛋白质的功能和参与疾病进程中的作用也逐渐受到关注。本文旨在综述琥珀酰化修饰在疾病中的作用及其潜在的分子机制 ...
王铭瑧, 姜婷婷, 听夏, 司文喆
doaj  

[Gut-brain-joint axis in rheumatoid arthritis: from microeco-logical disturbance to multi-target synergy]. [PDF]

Zhejiang Da Xue Xue Bao Yi Xue Ban
Yi S, He Q, Li Y, Wan B.
europepmc   +1 more source

[<i>Zhizichi</i> Decoction alleviates depression-like behaviors in rats exposed to chronic unpredictable mild stress by modulating tryptophan metabolism and the BDNF signaling pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Meng T, Qin M, Xia Y.
europepmc   +1 more source

[Exogenous nitric oxide suppresses K _ATP channel activity through S-nitrosylation]. [PDF]

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi
Wang X, Zhang Y, Hu W, Hao X.
europepmc   +1 more source

[Research progress on the multidimensional regulation of gut microbiota on metabolism, immunity, and inflammatory response in metabolic associated fatty liver disease]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Wu ST, Lu XL.
europepmc   +1 more source

[Growth differentiation factor 11 attenuates hypoxia/reoxygenation injury in rat H9C2 cardiomyocytes <i>in vitro</i> by inhibiting thioredoxin-1 nitrative inactivation]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Wei J, Jiang W, Xia L, Lü L, Yang Q.
europepmc   +1 more source

[Research progress on the quercetin target role and signaling pathway in anti-liver fibrosis]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Zhao RQ, Liu HY, Yan JM, Hao Y, Ding YX, Zhang F, Zhou RM, Zhao R, Bai F, Bai WF.   +9 more
europepmc   +1 more source

[Research Progress on the Role and Mechanisms of PYCR1 
in Tumorigenesis and Progression]. [PDF]

Zhongguo Fei Ai Za Zhi
Meng Y, Yang Z, Feng H, Li H, Li B.
europepmc   +1 more source

[Clinical study on the efficacy of Wuling capsules combined with nucleos(t)ide analogues in the treatment of low-level viremia patients with chronic hepatitis B]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Zhao SX, Ren WG, Yang MB, Chi XL, Xiao HM, Ma SP, Jia P, Nan YM.   +7 more
europepmc   +1 more source