Results 1 to 10 of about 6,538 (165)
Zhongshan Daxue xuebao. Yixue kexue ban, 1980 人体的免疫监视机构包括细胞免疫、体液免疫和补体系统。对肿瘤的免疫反应,以细胞免疫为主。但近几年对体液免疫(包括补体)也日益重视,研究细胞免疫与体液免疫的相互关系,对于进一步深入了解肿瘤发生发展的免疫机制有着重要的意义。 由抗体介导的细胞溶解需要补体的参与,这提示血清总补体的改变与肿瘤的发病有一定关系。近年有不少关于肿瘤病人血清补体研究的报道,但有些结果互相矛盾.
简志瀚
doaj +2 more sources
SARS‐CoV‐2 infection as cause of in‐utero fetal death: regional multicenter cohort study
Ultrasound in Obstetrics &Gynecology, Volume 62, Issue 6, Page 867-874, December 2023., 2023 ABSTRACT Objective Placental infection with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) can lead to placental insufficiency and in‐utero fetal death (IUFD). The objective of this study was to confirm and quantify the extent to which fetoplacental infection with SARS‐CoV‐2 is a cause of fetal death.
M. Nkobetchou +9 more
wiley +1 more source
Journal of Diabetes, Volume 15, Issue 12, Page 1081-1094, December 2023., 2023 Highlights Glucagon receptor (GCGR) monoclonal antibody (mAb) improves cardiac function and attenuates microvascular damage in db/db mice. GCGR mAb ameliorates the oxidative stress of cardiac microvascular endothelial cells in diabetic mice. GCGR mAb counteracts the diabetes‐induced upregulation of carnitine palmitoyltransferase 1B, optic atrophy type ...
Peng Wang +6 more
wiley +1 more source
Journal of Diabetes, Volume 15, Issue 11, Page 931-943, November 2023., 2023 Highlights Similar antibody response to COVID‐19 inactivated vaccine between healthy controls (HCs) and patients with type 2 diabetes mellitus (T2DM) after a booster shot vaccine within 6 months. Patients with T2DM have reduced antibody response after receiving the third dose of the COVID‐19 vaccine for more than 6 months. Both HCs and T2DM showed poor
Haolong Li +6 more
wiley +1 more source
Successful surgical removal of a pheochromocytoma in a mare via trans‐costal approach
Equine Veterinary Journal, Volume 55, Issue 6, Page 1012-1020, November 2023., 2023 Abstract Background Pheochromocytomas have been previously reported in horses, but successful antemortem diagnosis and surgical removal without recurrence of clinical signs have not been described. Objective To report the clinical presentation, diagnostic evaluation, surgical technique, anaesthetic management and post‐operative care of a mare diagnosed
Thomas J. O'Brien +6 more
wiley +1 more source
Veterinary Dermatology, Volume 34, Issue 5, Page 425-440, October 2023., 2023 Background – While the clinical features were described recently, the histopathological characterisation of trunk‐dominant canine pemphigus foliaceus (PF) is lacking, and whether it differs from classic facial or insecticide‐triggered PF is unknown. Hypothesis/Objectives – This study describes the histopathological findings of trunk‐dominant PF, and ...
Natalie Katharina Yvonne Gedon +6 more
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2023 自然杀伤（NK）细胞是T细胞后具有临床应用前景的另一类抗肿瘤免疫细胞。NK 细胞的活性主要受其表面受体和免疫微环境的调控，胶质瘤较强的免疫抑制性肿瘤微环境使NK细胞免疫治疗效率较低。本综述从胶质瘤-NK细胞交互作用角度讨论NK细胞在脑胶质瘤免疫治疗中作用的最新研究进展，总结靶向NK 细胞的化合物、单克隆抗体和细胞因子疗法，重点讨论了基因修饰的NK细胞在胶质瘤免疫治疗的现状及趋势，以及胶质瘤细胞的相关免疫逃逸分子机制，为基于NK细胞的免疫治疗神经胶质瘤提供理论依据和新的思路。
孙士隆, 陈保东
doaj
, 2007 通过对培养时间、培养温度、刀豆蛋白A(ConA)质量浓度和鳗鲡血清质量分数4个参数的测定,确定欧洲鳗鲡(Anguilla anguilla)外周血淋巴细胞转化试验四甲基偶氮唑(MTT)法的实验条件。结果表明,在培养时间为42-90 h,培养温度分别为15.0℃、20.0℃、25.0℃和30.0℃时,细胞培养液中ConA质量浓度分别为0、10μg/mL、20μg/mL和30μg/mL,鳗鲡血清质量分数分别为0、5%、10%和15%时,淋巴细胞于20.0℃、含10μg/mL ConA,
关瑞章, 冯建军, 郭松林
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Biodegradable Mg Alloys: Enhancing Anti‐tumor Immunity in Cancer Therapy
Rare Metals, Volume 45, Issue 4, April 2026.ABSTRACT Magnesium (Mg) alloys, as biodegradable metallic materials with excellent biocompatibility and mechanical properties, demonstrate significant advantages. In the field of immunotherapy, they present a promising potential option for enhancing therapeutic outcomes and hold broad prospects for application.
Can Feng +8 more
wiley +1 more source
Construction of CpG-Au@HBc virus like particles and study of their membrane translocation mechanism, immunostimulary effect [PDF]
, 2016 乙肝病毒核心蛋白病毒样颗粒（HepatitisvirusBviruscoreproteinviruslikeparticles，HBcVLPs）因其不具有乙肝病毒的复制能力而又具备较强的免疫原性而被广泛应用于构建新型疫苗。另一方面，HBcVLPs的正二十面体空腔结构和解聚/自组装特性使得其还能够作为纳米载体呈递基因、纳米粒子等。本课题利用HBcVLPsC末端的富集正电荷序列可以通过静电吸引力与核酸相互作用的特点，构建了一种同时包裹有CpG寡核苷酸链（CpGODNs）佐剂和金纳米粒子的HBcVLPs ...
王雅润
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