Results 1 to 10 of about 3,304 (160)

Characteristic changes in blood routine and peripheral blood lymphocyte subpopulations in recipients of different types of rejection. [PDF]

open access: yesZhong Nan Da Xue Xue Bao Yi Xue Ban
目的 排斥反应一直是限制移植肾存活的最重要因素。移植肾病理活检是排斥反应诊断的金标准,但因其局限性并不能作为常规监测手段。近来,外周血淋巴细胞亚群检测已成为评估机体免疫系统的重要手段,然而其在肾移植领域的应用价值和策略有待探究;此外,常规检验参数的新开发利用也是探索肾移植疾病诊断策略和预测模型的重要手段。本研究旨在结合血常规,探究外周血淋巴细胞亚群与T细胞介导的排斥反应(T cell-mediated rejection,TCMR)和抗体介导的排斥反应(antibody-mediated ...
Luo S   +9 more
europepmc   +2 more sources

[Expression and diagnostic value of lymphocyte subsets and activation status in non-Hodgkin's lymphoma-associated hemophagocytic lymphohistiocytosis]. [PDF]

open access: yesZhonghua Xue Ye Xue Za Zhi
目的 探讨外周血淋巴细胞和功能活化状态在非霍奇金淋巴瘤相关噬血细胞综合征(NHL-HLH)中的表达和诊断价值。 方法 回顾性分析江苏省人民医院2022年9月至2023年9月收治的30例初诊NHL-HLH患者的临床资料,流式细胞术检测淋巴细胞亚群和功能活化指标。选取同期在本院接受治疗的40例初诊NHL且完善淋巴细胞和功能活化指标的患者作为对照组。比较两组淋巴细胞计数和活化指标的差异。运用受试者工作特征曲线和Logistic回归分析识别NHL-HLH的风险因素。 结果 NHL-HLH组中,T细胞淋巴瘤12例,
Yin GL   +8 more
europepmc   +2 more sources

Comparison of the effects between traditional open surgery and laser treatment combined with foam sclerotherapy on immune system in patients with primary great saphenous varicose veins [PDF]

open access: yes, 2023
Objective To compare the effects of traditional open surgery and laser therapy combined with foam sclerotherapy on immune system in patients with primary saphenous varicose veins.
He Chuan, Ding Yang, Gu Junfei, Wan Shengyun
core   +1 more source

EZH1/2抑制剂UNC1999对外周血免疫细胞表型的影响 [PDF]

open access: yes, 2021
目的探讨EZH1/2抑制剂UNC1999对外周血免疫细胞表型的影响。方法用CCK-8法检测UNC1999作用于外周血单个核细胞(PBMC)后的细胞存活率;多色流式细胞术分析免疫细胞表型。结果相比对照组,UNC1999组经典型单核细胞(CD14++CD16-)比例上调[(19.53±1.79)% vs. (66.60±5.02)%,t=13.31,P=0.006],中间型单核细胞(CD14++CD16+)和非经典型单核细胞(CD14+CD16+)比例下调[(35.08±3.97)% vs.
刘丹平   +4 more
core   +1 more source

Research on T Lymphocyte Subsets and NK Cells Activity in Peripheral Blood of Hypopharyngeal Squamous Cell Carcinoma [PDF]

open access: yes, 2017
目的:分析下咽鳞状细胞癌患者外周血T淋巴细胞亚群和NK细胞活性情况,旨在为相关研究工作提供参考资料。方法:择取2011年6月-2016年5月本院收治的95例下咽鳞状细胞癌病患为病例组,另取此期间内来本院接受健康检查的72例志愿者为正常组。使用流式细胞仪对病患开展相关检查,分析病例组与正常组的淋巴细胞亚群、NK活性情况以及不同临床分期的下咽癌病患外周血T淋巴细胞亚群以及NK细胞活性之间的关系。结果:与正常组相比,病例组的NK细胞、总B淋巴细胞、总T淋巴细胞、辅助/抑制T细胞、辅助T细胞偏低(P0.05 ...
刘存山   +7 more
core   +1 more source

Correlation of immune function: gut microbiota and radiation enteritis in patients with cervical cancer [PDF]

open access: yes, 2023
Objective To investigate the relationship of immune function and gut microbiota with radiation enteritis (RE) in patients with cervical cancer. Methods Clinical data of 80 patients with cervical cancer were retrospectively analyzed.
Jing Wenjiang, Chen Jiaqi, Luo Ruonan, Ma Wu
core   +1 more source

Is the Change of Cytokines Related to Renal Damage in Children with IgA Vasculitis? [PDF]

open access: yes, 2022
BackgroundThe long-term prognosis of IgA vasculitis (IgAV) depends on thedegreeof renal damage. Studies on the pathogenesis of renal injury in IgAV have found that cytokines play an important role in mediating and driving the process of renal damage ...
WANG Mengdi, DU Yue
core   +1 more source

Clinical Management and Genetic Features of 3 Cases of Shwachman-Diamond Syndrome [PDF]

open access: yes, 2022
BackgroundShwachman-Diamond syndrome (SDS) is a rare autosomal recessive genetic disease that has complex and various clinical presentations. With the increase in application and clinical sensitivity of genome sequencing, the diagnoses of SDS in children
SUN Qing, XIE Yao, WU Penghui, LI Shuo, ZHAO Weihong
core   +1 more source

外周血T淋巴细胞亚群及血小板活化指标在弥漫性大B细胞淋巴瘤患者中的诊断价值

open access: yesZhongguo shiyan zhenduanxue, 2020
目的探讨外周血T淋巴细胞亚群及血小板活化指标在弥漫性大B细胞淋巴瘤患者中的诊断价值。方法选取2015年1月—2016年5月我院收治的49例弥漫性大B细胞淋巴瘤患者为观察组,同期49名同龄健康体检者为对照组,检测并比较两组的外周血T淋巴细胞亚群及血小板活化指标水平,并分析不同分期弥漫性大B细胞淋巴瘤患者上述检测结果的差异;采用Logistic回归分析上述外周血T淋巴细胞亚群及血小板活化指标与弥漫性大B细胞淋巴瘤的关系。结果观察组外周血T淋巴细胞亚群指标CD3+、CD4+及NK水平均低于对照组,CD8 ...
徐玉秀, 姜芳, 马东升, 王萌
doaj  

Arsenic Trioxide Induces T cell Apoptosis and Prolongs Islet Allograft Survival in Mice [PDF]

open access: yes, 2015
目的:作为一种最有潜力的I型糖尿病的治疗方法,胰岛移植目前已经应用于临床。然而,免疫因素特别是T细胞介导的移植物活性损伤与功能丧失是胰岛移植应用的一大障碍。一直以来,科学家们都在寻找适用于胰岛移植的新型免疫抑制剂。三氧化二砷是临床上治疗早幼粒细胞白血病的特效药,最近被证明能够抑制同种异体心脏移植排斥反应。在此基础上,本文研究了三氧化二砷对同种异体胰岛移植免疫排斥的抑制作用,以及三氧化二砷与雷帕霉素联合诱导免疫耐受的可能作用机制。 方法:我们首先检测了三氧化二砷对胰岛细胞的毒性作用 ...
高畅
core   +1 more source

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