Results 21 to 30 of about 3,852,262 (100)
RNA Biology, 2020 Ebola virus (EBOV) RNA has the potential to form hairpin structures at the transcription start sequence (TSS) and reinitiation sites of internal genes, both on the genomic and antigenomic/mRNA level.
Simone Bach +4 more
semanticscholar +1 more source
Genome sequencing in microfabricated high-density picolitre reactors
Nature, 2005 The proliferation of large-scale DNA-sequencing projects in recent years has driven a search for alternative methods to reduce time and cost. Here we describe a scalable, highly parallel sequencing system with raw throughput significantly greater than ...
M. Margulies +55 more
semanticscholar +1 more source
The life of U6 small nuclear RNA, from cradle to grave
RNA: A publication of the RNA Society, 2018 Removal of introns from precursor messenger RNA (pre-mRNA) and some noncoding transcripts is an essential step in eukaryotic gene expression.
A. Didychuk, S. Butcher, D. Brow
semanticscholar +1 more source
Nature Cell Biology, 2008 Glioblastoma tumour cells release microvesicles (exosomes) containing mRNA, miRNA and angiogenic proteins. These microvesicles are taken up by normal host cells, such as brain microvascular endothelial cells.
J. Skog +9 more
semanticscholar +1 more source
Ancestry patterns inferred from massive RNA-seq data
RNA: A publication of the RNA Society, 2019 There is a growing body of evidence suggesting that patterns of gene expression vary within and between human populations. However, the impact of this variation in human diseases has been poorly explored, in part owing to the lack of a standardized ...
R. Barral-Arca +4 more
semanticscholar +1 more source
Drug treatment options for the 2019-new coronavirus (2019-nCoV).
BioScience Trends, 2020 As of January 22, 2020, a total of 571 cases of the 2019-new coronavirus (2019-nCoV) have been reported in 25 provinces (districts and cities) in China.
Hongzhou Lu
semanticscholar +1 more source
Real-time quantification of microRNAs by stem–loop RT–PCR
Nucleic Acids Research, 2005 A novel microRNA (miRNA) quantification method has been developed using stem–loop RT followed by TaqMan PCR analysis. Stem–loop RT primers are better than conventional ones in terms of RT efficiency and specificity.
Caifu Chen +12 more
semanticscholar +1 more source
Assessment of transcript reconstruction methods for RNA-seq
Nature Methods, 2013 We evaluated 25 protocol variants of 14 independent computational methods for exon identification, transcript reconstruction and expression-level quantification from RNA-seq data.
Tamara Steijger +7 more
semanticscholar +1 more source
Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity
Nature, 2013 The type I interferon (IFN) response protects cells from viral infection by inducing hundreds of interferon-stimulated genes (ISGs), some of which encode direct antiviral effectors.
J. Schoggins +21 more
semanticscholar +1 more source
Genes & Development, 2005 Dicer is the enzyme that cleaves double-stranded RNA (dsRNA) into 21-25-nt-long species responsible for sequence-specific RNA-induced gene silencing at the transcriptional, post-transcriptional, or translational level.
C. Kanellopoulou +7 more
semanticscholar +1 more source