Relationship Between Peripheral Blood T Lymphocyte Subsets and Prognosis of Patients with Advanced Non-small Cell Lung Cancer Treated with Camrelizumab [PDF]
Objective To explore the relationship between peripheral blood T lymphocyte subsets and prognosis of patients with advanced non-small cell lung cancer (NSCLC) who received treatment with camrelizumab.
DONG Changhong +4 more
core +1 more source
Efficacy and safety of hypertonic dextrose prolotherapy for patients with post-herpetic neuralgia [PDF]
Objective·To investigate the efficacy and safety of hypertonic dextrose prolotherapy (DPT) in the treatment of postherpetic neuralgia.Methods·Seventy-eight patients with postherpetic neuralgia who visited the Department of Pain of The Affiliated Hospital
CHEN Liping +5 more
core +1 more source
Immunomodulatory Effect of Short-Term Administration of Cordyceps militaris on Mice in Different States [PDF]
In order to investigate the immunomodulatory effects of short-term administration of Cordyceps militaris on mice in different states and explore its application value as an immunomodulator, Kunming (KM) mice were randomly divided into a low-dose group ...
ZHANG Meina, ZHAO Nannan, LIAO Siqing, WANG Shenghou, WANG Ze
core +1 more source
Construction of predictive model for programmed death-1 inhibitor-related endocrine adverse events [PDF]
ObjectiveTo identify the independent predictors of programmed death-1 (PD-1) inhibitor-related endocrine adverse events and construct a clinically usable risk prediction model. MethodsA total of 302 patients with solid tumors treated with PD-1 inhibitors
Jiaying SHI +7 more
core +1 more source
T lymphocyte subsets and Kv1.3 channel in the atherosclerotic plaque of rats [PDF]
, 2010 目的：研究大鼠动脉粥样硬化斑块中CD4+及CD8+淋巴细胞亚群的表达，探究Kv1.3通道蛋白与活化的T淋巴细胞间的关系。 方法：采用高脂饲料喂养联合维生素D3负荷的方法建立大鼠动脉粥样硬化模型（12周），喂养过程中称重，在喂养12周后空腹24小时抽血并处死，检测血脂，并留取主动脉行HE染色及免疫组织化学检测。采用IPP图像处理软件计算平均光密度。 结果：血脂示动脉硬化组TC、LDL-C与对照组比较明显升高（P0.05），动脉硬化组TG较对照组低（P>0.05）；动脉硬化组主动脉管壁内膜明显增厚 ...
刘磊
core
Immunological and Neuroendocrine Changes of Depression and Effect Of Psychotherapy [PDF]
, 2003 抑郁症是一种常见的精神病理状态或综合征.它有着较高的发病率并且发病年龄日趋年轻化,给人们的工作和生活造成了不同程度的影响 ...
林文娟, 迟松
core +1 more source
Zhongguo shiyan zhenduanxue, 2004 目的 检测血清固定梅毒患者外周血T淋巴细胞亚群及NK淋巴细胞 ,探讨梅毒患者血清固定与细胞免疫的相关性。方法 应用流式细胞仪检测 2 2例血清固定梅毒患者外周血T淋巴细胞亚群及NK淋巴细胞 ,并与 30例健康人群的检测结果相对照。结果 血清固定梅毒患者外周血CD3及CD4淋巴细胞均低于对照组 ,差异有显著性 （P
杨日东 +6 more
doaj
Zhongguo shiyan zhenduanxue, 2003 目的 研究SARS患者T淋巴细胞亚群水平。方法 用流式细胞术对 7例SARS患者的外周血T淋巴细胞亚群进行系列检测 ,并选择 2 7名HIV感染者、5名急性腮腺炎和 7名麻疹患者作疾病对照 ,另选 2 0名健康者作正常对照。结果 SARS患者CD3、CD4和CD8绝对数显著低于疾病对照和正常对照 ;但CD4百分率偏高、CD8百分率偏低 ,CD4 CD8比值显著高于疾病对照组。疾病日期与T淋巴细胞亚群结果密切正相关。另外 ,SARS患者CD3+ CD4 + CD8+ 淋巴细胞百分率明显增高。结论 ...
沈芳 +6 more
doaj
The analysis of peripheral blood lymphocyte subsets and cerebrospinal fluid of neurosyphilis patients [PDF]
, 2014 梅毒是由梅毒螺旋体（Treponemapallidum，Tp）引起的严重危害人类健康的性传播性疾病。Tp可以在疾病的任何阶段入侵中枢神经系统，引起神经梅毒。由于神经梅毒临床症状复杂，误诊与漏诊率极高，早期诊断非常重要。目前，神经梅毒的诊断主要是依靠患者的病史、临床症状与体征、血液和脑脊液（CSF）的相关实验室检查。本课题分析了52例HIV阴性的神经梅毒患者外周血淋巴细胞亚群及CSF常规、生化、免疫实验室指标的变化，通过兔感染模型，分析经Tp感染后，新西兰兔血清RPR、TPPA ...
刘桂丽
core
Slective Kv1.3 blocker inhibit the over actived CD4+ T cells in atherosclerosis rats [PDF]
, 2011 目的：研究CD4+T淋巴细胞上Kv1.3通道在大鼠AS疾病过程中的作用，探讨特异性阻断Kv1.3通道对大鼠AS病情的影响以及可能的机制。 方法：实验动物分为对照组、模型组和药物处理组。模型组给予初始维生素D3负荷量腹腔注射，联合高脂饲料持续喂养（8周）；药物处理组在模型组的基础上加用特异性Kv1.3通道阻断剂ShK(L5)，10ug/kg/d，皮下注射，持续8周。分离大鼠脾脏淋巴细胞，流式细胞术检测脾脏淋巴细胞中CD4+T细胞在总T淋巴细胞中所占的比例。利用免疫磁珠法分选出脾脏中的CD4+T细胞 ...
付莉
core